ArticlesDroplet Digital PCR (ddPCR)General Interest

Bispecific Antibodies and Cancer Immunotherapy

Bispecific antibodies (bsAbs) are an important addition to the immuno-oncology toolbox. Designed to recognize two distinct epitopes, bsAbs have enhanced binding, specificity, and efficacy compared to current monovalent antibody therapeutics, making them exciting candidates for more targeted cancer treatments. Learn about bsAbs and how our tools can help scientists with their research on therapeutic candidates.
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ArticlesDroplet Digital PCR (ddPCR)Drug Discovery and Development

Monitoring CAR T-Cell Therapy Quality with Droplet Digital PCR

The CAR T-cell manufacturing process involves high potential for variability. Learn how sensitive ddPCR assays can be used to ensure safety and efficacy.
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ArticlesDroplet Digital PCR (ddPCR)Drug Discovery and Development

CDMOs Drive Cell and Gene Therapy from Behind the Scenes

As more of the cell and gene therapies revolutionizing healthcare are approved for use, innovator companies usually get the credit. But many therapies would never make it to market without the expertise and capabilities of contract development and manufacturing organizations (CDMOs) operating behind the scenes. Learn more about how CDMOs enable new cell and gene therapies to come to market, and how Droplet Digital PCR can help.
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ArticlesCOVID-19Droplet Digital PCR (ddPCR)

Top 5 Takeaways from ddPCR World 2021

Precision diagnostics for cancer. COVID-19 surveillance in wastewater. Quality control of cell and gene therapies. These were just a few of the cutting-edge applications on display at the Droplet Digital PCR (ddPCR) World 2021 symposium. Recapping the event in 5 takeaways, moderator Francisco Bizouarn shares how international experts are leveraging ddPCR technology to solve today’s scientific and public health problems.
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ArticlesDroplet Digital PCR (ddPCR)General InterestResearch Highlights

Advancing Molecular Diagnostics for Myelodysplastic Syndrome

No patient who has survived cancer wants to hear that they’ve relapsed. But hearing it sooner rather than later can dramatically increase the chances of finding a successful, potentially life-saving treatment. Using next-generation sequencing and Droplet Digital PCR, researchers at the University of Uppsala aim to detect relapse by monitoring patient-specific biomarkers. Read about their ongoing clinical study.
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Success and QC in Cell and Gene Therapy
ArticlesDroplet Digital PCR (ddPCR)Drug Discovery and Development

With Cell and Gene Therapies, Success and Quality Control Go Hand-in-Hand

While the FDA has approved Abecma, the first CAR-T cell therapy in its class, regulatory approval is just the beginning for cell and gene therapies. Such therapies’ safety and financial viability rest on a robust manufacturing and quality control program with the flexibility to scale up and out. Droplet Digital PCR is a sensitive biopharmaceutical quality control tool, offering absolute quantification of nucleic acids and other molecules in a sample.
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ArticlesDroplet Digital PCR (ddPCR)Drug Discovery and Development

The Role of ddPCR in Developing Safe and Effective AAV-Based Gene Therapies

Developing adeno-associated virus (AAV)-mediated gene therapies requires accurate and precise quality control. Read how Droplet Digital PCR technology provides the sensitivity needed to assess the potential safety and effectiveness of these treatments.
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ArticlesCOVID-19Droplet Digital PCR (ddPCR)Featured StoriesGeneral Interest

Top Questions from Our Wastewater Surveillance Webinar

The COVID-19 pandemic has captured the attention of the world and won’t let go. And that has sparked efforts for creative solutions in some surprising places. Wastewater is not where most peoples’ minds go first when they think of airborne diseases, but it holds much promise for tracing and predicting SARS-CoV-2 outbreaks.
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ArticlesDroplet Digital PCR (ddPCR)Drug Discovery and Development

Top 5 Challenges Faced by AAV Developers Today

Adeno-associated viruses (AAVs) are some of the most commonly used viral vectors for gene therapy, supporting approximately 250 clinical trials to date. However, the manufacturing processes are challenging to scale. Read about five key issues that gene therapy manufacturers who use AAVs need to look out for.
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ArticlesDroplet Digital PCR (ddPCR)Drug Discovery and DevelopmentFeatured StoriesGeneral Interest

A New International Standard to Measure DNA?

From quantifying a patient’s tumor DNA to counting the viral load of an individual infected with COVID-19, the breadth of digital PCR (dPCR) applications continues to grow and fulfill critical scientific needs. dPCR offers the ability to count nucleic acid molecules directly, rather than extrapolating the quantity from standard curves as with many other methods. By harmonizing diagnostic procedures on dPCR platforms, the scientific and medical communities can become more coordinated and efficient.
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