Customer Stories | Bio-Radiations https://www.bioradiations.com A Resource for Life Science Research Fri, 14 Nov 2025 00:25:04 +0000 en-US hourly 1 https://www.bioradiations.com/wp-content/uploads/2025/10/BR-knocked-out-60x60.png Customer Stories | Bio-Radiations https://www.bioradiations.com 32 32 Each month, join Kashef Qaadri, a biologist turned bioinformatician, as he interviews guests exploring real-world research informatics challenges through use-cases, providing insights and strategies for integrating and analyzing complex data that are driving BioPharma R&D. Bio-Rad Laboratories, Inc. false Bio-Rad Laboratories, Inc. lsgmarcomapps@gmail.com Copyright © 2019 Bio-Rad Laboratories, Inc. All rights reserved. Copyright © 2019 Bio-Rad Laboratories, Inc. All rights reserved. podcast Each month, join Kashef Qaadri, a biologist turned bioinformatician, as he interviews guests exploring real-world research informatics challenges through use-cases, providing insights and strategies for integrating and analyzing complex data that are d... Customer Stories | Bio-Radiations https://www.bioradiations.com/wp-content/uploads/powerpress/bioradio_podsq_1400x1400-400.jpg https://www.bioradiations.com/customer-stories/ Real-World AAV Empty-Full Capsid Analysis with ddPCR Technology: Insights from Matica Biotechnology https://www.bioradiations.com/real-world-aav-empty-full-capsid-analysis-with-ddpcr-technology-insights-from-matica-biotechnology1125/ Tue, 11 Nov 2025 17:55:56 +0000 https://www.bioradiations.com/?p=12940 Vericheck ddPCR Empty-Full Capsid Kits for AAV Workflows Measuring the ratio of empty to full capsids serves as a critical quality attribute (CQA) for adeno-associated virus (AAV) products and directly ...

The post Real-World AAV Empty-Full Capsid Analysis with ddPCR Technology: Insights from Matica Biotechnology first appeared on Bio-Radiations.]]> Global Lung Cancer Expert Dr. Ed Schuuring on How ddPCR Technology Powers ctDNA Analysis https://www.bioradiations.com/how-ddpcr-technology-powers-ctdna-analysis-225/ Tue, 11 Feb 2025 18:43:53 +0000 https://www.bioradiations.com/?p=12703 Characterizing biomarkers in lung cancer tumors is challenging due to the high risks associated with tissue retrieval. Liquid biopsy offers a safer alternative but requires highly sensitive and precise methods to generate robust results from minimal genetic material. In this video, Dr. Schuuring of the University Medical Center Groningen discusses how Droplet Digital PCR (ddPCR) is used in his laboratories and why this technology has become critical for his research.

The post Global Lung Cancer Expert Dr. Ed Schuuring on How ddPCR Technology Powers ctDNA Analysis first appeared on Bio-Radiations.]]> NalaGenetics Moves Pharmacogenomics from the Bench to the Clinic using qPCR: An Interview with Astrid Irwanto, Co-Founder and COO https://www.bioradiations.com/moving-pharmacogenomics-from-bench-to-clinic-224/ Mon, 12 Feb 2024 18:14:12 +0000 https://www.bioradiations.com/?p=12516 Astrid Irwanto is the co-founder and COO of NalaGenetics, a company taking a novel, personalized approach to understanding genetic susceptibility to drug reactions in Southeast Asian populations. A PhD in human genetics and postdoctoral research in genetics disease, along with personal experiences, fuel Astrid’s pursuits. In this interview, we discuss NalaGenetics’ approach to pharmacogenomics and why Astrid decided to translate her academic research to a molecular diagnostics company.

