Chromatography

Latest Chromatography Articles

Articles Chromatography Product Highlights

As Easy as 1, 2, 3: Achieving Purification Success with a New Two-Mode Chromatography Resin

May 13, 2025

1.5k

A common misconception is that stronger is always better. However, Nuvia wPrime 2A Media, a weak anion exchange hydrophobic interaction (AEX-HIC) mixed-mode chromatography resin, has won over purification scientists. Read about diverse use cases for Nuvia wPrime 2A Media and see the data for yourself.

Chromatography General Interest Videos

Bio-Rad’s Downstream Process Development Support and Services

May 13, 2025

714

Bio-Rad’s Chromatography Support Scientist, Artur Stanczak, discusses the company’s comprehensive downstream process development services. From method development to troubleshooting, Bio-Rad provides specialized support to help customers overcome bioprocessing challenges. Access tools, case studies, and expert guidance to optimize processes and advance biomanufacturing efforts in this informative video.

More Chromatography Articles

Development of an IEX Purification Process for Lentiviral Vectors

278 February 11, 2025

Evaluation of a New Multimodal Anion Exchange Resin for Emerging Biotherapeutic Process Challenges

305 February 11, 2025

6 Essential Considerations for Choosing Your Chromatography Resin

955 November 12, 2024

Coming Together Is the Beginning: Working Together Is the Success

235 November 12, 2024

Developing Efficient Downstream Purification Processes for Bispecific Antibodies

328 November 12, 2024

Enhancing Biotherapeutic Purification Workflows with Mixed-Mode Chromatography

820 August 13, 2024

Strategies to Address Large Molecule Purification Challenges

209 August 13, 2024

CHT Chromatography Media: 5 Essential Facts

461 June 11, 2024

Nature’s Lipid Nanoparticles: Challenges and Opportunities in Isolation and Analysis of Extracellular Vesicles

2.1k June 11, 2024

Scalable AAV Vector Purification Workflow Using AEX and Mixed-Mode Chromatography

726 February 12, 2024

Automated Multicolumn Monoclonal Antibody Purification

499 November 14, 2023

mAb Purification Process Development Using Mixed-Mode Resins — The DOE Approach

511 November 14, 2023

Unraveling the Mysteries of Molecular Machines

566 August 8, 2023

Efficient and Rapid Purification of E. coli–Expressed Toxin Recombinant Protein Fragments

359 August 7, 2023

Next-Generation Chromatography Teaching Labs Set Students Up for Success

572 May 10, 2023

Assessing Viral Clearance in Early-Phase Process Development

302 May 10, 2023

Scalable Purification Strategies for Viral Vectors and Vaccines

443 February 14, 2023

Solving Protein Purification Challenges

1.4k October 11, 2022

What You Need to Know About Packing Resins at Process Scale

487 October 11, 2022

Single-Step Influenza Virus Purification Using an Anion Exchange Resin

2.8k July 12, 2022

A Mixed-Mode Approach — An Alternative to a Three-Step mAb Purification Process

791 July 12, 2022

Powering Antibody Production and Purification with the NGC Chromatography System

662 April 12, 2022

Manufacturing a Recombinant Retrovirus — Downstream Purification Process Development

260 April 12, 2022

The Process of Resin Screening

1.7k January 11, 2022

A Scalable Immobilized Metal Affinity Chromatography Media for Process Purification

663 January 11, 2022

Bioprocessing Recombinant Proteins

1k September 14, 2021

Two-Step Purification of Low-Expressing Recombinant Exoprotein A Using Mixed-Mode Chromatography

425 September 14, 2021

Single-Step Column Purification for H1N1 Virus
Using Nuvia HP-Q AEX Resin

543 June 8, 2021

Purification of Untagged Proteins Made Attainable for Any Researcher

1.3k March 8, 2021

Automate Your Antibody Purification Workflow at Preparative and Analytical Scale

490 January 20, 2021

Are biofuels good for the planet?

428 December 8, 2020

Serving your Downstream Purification Needs

506 December 8, 2020

How to Make a Successful Vaccine

423 September 9, 2020

Analyzing Carbohydrates

2.8k June 10, 2020

Biosimilar Purification with Ion Exchange and Mixed-Mode Resins

551 February 12, 2020

Hanging with My Chromies Podcast Series

6.3k December 11, 2019

Maximizing the Efficiency of Production Workflows with NGC Chromatography Systems

691 December 11, 2019

Integrating Viral Clearance into Your Process Development — A Case Study Using a Mixed‑Mode Chromatography Resin

514 November 13, 2019

Challenging the Microbial Sanitization of a Liquid Chromatography System

2.5k November 13, 2019

Purification of Antibodies with Nuvia aPrime 4A Hydrophobic Anion Exchange Resin

2.2k August 13, 2019

A New AEX Mixed-Mode Chromatography Resin for High Selectivity and Recovery

758 June 11, 2019

Discover Our Capabilities

677 April 10, 2019

Stop Compromising between High Yield and High Purity in Downstream Purifications

1.2k March 12, 2019

Changing the Treatment Landscape with the Development of Biologics

1.4k February 13, 2019

A Model System for Fast Screening of Optimal Protein Purification Conditions

2k January 9, 2019

Single-Step Influenza and Dengue Virus Purification with Mixed-Mode CHT Ceramic Hydroxyapatite XT Media

1.6k October 9, 2018

Large Biomolecule Purification with a New High-Performance Anion Exchange Resin

578 October 9, 2018

A New Mixed-Mode Media for Downstream Purification

447 October 9, 2018

Got Purification Troubles?

