Large-scale downstream processing of viruses can face a range of obstacles different from those of many biotherapeutics. These challenges mostly arise from the size and complexity of the virus, which can affect product purity and recovery. Improvements for purification tools are necessary to overcome these challenges and must be engineered for easy scalability to meet manufacturing demands. In this video, Dr. Mark Snyder discusses common difficulties when developing purification strategies for vaccine production and gene therapy. He also explores innovative resin designs and functionalities and examines both recent case studies and current processes that benefit from these resins and purification strategies.

Topics covered include:

  • Designing tools to address challenges
  • Demonstration of benefits from novel designs
  • Discussion of current purification platforms

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