The post NalaGenetics Moves Pharmacogenomics from the Bench to the Clinic using qPCR: An Interview with Astrid Irwanto, Co-Founder and COO first appeared on Bio-Radiations.]]> Unraveling the Mysteries of Molecular Machines https://www.bioradiations.com/unraveling-the-mysteries-of-molecular-machines-823/ Tue, 08 Aug 2023 19:11:03 +0000 https://www.bioradiations.com/?p=12422 Seychelle M. Vos, PhD, has a passion for science that was ignited at a young age while exploring her parents’ garden and the natural world around her. Now she studies some of the biggest questions in genome biology: how DNA structure and chromatin influence protein transcription. The molecular machines that physically couple transcription and DNA structure by changing the position of nucleosomes, interfacing with chromatin, and compressing DNA into loops, are the focus of Vos’ research.

The post Unraveling the Mysteries of Molecular Machines first appeared on Bio-Radiations.]]> Next-Generation Chromatography Teaching Labs Set Students Up for Success https://www.bioradiations.com/next-generation-chromatography-teaching-labs-523/ Wed, 10 May 2023 08:21:16 +0000 https://www.bioradiations.com/?p=12360 Dominique Ingato, PhD, is a faculty member at MiraCosta College’s Department of Biotechnology. As one of only fifteen community colleges in California to offer a bachelor’s degree, MiraCosta College’s bachelor’s program in biomanufacturing is breaking ground. As part of this program, Ingato runs a next-generation chromatography (NGC) teaching lab, where students receive practical, hands-on training using state-of-the-art instruments, such as the NGC Chromatography System.

The post Next-Generation Chromatography Teaching Labs Set Students Up for Success first appeared on Bio-Radiations.]]> Genotype Screening in Songbirds Made Easy https://www.bioradiations.com/genotype-screening-in-songbirds-made-easy-223/ Tue, 14 Feb 2023 23:01:20 +0000 https://www.bioradiations.com/?p=12299 Christien Bowman, MSc, has traversed a path from psychology to neuroscience, and is now working on attaining his PhD in biomedicine. In this interview, we discussed how Bowman uses Chelex 100 Resin as part of a fast and cost-effective method to determine the sex of zebra finch songbirds. This work ultimately helps Bowman study a behavioral paradigm that creates autism-like features in songbirds.

The post Genotype Screening in Songbirds Made Easy first appeared on Bio-Radiations.]]> Solving Protein Purification Challenges https://www.bioradiations.com/solving-protein-purification-challenges-1022/ Tue, 11 Oct 2022 19:06:34 +0000 https://www.bioradiations.com/?p=12225 Carter Mitchell, PhD, is a protein problem solver. As Chief Science Officer at Kemp Proteins, he helps academic and industry researchers develop a range of protein therapeutics, diagnostics, and molecular tools in milligram to gram quantities with bioprocess scale in mind. In this interview, we discussed how Kemp Proteins ensures delivery of high-quality processes and protein-based products to their clients, even when working with difficult proteins.

The post Solving Protein Purification Challenges first appeared on Bio-Radiations.]]> Powering Antibody Production and Purification with the NGC Chromatography System https://www.bioradiations.com/antibody-production-with-the-ngc-system-422/ Tue, 12 Apr 2022 16:22:05 +0000 https://www.bioradiations.com/?p=12068 For this article, we spoke with Vera Dreyfuss of evitria AG, an antibody expression services provider based in Switzerland, about the role that the NGC Chromatography System has played in powering the growth and success of the company.

The post Powering Antibody Production and Purification with the NGC Chromatography System first appeared on Bio-Radiations.]]> Maximizing the Efficiency of Production Workflows with NGC Chromatography Systems https://www.bioradiations.com/maximizing-the-efficiency-of-production-workflows-with-ngc-chromatography-systems/ Thu, 12 Dec 2019 00:00:51 +0000 https://www.bioradiations.com/?p=11403 See how an antibody expression service provider, Evitria (Zurich, Switzerland) optimized and expanded their antibody production services using the NGC Chromatography Systems to meet the growing demands of their customers.

