Stop Compromising between High Yield and High Purity in Downstream Purifications
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Stop Compromising between High Yield and High Purity in Downstream Purifications

Payal Khandelwal — March 12, 2019
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When it comes to downstream protein purifications, does it feel like you’re in a constant tug of war between high yield and high purity? With Bio-Rad’s Nuvia aPrime 4A Resin, you don’t have to choose. With both ion exchange and mixed-mode properties, see how the resin is able to deliver simultaneous purity and yield, for even difficult-to-purify proteins.
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Hanging with My Chromies Podcast Series
ArticlesChromatographyPodcasts

Hanging with My Chromies Podcast Series

Bioradiations Staff — March 12, 2019
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The Hanging with My Chromies podcast series is focused on the many surprising applications of chromatography and the stories surrounding them. Join us every month to see what you can learn.
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Changing the Treatment Landscape with the Development of Biologics
ArticlesChromatographyFeatured Stories

Changing the Treatment Landscape with the Development of Biologics

Leala Thomas and Payal Khandelwal — February 13, 2019
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Biologics are transforming the healthcare landscape and bringing us closer to the realization of personalized solutions to our health problems. Learn about what biologics are and how protein purification plays a key role in their overall success as a therapeutic.
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A Model System for Fast Screening of Optimal Protein Purification Conditions
ArticlesChromatographyTechnical Reports

A Model System for Fast Screening of Optimal Protein Purification Conditions

Kevin Thornton, Doris Yeung, Joe Hilario, Chelsea Pratt, and Candice Cox — January 9, 2019
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See how you can efficiently reduce identification of optimal protein purification conditions from five days to just 18 hours. All you need is a DOE model and the Multivariable Scouting tool and automation abilities of the NGC Chromatography System.
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ArticlesChromatographyTechnical Reports

Single-Step Influenza and Dengue Virus Purification with Mixed-Mode CHT Ceramic Hydroxyapatite XT Media

Yae Kurosawa, Payal Khandelwal, Daniel Yoshikawa, and Mark Snyder — October 9, 2018
254 0 0
See how you can use CHT XT Mixed-Mode Media to recover over 75% of your virus in a single purification step. All this while reducing contaminating proteins by over 90% and removing over 60% of dsDNA. Get simple, fast, and reproducible viral purification with CHT XT.
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Nuvia HP-Q
ChromatographyPast WebinarsWebinars

Large Biomolecule Purification with a New High-Performance Anion Exchange Resin

Bioradiations Staff — October 9, 2018
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Presented by: Hana Kim, PhD, Global Product Manager, Process Chromatography
Jiali Liao, PhD, Principal Scientist, Process Chromatography

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Learn about Nuvia HP-Q Resin, a new rigid bead engineered with large pores and optimized surface extenders to deliver both high binding capacity and high recovery at high flow rates. It is ideal for large molecule purification, including plasma proteins, viruses, and VLPs.

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CHT XT
ChromatographyPast WebinarsWebinars

A New Mixed-Mode Media for Downstream Purification

Bioradiations Staff — October 9, 2018
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Presented by: Daniel Yoshikawa, PhD, Global Product Manager, Process Chromatography
Mark A. Snyder, PhD, R&D Applications Manager, Process Chromatography

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Watch this webinar to learn about a new mixed-mode chromatography media used to purify biomolecules at process scale. It delivers unique selectivity and robust, uniformly sized beads with excellent pressure-flow properties ideal for bioprocess applications.

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Minimize On-Column Aggregation during mAb Purification
ArticlesChromatographyProtocols and Tips

Got Purification Troubles?

Bioradiations Staff — August 15, 2018
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Use our interactive infographic to find out how your resin-of-choice fares in on-column aggregate formation during monoclonal antibody purification. And find out what you can do to minimize these on-column aggregates.
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A Resin for Purification of Large Biomolecules
ArticlesChromatographyProduct Highlights

A Resin Built Specifically for Large Biomolecule Purifications

Payal Khandelwal — July 10, 2018
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Nuvia HP-Q is a high-performance strong anion exchange resin designed for purification of large biomolecules. See how its optimized particle and pore size leads to high target recovery and high-throughput purifications.
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ChromatographyPast WebinarsWebinars

Increase Yield and Reproducibility While Saving Time by Automating Recombinant Protein Purification

Bioradiations Staff — July 10, 2018
138 0 0

Presented by: Philip Chapman, MSc, Senior Global Product Manager

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Learn how to quickly optimize conditions prior to automating a four-step purification of a histidine-tagged recombinant protein. Automating purification reduces a multi-day process into 12 hours while increasing yield and reproducibility.

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