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Integrating Viral Clearance into Your Process Development — A Case Study Using a Mixed‑Mode Chromatography Resin

Presented by: Akunna Iheanacho, Director of Research and Development at Texcell – North America
Xuemei He, R&D Manager, Chromatograpy Media Chemistry at Bio-Rad Laboratories

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Learn about evaluating viral clearance using a DOE approach with a mixed-mode chromatography resin.

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Challenging the Microbial Sanitization of a Liquid Chromatography System

When developing biologics or biotherapeutics, it is imperative that no contaminating or hazardous residual components from the organisms responsible for protein expression remain after purification. See how the NGC Chromatography System was challenged with microbes and efficiently sanitized, making it ideal for the small-scale production of biotherapeutics.
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Hanging with My Chromies Podcast Series

The Hanging with My Chromies podcast series is focused on the many surprising applications of chromatography and the stories surrounding them. Join us every month to see what you can learn.
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Purification of Antibodies with Nuvia aPrime 4A Hydrophobic Anion Exchange Resin

Our new hydrophobic anion exchange mixed-mode resin, Nuvia aPrime 4A, has been developed to overcome existing challenges in antibody purification. See how we purified an acidic and basic antibody through bind-elute and flow-through modes of purification, respectively, and helped to improve process productivity and economy.
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A New AEX Mixed-Mode Chromatography Resin for High Selectivity and Recovery

Presented by: Xuemei He, PhD, R&D Manager, Chromatography Media Chemistry, Bio-Rad Laboratories

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This webinar highlights the properties of Bio-Rad’s newest hydrophobic AEX chromatography resin, Nuvia aPrime 4A, which is designed to facilitate selective and reversible binding of target molecules for higher purity and recovery over traditional chromatography resins.

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Discover Our Capabilities

From flow cytometry to chromatography to western blot imaging to PCR plastics, learn more about Bio-Rad and see what’s possible in your research.
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Stop Compromising between High Yield and High Purity in Downstream Purifications
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Stop Compromising between High Yield and High Purity in Downstream Purifications

When it comes to downstream protein purifications, does it feel like you’re in a constant tug of war between high yield and high purity? With Bio-Rad’s Nuvia aPrime 4A Resin, you don’t have to choose. With both ion exchange and mixed-mode properties, see how the resin is able to deliver simultaneous purity and yield, for even difficult-to-purify proteins.
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Changing the Treatment Landscape with the Development of Biologics
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Changing the Treatment Landscape with the Development of Biologics

Biologics are transforming the healthcare landscape and bringing us closer to the realization of personalized solutions to our health problems. Learn about what biologics are and how protein purification plays a key role in their overall success as a therapeutic.
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A Model System for Fast Screening of Optimal Protein Purification Conditions
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A Model System for Fast Screening of Optimal Protein Purification Conditions

See how you can efficiently reduce identification of optimal protein purification conditions from five days to just 18 hours. All you need is a DOE model and the Multivariable Scouting tool and automation abilities of the NGC Chromatography System.
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Single-Step Influenza and Dengue Virus Purification with Mixed-Mode CHT Ceramic Hydroxyapatite XT Media

See how you can use CHT XT Mixed-Mode Media to recover over 75% of your virus in a single purification step. All this while reducing contaminating proteins by over 90% and removing over 60% of dsDNA. Get simple, fast, and reproducible viral purification with CHT XT.
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