The post Maximizing the Efficiency of Production Workflows with NGC Chromatography Systems first appeared on Bio-Radiations.]]> Identifying Predictive Biomarkers for Successful Immunotherapy Treatments https://www.bioradiations.com/identifying-predictive-biomarkers-for-successful-immunotherapy-treatments/ Tue, 09 Jan 2018 23:08:16 +0000 http://www.bioradiations.com/?p=9563 Find out how the S3e™ Cell Sorter can help scientists discover new biomarkers that have the potential to become new therapies for cancer and other diseases.

The post Identifying Predictive Biomarkers for Successful Immunotherapy Treatments first appeared on Bio-Radiations.]]> The ZE5™ Cell Analyzer: Designed by Users for Users https://www.bioradiations.com/the-ze5-cell-analyzer-designed-by-users-for-users/ Wed, 15 Feb 2017 23:00:07 +0000 http://www.bioradiations.com/?p=9009 Bio-Rad’s new ZE5 Cell Analyzer is a game-changing cell analyzer that was designed with direct input from scientists and flow core labs. Karen Helm runs the flow core facility at the University of Colorado Cancer Center and was one of the experts consulted. See how ZE5 is helping her flow core users do better science.

The post The ZE5™ Cell Analyzer: Designed by Users for Users first appeared on Bio-Radiations.]]> Synthesis and Purification of Recombinant Proteins — A Success Story https://www.bioradiations.com/synthesis-and-purification-of-recombinant-proteins-a-success-story/ Fri, 15 Jul 2016 21:24:43 +0000 http://www.bioradiations.com/?p=8730 Producing highly purified proteins in large quantities is a challenge and requires modification of methods and protocols to attain high efficiency. Dr Murat Kasap from Kocaeli University, Turkey, has overcome these difficulties by taking advantage of the modularity of the NGC Chromatography System and successfully synthesized and purified cardiac troponin-I protein.

The post Synthesis and Purification of Recombinant Proteins — A Success Story first appeared on Bio-Radiations.]]> Expanding Flow Core Capabilities with the S3e™ Cell Sorter https://www.bioradiations.com/expanding-flow-core-capabilities-with-the-s3e-cell-sorter/ Wed, 13 Apr 2016 01:00:38 +0000 http://www.bioradiations.com/?p=8574 Andy Riddell, Flow Cytometry Core Facility Manager at the Wellcome Trust- MRC Stem Cell Institutes, is expanding his core facility by allowing his researchers to conduct sorting on their own. In doing so, he is now free to explore and answer the challenging flow cytometry questions that require more of his expert time. Find out how the S3e Cell Sorter has allowed Andy that freedom and how easy sorting can be for researchers.

The post Expanding Flow Core Capabilities with the S3e™ Cell Sorter first appeared on Bio-Radiations.]]> Expanding Flow Core Capabilities by Shifting Routine Sorts to Self-Sort on the S3e™ Cell Sorter https://www.bioradiations.com/expanding-flow-core-capabilities-by-shifting-routine-sorts-to-self-sort-on-the-s3e-cell-sorter/ Tue, 12 Apr 2016 20:50:48 +0000 http://www.bioradiations.com/?p=8591 To run a core flow cytometry lab is no easy task. There is always a balance between running simple sorts and developing new assays for answering complicated questions that demand pushing the limits of existing assays and the limitations of the sorters. See how Andy Riddell, a flow core manager, pushes the limits of his existing assays and how Bio-Rad’s S3e™ cell sorter is allowing him to accomplish that.

The post Expanding Flow Core Capabilities by Shifting Routine Sorts to Self-Sort on the S3e™ Cell Sorter first appeared on Bio-Radiations.]]> Using PrimePCR™ Gene Expression Assays to Understand Breast Cancer Metastasis https://www.bioradiations.com/using-primepcr-gene-expression-assays-to-understand-breast-cancer-metastasis/ Tue, 08 Mar 2016 18:47:06 +0000 http://www.bioradiations.com/?p=8546 Tumor metastasis is a complex process. It requires the ability of the cancer cells to invade their surroundings and travel to distant sites and survive. Dr. Traci Lyons studies the mechanism of COX-2 functioning in the metastasis of breast cancer cells. Find out how Dr. Lyons used Bio-Rad’s PrimePCR™ Assays to confirm COX-2 knockdown at the mRNA level.

