ArticlesDroplet Digital PCR (ddPCR)Drug Discovery and DevelopmentFeatured StoriesGeneral Interest

A New International Standard to Measure DNA?

From quantifying a patient’s tumor DNA to counting the viral load of an individual infected with COVID-19, the breadth of digital PCR (dPCR) applications continues to grow and fulfill critical scientific needs. dPCR offers the ability to count nucleic acid molecules directly, rather than extrapolating the quantity from standard curves as with many other methods. By harmonizing diagnostic procedures on dPCR platforms, the scientific and medical communities can become more coordinated and efficient.
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ArticlesDrug Discovery and DevelopmentGeneral Interest

Data Standardization

Increasingly, biopharma research & development experimental data are siloed and stored in varying formats. This makes it difficult to search, retrieve and share data. Furthermore, these data are often not interoperable, making it impossible to compare. Data needs to be better managed to be more collaborative, shareable, and interoperable, in order to accelerate research and continue making breakthroughs. Data standardization aims to forge a path toward machine-readable and actionable data that can be found, accessed, and reused with minimal human intervention.
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ArticlesCell BiologyProtocols and Tips

7 Tips for Purchasing Your Next Cell Sorter

Presented here are some tips to help you avoid buyer’s remorse and make an educated decision about which instrument to purchase. These tips provide you with the tools to make an informed decision when purchasing a cell sorter.
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ArticlesProduct HighlightsReal-time qPCR/PCR

Introducing the CFX Opus Real-Time PCR Systems —
A Modern Take on Bio-Rad Consistency

Coming soon: The next iteration in Bio-Rad’s tradition of qPCR excellence. The compact CFX Opus Real-Time PCR System is more connected, consistent, and easier to use than ever before, and is available in 96- and 384-well formats. The CFX Opus Systems launch with our new BR.io cloud platform and the latest version of CFX Maestro Software, for complete instrument control and data analysis capabilities.
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ArticlesCell BiologyResearch Highlights

Sorting an Old Problem: Are Cells Stressed by Fluorescence-Activated Cell Sorting?

Fluorescence-activated cell sorting is a valuable tool for research, but could the physical forces of sorting stress the cells, altering their behavior and confounding experimental results? Recent research found that although cell sorting activated p38 MAPK stress signaling, no functional or structural changes were observable. The results indicate that jet-in-air systems such as the Bio-Rad S3e Cell Sorter do not alter cell behavior.
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ArticlesChromatography

How to Make a Successful Vaccine

As phase 3 clinical trials of investigational vaccines for COVID-19 begin in the U.S., you may be wondering what it takes to make an effective vaccine? In case you missed it, check out our Hanging with My Chromies podcast, episodes 6 and 10 on vaccine development and viral spread, and learn about the role chromatography plays in making a successful vaccine.
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ArticlesPodcasts

BioRad.io Podcast Series

The BioRad.io podcast series is focused on R&D informatics, introducing you to people responsible for implementing systems and technologies to a diverse set of use-cases. Join us every month to see what you can learn.
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ArticlesCell BiologyFeatured StoriesProtocols and Tips

10 Tips for Setting Up a Successful Cell Sorting Experiment

Incorporating fluorescence-based cell sorting into your lab grants you powerful access to new research areas and rarer cell types without sacrificing efficiency or results. New, powerful techniques like CRISPR and single-cell analysis are enhanced by the isolation of specific cells. But isolating cell populations of the right quality and quantity is both challenging and time consuming. We offer some tips to set yourself up for success and get the most out of your sorts.
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ArticlesDrug Discovery and DevelopmentGeneral Interest

Globally Aware Genomes — an Informatics Challenge

The Human Genome Project was completed nearly two decades ago, in 2003. The primary vision of this project was to produce a human reference genome, a representative example of the set of genes in one idealized individual human. However, the currently available reference genomes do not represent the genetic diversity found across different human populations. As such, any downstream products (drugs therapies, personalized medicine, etc.) derived from the human genome will not accurately represent the vast majority of the human population.
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Droplet Digital PCR (ddPCR)Past WebinarsWebinars

Expert Coffee Chats: Coffee Chat #4 – Droplet Digital PCR in Cell and Gene Therapy

Presented by: Matthew L. Turner, PhD, Field Application Scientist – ddPCR, NGC and qPCR, Tara Ellison, PhD, Senior Field Application Scientist

Date: June 17, 2020
Time: 9 AM, U.S. Pacific time

  • Robust methodology for viral titer using ddPCR
  • Precise copy number determination & improved confidence in acceptance criteria
  • Enhance your throughput and minimize hands-on time
  • Learn how ddPCR is used in other key applications
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