976 August 15, 2018

A Resin Built Specifically for Large Biomolecule Purifications

1.7k July 10, 2018

Increase Yield and Reproducibility While Saving Time by Automating Recombinant Protein Purification

321 July 10, 2018

Improve Your Protein Purification Process Economy with CHT Ceramic Hydroxyapatite XT Media

1.6k June 12, 2018

Introducing the NGC™ Fraction Collector for Discovery to Process-Scale Protein Purification

760 February 13, 2018

Minimizing On-Column Monoclonal Antibody Aggregate Formation

3.6k January 9, 2018

Practical Experimental Design for Mixed-Mode Resins

756 October 11, 2017

An IMAC Resin for a Highly Productive Histidine-Tagged Protein Purification Process

1.1k August 9, 2017

Modern Improvements to Classic Technologies: Innovating Electrophoresis and Chromatography Upstream of Protein Characterization to Speed Up Research

1.1k June 15, 2017

From Optimization to Automation: Multidimensional (Multi-D) Histidine-Tag Protein Purification

1.3k October 13, 2016

Coupling Automated Chromatography with Faster Confirmation of Purity and Yield

535 October 13, 2016

Attaching a Dynaloop to the NGC™ Chromatography System

632 August 11, 2016

Calibrating the pH Valve on the NGC™ Chromatography System

416 August 11, 2016

Tips and Strategies for Successful Purification of Your Proteins

1.1k August 11, 2016

Synthesis and Purification of Recombinant Proteins — A Success Story

1.2k July 15, 2016

Removing Air Bubbles from the NGC™ Chromatography System

767 July 15, 2016

Using the Air Sensor on the NGC™ Chromatography System

529 July 15, 2016

Purifying Difficult-to-Purify Proteins

4k June 16, 2016

How Do You Automate a Multicolumn Protein Purification?

501 May 11, 2016

Mixed-Mode Chromatography for mAb S Aggregate Removal: Comparison of CHT™ Ceramic Hydroxyapatite, Capto adhere, and Capto adhere ImpRes

1.7k March 8, 2016

How Does the Mixed Mode Interaction of a Media Help Achieve High Selectivity and Resolution?

445 February 9, 2016

Chromatography: Everything You Need to Know about Your Peaks

26.1k January 12, 2016

High-Processivity Sso7d Fusion Polymerase Improves qPCR Results

743 December 8, 2015

Four Tips for Developing a Sample Prep Protocol for SDS-PAGE or Chromatography

615 September 4, 2015

Five Tips for Picking the Right Cell Disruption Method for Protein Analysis

1k September 4, 2015

Bio-Rad’s Multi-D Method Addresses Unmet Chromatography Needs

740 September 2, 2015

Automated Multi-D Chromatography on the NGC™ System

495 July 14, 2015

Advantages of Multidimensional (Multi-D) Chromatography Using the NGC™ Chromatography System over Traditional Sequential Chromatography

1.8k July 14, 2015

Tips for Keeping Your NGC™ Chromatography System in Great Shape

331 February 10, 2015

Tips for Using Chromatography Columns with Your NGC™ Chromatography System

353 February 10, 2015

Tips for Sample Preparation with Your NGC™ Chromatography System

253 February 10, 2015

Tips for Storing Proteins Purified on Your NGC™ Chromatography System

244 February 10, 2015

Tips for Preparing and Using Buffers with Your NGC™ Chromatography System

394 February 10, 2015

NGC System Tour and Configurator

457 October 8, 2014

Modeling Natural Killer Cell Receptors with the NGC Chromatography System

272 October 6, 2014

Purification Trends: How Smart is Chromatography Automation?

762 July 8, 2014

Protein Purification Workflow Development Using Bio-Rad’s NGC™ Chromatography System

3.5k May 13, 2014

Unlocking the Structures of Natural Killer Cell Receptors with the NGC™ Chromatography System

719 April 8, 2014

The Chromatography Chronicles Part 5: Chromatography You Can Count On

430 November 12, 2013

Stand Up Against Downtime

211 November 11, 2013

Learning Curve Blues

196 October 8, 2013

The Chromatography Chronicles Part 4: Chromatography’s Intuitive Side

608 October 2, 2013

Bench Buzz – Protein Purification Product Testers

206 September 10, 2013

The Chromatography Chronicles Part 3: Adding, Swapping, and Scaling — Better Chromatography through Modular Design

470 September 10, 2013

Buying a New Preparative Protein Purification System – You Have a New Choice

360 August 13, 2013

The Chromatography Chronicles Part 2: The Chromatographers Who Came in from the Cold

628 August 13, 2013

Vote Yes for Better Chromatography — The Results Are In!

195 July 9, 2013

The Chromatography Chronicles Part 1: The Votes Are in — Customer Voices and the NGC Chromatography System Design Process

484 July 9, 2013

Investigating Protein Translation with the NGC™ Chromatography System

337 February 14, 2013

Investigating Protein Translation with Bio-Rad’s NGC Chromatography System

846 February 7, 2013

Stellan Hjertén Wins the California Separations Science Society Award

480 October 21, 2011

C-96 Autosampler for Reliable Protein Purification Sample Application

441 June 15, 2011