The post Using PrimePCR™ Gene Expression Assays to Understand Breast Cancer Metastasis first appeared on Bio-Radiations.]]> Using PrimePCR™ qPCR Assays to Understand Breast Cancer Metastasis https://www.bioradiations.com/using-primepcr-qpcr-assays-to-understand-breast-cancer-metastasis/ Tue, 08 Mar 2016 08:00:43 +0000 http://www.bioradiations.com/?p=8501 Traci Lyons describes how PrimePCR Assays ended her laboratory’s struggle to find a qPCR assay that could reliably detect transcription of the cyclooxygenase-2 (Cox-2) gene, which they had identified as potentially prometastatic. Using the PrimePCR Assay for Cox-2, researchers in her lab were finally able to verify cyclooxygenase-2 knockdown, which is a necessary step toward confirming its role in breast cancer metastasis.

The post Using PrimePCR™ qPCR Assays to Understand Breast Cancer Metastasis first appeared on Bio-Radiations.]]> High Quality Gene Expression from Precious Samples — A Simplified Workflow https://www.bioradiations.com/high-quality-gene-expression-from-precious-samples-a-simplified-workflow/ Thu, 11 Jun 2015 17:45:48 +0000 http://www.bioradiations.com/?p=7099 Obtaining enough starting material to complete multiple gene expression experiments can be challenging when working with precious and limited samples. Find out how Mark Kibschull of the Lunenfeld-Tanenbaum Research Institute in Toronto determines pluripotency and differentiation of limited human embryonic stem cells using Bio-Rad's SingleShot Cell Lysis Kit, PreAmp Supermix, and PrimePCR validated primer panels. This simplified workflow allows for the gene expression analysis of hundreds of genes from as little as 100 human embryonic stem cells, and without the cumbersome step of isolating and purifying RNA.

The post High Quality Gene Expression from Precious Samples
— A Simplified Workflow first appeared on Bio-Radiations.]]> Too Many Questions, Too Little Sample: Developing a Real-Time PCR Workflow for Monitoring Gene Expression in Limited Samples https://www.bioradiations.com/too-many-questions-too-little-sample-developing-a-real-time-pcr-workflow-for-monitoring-gene-expression-in-limited-samples/ Tue, 09 Jun 2015 22:42:57 +0000 http://www.bioradiations.com/?p=7042 Traditional real-time PCR workflows often limit the number of genes that can be studied, especially when sample amounts are small. A new workflow now allows Mark Kibschull of the Lunenfeld-Tanenbaum Research Institute in Toronto to track the expression of hundreds of genes using a fraction of the starting material required by traditional methods.

The post Too Many Questions, Too Little Sample: Developing a Real-Time PCR Workflow for Monitoring Gene Expression in Limited Samples first appeared on Bio-Radiations.]]> 3 Moments of Inquiry with Bio-Rad’s pGLO™ Transformation and Inquiry for AP Biology: A ThINQ! Investigation Kit https://www.bioradiations.com/3-moments-of-inquiry-with-bio-rads-pglo-transformation-and-inquiry-for-ap-biology-a-thinq-investigation-kit/ Tue, 19 May 2015 23:15:07 +0000 http://www.bioradiations.com/?p=6512 “Inquiry-based” is the new buzzphrase in science education. But what do these learning practices look like on the ground? Visit one high school in Southern California and find out about this new approach to teaching science.

The post 3 Moments of Inquiry with Bio-Rad’s pGLO™ Transformation and Inquiry for AP Biology: A ThINQ! Investigation Kit first appeared on Bio-Radiations.]]> Investigating Cancer Stem Cells with the S3™ Cell Sorter https://www.bioradiations.com/investigating-cancer-stem-cells-with-the-s3-cell-sorter/ Tue, 09 Dec 2014 23:54:02 +0000 http://www.bioradiations.com/?p=6355 The Cancer Stem Cell model proposes that a special group of dormant cells in the cancer population plays a key role in tumor development and growth, as well as regeneration following treatment. Find out how researchers Stacy Blain and Danielle Joseph are using the S3 Cell Sorter in studying potential cancer stem cells for multiple myeloma.

