ArticlesDrug Discovery and DevelopmentGeneral Interest

Advanced Cancer Therapeutics: Increasing Efficacy and Specificity and Reducing Toxicity

Research into human diseases has led to the development of novel monoclonal antibody drugs. These monoclonal antibody therapies have been successful because of their specificity and selectivity. However, ongoing development and successfully launching a new mAb drug require robust and reliable methods to screen for drug targets, demonstrate drug safety and efficacy, and scale up manufacturing to meet the stringent regulatory guidelines required for approval.
READ MORE →
ArticlesChromatography VideoTips and Techniques VideoVideos

Single-Step Column Purification for H1N1 Virus
Using Nuvia HP-Q AEX Resin

Learn how a team developed a single-step workflow for column purification of the Influenza A H1N1 subtype using the recently developed Nuvia HP-Q Anion Exchange Resin. This protocol is scalable, efficient, and produced good yields with high purity.
READ MORE →
ArticlesChromatographyTechnical Reports

Purification of Untagged Proteins Made Attainable for Any Researcher

High purity protein is a common requirement for biochemical and structural studies. A common approach is to recombinantly express an affinity-tagged version of the protein of interest. However, this is not always a viable option. Here we showcase how the NGC Chromatography System and prepacked chromatography columns can be utilized to develop purification workflows for untagged proteins.
READ MORE →
ChromatographyPast WebinarsWebinars

Automate Your Antibody Purification Workflow at Preparative and Analytical Scale

Presented by: Katie Schaefer, PhD, Global Product Manager, Bio-Rad
Peter Winship, PhD, Technical Product Manager, Teledyne Cetac Technologies

View on demand

Purification is a multistep process toward confirmation of a target protein’s purity. In this webinar you will learn how to automate your protein purification workflow by following the creation of a hypothetical monoclonal antibody (mAb). Dr. Schaefer and Dr. Winship expertly demonstrate how the NGC Chromatography System and the AEX-500 series Autosampler work together to maximize screening capability as well as rapidly achieve therapeutic development objectives.

READ MORE →
ArticlesChromatographyGeneral Interest

Are biofuels good for the planet?

Will the trend toward using biofuels benefit the earth? Listen in as our Chromies team discusses different types of biofuels and how chromatography plays a role in developing mass produced and energy efficient biofuels.
READ MORE →
ArticlesChromatography

How to Make a Successful Vaccine

As phase 3 clinical trials of investigational vaccines for COVID-19 begin in the U.S., you may be wondering what it takes to make an effective vaccine? In case you missed it, check out our Hanging with My Chromies podcast, episodes 6 and 10 on vaccine development and viral spread, and learn about the role chromatography plays in making a successful vaccine.
READ MORE →
ArticlesChromatographyGeneral InterestProduct Highlights

Analyzing Carbohydrates

Carbohydrates are among the most important components of foods, providing energy as well as flavor, texture, and other physical properties. Identification and quantification of carbohydrates in food is commonly performed using high-performance liquid chromatography. Bio-Rad Aminex Ion Exchange Resins have become the industry standard for carbohydrate and organic acid analysis.
READ MORE →
ChromatographyPast WebinarsWebinars

Biosimilar Purification with Ion Exchange and Mixed-Mode Resins

Presented by: Randy Drevland, PhD, Senior Applications Scientist

View on demand

Dr. Drevland presents a viable alternative workflow for the development of a HUMIRA-like biosimilar using IEX and mixed-mode resins.

READ MORE →
Hanging with My Chromies Podcast Series
ArticlesChromatographyPodcasts

Hanging with My Chromies Podcast Series

The Hanging with My Chromies podcast series is focused on the many surprising applications of chromatography and the stories surrounding them. Join us every month to see what you can learn.
READ MORE →
ArticlesChromatography VideoCustomer Stories

Maximizing the Efficiency of Production Workflows with NGC Chromatography Systems

See how an antibody expression service provider, Evitria (Zurich, Switzerland) optimized and expanded their antibody production services using the NGC Chromatography Systems to meet the growing demands of their customers.
READ MORE →