The post Investigating Cancer Stem Cells with the S3™ Cell Sorter first appeared on Bio-Radiations.]]> Investigating Cancer Stem Cells with the S3™ Cell Sorter https://www.bioradiations.com/investigating-cancer-stem-cells-with-the-s3-cell-sorter-video/ Tue, 09 Dec 2014 20:00:56 +0000 http://www.bioradiations.com/?p=4430 At SUNY Downstate Medical Center in Brooklyn, New York, researchers Stacy Blain and Danielle Joseph are trying to find out how the Cancer Stem Cell model might apply to multiple myeloma. See how they use Bio-Rad’s S3 Cell Sorter to isolate a small population of cells that might play an important role in this disease.

The post Investigating Cancer Stem Cells with the S3™ Cell Sorter first appeared on Bio-Radiations.]]> Using Droplet Digital™ PCR to Monitor Environmental Contaminants in Water https://www.bioradiations.com/using-droplet-digital-pcr-to-monitor-environmental-contaminants-in-water/ Wed, 15 Oct 2014 19:00:10 +0000 http://www.bioradiations.com/?p=4436 South of Los Angeles, near some of America’s most famous beaches, one small agency is working on new methods for coastal water monitoring. Watch this video and see how scientists from SCCWRP, the Southern California Coastal Water Research Project, are using Droplet Digital PCR to watch over swimmer safety and ensure a clean environment.

The post Using Droplet Digital™ PCR to Monitor Environmental Contaminants in Water first appeared on Bio-Radiations.]]> Protecting Coastal Ecosystems with Droplet Digital™ PCR https://www.bioradiations.com/protecting-coastal-ecosystems-with-droplet-digital-pcr/ Tue, 14 Oct 2014 19:00:24 +0000 http://www.bioradiations.com/?p=2025 Who’s watching over swimmer safety at America’s beaches? Go inside one agency tasked with pioneering new methods for water quality monitoring, and see how its scientists are employing Droplet Digital PCR technology to check coastal waters for harmful pathogens.

The post Protecting Coastal Ecosystems with Droplet Digital™ PCR first appeared on Bio-Radiations.]]> Using the ChemiDoc Touch Imaging System to Find Leukemia Targets at UCSF https://www.bioradiations.com/using-the-chemidoc-touch-imaging-system-to-find-leukemia-targets-at-ucsf/ Thu, 09 Oct 2014 00:50:18 +0000 http://www.bioradiations.com/?p=733 Discover how researcher Ernesto Diaz-Flores uses the ChemiDoc Touch Imaging System as he investigates therapeutic targets for a subtype of childhood leukemia. An avid photographer, Diaz-Flores also talks about the ...

The post Using the ChemiDoc Touch Imaging System to Find Leukemia Targets at UCSF first appeared on Bio-Radiations.]]> Bio-Rad’s S3 Cell Sorter Development: Redesigning Cell Sorting Technology https://www.bioradiations.com/bio-rads-s3-cell-sorter-development-redesigning-cell-sorting-technology/ Wed, 08 Oct 2014 00:54:43 +0000 http://www.bioradiations.com/?p=735 Take a look into the development of Bio-Rad’s S3 Cell Sorter, and see the fresh approach to cell sorting technology that resulted in an innovative new design.

The post Bio-Rad’s S3 Cell Sorter Development: Redesigning Cell Sorting Technology first appeared on Bio-Radiations.]]> Modeling Natural Killer Cell Receptors with the NGC Chromatography System https://www.bioradiations.com/modeling-natural-killer-cell-receptors-with-the-ngc-chromatography-system/ Tue, 07 Oct 2014 00:58:37 +0000 http://www.bioradiations.com/?p=738 See how researcher Petr Novák, a structural biologist in Prague, Czech Republic, has accelerated his effort to characterize complex receptor molecules by integrating the NGC chromatography system into his lab’s ...

The post Modeling Natural Killer Cell Receptors with the NGC Chromatography System first appeared on Bio-Radiations.]]> Telling the Story of Western Blots with the ChemiDoc Touch Imaging System https://www.bioradiations.com/telling-the-story-of-three-western-blots-with-the-chemidoc-touch-imaging-system/ Wed, 13 Aug 2014 01:55:55 +0000 http://www.bioradiations.com/?p=618 For a long time X-ray film has been the standard for imaging western blots, but this method has its limitations. Find out how 3 researchers are using the digital tools offered by the new ChemiDoc Touch Imaging System to beat these limitations and improve their blot images.

The post Telling the Story of Western Blots with the ChemiDoc Touch Imaging System first appeared on Bio-Radiations.]]> Genomic Variation Analysis with Droplet Digital PCR: Success Stories https://www.bioradiations.com/genomic-variation-analysis-with-droplet-digital-pcr-success-stories/ Tue, 10 Jun 2014 22:38:18 +0000 http://www.bioradiations.com/?p=1024 Researchers are having success applying Droplet Digital PCR (ddPCR™) technology across many different fields. Here are two such success stories, one involving the application of ddPCR in detecting mutations in iPS cells, the other in predicting allele-specific variation in human brain development.

The post Genomic Variation Analysis with Droplet Digital PCR: Success Stories first appeared on Bio-Radiations.]]> Unlocking the Structures of Natural Killer Cell Receptors with the NGC™ Chromatography System https://www.bioradiations.com/unlocking-the-structures-of-natural-killer-cell-receptors-with-the-ngc-chromatography-system/ Tue, 08 Apr 2014 20:54:47 +0000 http://www.bioradiations.com/?p=1073 Structural biologist Petr Novák employs the latest techniques to model natural killer cell receptor molecules, research that may one day result in powerful therapies to treat cancer and infections. Go inside the fascinating world of structural characterization and find out how Novák has integrated the NGC™ chromatography system into his effort to visualize these molecules in vivid detail.

The post Unlocking the Structures of Natural Killer Cell Receptors with the NGC™ Chromatography System first appeared on Bio-Radiations.]]> Transforming Cancer Research: Droplet Digital PCR Plays Integral Role at Fred Hutchinson Cancer Research Center https://www.bioradiations.com/transforming-cancer-research-droplet-digital-pcr-plays-integral-role-at-fred-hutchinson-cancer-research-center/ Tue, 11 Mar 2014 20:11:22 +0000 http://www.bioradiations.com/?p=1008 Droplet Digital PCR has major implications for cancer studies, where the ability to accurately measure biomarkers may result in important insights into cancer genesis and progression. Find out about new findings on micro RNA and Tumor Infilitrating Lymphocytes made possible by ddPCR technology.

The post Transforming Cancer Research: Droplet Digital PCR Plays Integral Role at Fred Hutchinson Cancer Research Center first appeared on Bio-Radiations.]]> Profiling Dynamic Cancer Drug Responses with BioMarker Strategies, LLC and the Bio-Plex® Multiplex Immunoassay System https://www.bioradiations.com/profiling-dynamic-cancer-drug-responses-with-biomarker-strategies-llc-and-the-bio-plex-multiplex-immunoassay-system/ Tue, 11 Feb 2014 19:45:15 +0000 http://www.bioradiations.com/?p=1199 In an age of personalized medicine, getting the most out of highly targeted cancer therapies takes finding the best molecular targets for each patient. BioMarker Strategies LLC, a small startup, has been developing an innovative method to do this by modeling oncogenic pathway responses, but they needed to accurately measure the levels of phosphoproteins resulting from the activation of these genes. Learn how they are using the Bio-Plex multiplex immunoassay system to accurately quantify the proteins and generate functional signaling profiles for these oncogenes.

The post Profiling Dynamic Cancer Drug Responses with BioMarker Strategies, LLC and the Bio-Plex® Multiplex Immunoassay System first appeared on Bio-Radiations.]]> Microbes in Space! High School Students Design Experiments for the International Space Station with Bio-Rad’s pGLO™ Bacterial Transformation Kits https://www.bioradiations.com/microbes-in-space-high-school-students-design-experiments-for-the-international-space-station-with-bio-rads-pglo-bacterial-transformation-kits/ Tue, 10 Dec 2013 22:57:32 +0000 http://www.bioradiations.com/?p=1496 Retired satellite engineer Dan Saldana is helping Valley Christian High School in San Jose, CA build a program to send student experiments to the International Space Station. To study microbial growth in microgravity, Saldana and his students turned to Bio-Rad’s pGLO bacterial transformation kits. Learn about the high-flying travels of these glowing bacteria and the science learning that resulted.

The post Microbes in Space! High School Students Design Experiments for the International Space Station with Bio-Rad’s pGLO™ Bacterial Transformation Kits first appeared on Bio-Radiations.]]> The Chromatography Chronicles Part 5: Chromatography You Can Count On https://www.bioradiations.com/the-chromatography-chronicles-part-5-chromatography-you-can-count-on/ Wed, 13 Nov 2013 00:08:08 +0000 http://www.bioradiations.com/?p=1140 In biochromatography, every purification or separation procedure that fails because of instrument malfunction wastes precious lab resources. That’s why Bio-Rad, in designing the NGC chromatography system, found new ways to engineer reliability into the chromatography experience. Here’s how they did it.

The post The Chromatography Chronicles Part 5: Chromatography You Can Count On first appeared on Bio-Radiations.]]> Stand Up Against Downtime https://www.bioradiations.com/stand-up-against-downtime/ Mon, 11 Nov 2013 20:00:17 +0000 http://www.bioradiations.com/?p=2168 Facing adversity with humor, some chromatographers are drawing on the healing power of laughter to deal with the frustrations of chromatography systems that just won’t work.

The post Stand Up Against Downtime first appeared on Bio-Radiations.]]> Learning Curve Blues https://www.bioradiations.com/learning-curve-blues/ Tue, 08 Oct 2013 19:00:18 +0000 http://www.bioradiations.com/?p=2181 This researcher sings a tune many will recognize from their own frustrations with overly complex chromatography instruments. The NGC™ chromatography system offers a simple, user-friendly interface so even students with little experience will beat the “learning curve blues.”

The post Learning Curve Blues first appeared on Bio-Radiations.]]> The Chromatography Chronicles Part 4: Chromatography’s Intuitive Side https://www.bioradiations.com/the-chromatography-chronicles-part-4-chromatographys-intuitive-side/ Wed, 02 Oct 2013 22:24:10 +0000 http://www.bioradiations.com/?p=1132 Chromatography instruments have a bad reputation in terms of their complexity and difficulty of use. In response, Bio-Rad’s designers and engineers challenged themselves to make the new NGC™ chromatography system as simple and intuitive-to-use as possible. Learn about the new easier-to-use instrument interface they created as a result.

The post The Chromatography Chronicles Part 4: Chromatography’s Intuitive Side first appeared on Bio-Radiations.]]> Breaking Leukemia’s Limits of Detection with Droplet Digital™ PCR https://www.bioradiations.com/breaking-leukemias-limits-of-detection-with-droplet-digital-pcr-video/ Mon, 16 Sep 2013 21:13:12 +0000 http://www.bioradiations.com/?p=2187 Prof. Alec Morley, a pioneer in digital PCR, describes his use of Droplet Digital PCR (ddPCR™) technology to advance the diagnosis and treatment of leukemia. Morley and his colleagues at Flinders University and Medical Center in Adelaide, South Australia previously developed a digital PCR method for the early detection of residual acute lymphoblastic leukemia (ALL). Learn how Morley is now using Bio-Rad's ddPCR technology to develop a diagnostic test for monitoring chronic myeloid leukemia.

The post Breaking Leukemia’s Limits of Detection with Droplet Digital™ PCR first appeared on Bio-Radiations.]]> Breaking Leukemia’s Limits of Detection with Droplet Digital PCR https://www.bioradiations.com/breaking-leukemias-limits-of-detection-with-droplet-digital-pcr/ Wed, 11 Sep 2013 05:11:54 +0000 http://www.bioradiations.com/?p=524 In the early 1990s, researcher Alec Morley and his colleagues pioneered digital PCR techniques to measure acute lymphoblastic leukemia. Today, Morley is trying to develop a more accurate way to quantify chronic myeloid leukemia. Find out why he chose Bio-Rad’s Droplet Digital PCR technology for this effort.

The post Breaking Leukemia’s Limits of Detection with Droplet Digital PCR first appeared on Bio-Radiations.]]> Bench Buzz – Protein Purification Product Testers https://www.bioradiations.com/bench-buzz-protein-purification-product-testers/ Tue, 10 Sep 2013 19:00:32 +0000 http://www.bioradiations.com/?p=2205 Meet Janna and Tomas. After hearing competing claims about the scalability of next-generation chromatography systems, this dynamic duo took it upon themselves to discover the truth. Now let's face it, when you think of protein purification you don't usually think of good times. But somehow Janna and Tomas manage to keep the mood light even as they put the systems to the test by simulating changing protein purification needs. Their conclusion? Vote Yes for Better Chromatography. Vote Yes for Bio-Rad.

The post Bench Buzz – Protein Purification Product Testers first appeared on Bio-Radiations.]]> The Chromatography Chronicles Part 3: Adding, Swapping, and Scaling — Better Chromatography through Modular Design https://www.bioradiations.com/the-chromatography-chronicles-part-3-adding-swapping-and-scaling-better-chromatography-through-modular-design/ Tue, 10 Sep 2013 18:11:57 +0000 http://www.bioradiations.com/?p=1119 What does it take to configure your own chromatography system? Part three of The Chromatography Chronicles examines how the NGC™ chromatography system adapts and grows to meet changing lab needs, and the modular design that makes this possible.

The post The Chromatography Chronicles Part 3: Adding, Swapping, and Scaling — Better Chromatography through Modular Design first appeared on Bio-Radiations.]]> Buying a New Preparative Protein Purification System – You Have a New Choice https://www.bioradiations.com/buying-a-new-preparative-protein-purification-system-you-have-a-new-choice/ Tue, 13 Aug 2013 19:00:44 +0000 http://www.bioradiations.com/?p=2222 A day in the life of Maria, a post-graduate scientist. Both Maria and her PI are annoyed with their unreliable, out-dated protein purification system, and her PI asks Maria to buy them a new one. She struggles to find a system that meets all their needs until she remembers that Bio-Rad has a new next-generation chromatography system that will work for everyone!

The post Buying a New Preparative Protein Purification System – You Have a New Choice first appeared on Bio-Radiations.]]> The Chromatography Chronicles Part 2: The Chromatographers Who Came in from the Cold https://www.bioradiations.com/the-chromatography-chronicles-part-2-the-chromatographers-who-came-in-from-the-cold/ Tue, 13 Aug 2013 18:00:03 +0000 http://www.bioradiations.com/?p=1111 Is spending hours in the coldroom just an inevitable part of doing chromatography? The engineers and designers at Bio-Rad believed that, with a little innovation, the answer could be “no.” Part two of The Chromatography Chronicles reveals how they freed the NGC™ medium-pressure chromatography system — and its users — from the coldroom’s chilly confines.

The post The Chromatography Chronicles Part 2: The Chromatographers Who Came in from the Cold first appeared on Bio-Radiations.]]> Vote Yes for Better Chromatography — The Results Are In! https://www.bioradiations.com/vote-yes-for-better-chromatography-the-results-are-in/ Tue, 09 Jul 2013 19:00:16 +0000 http://www.bioradiations.com/?p=2231 Watch the protein purification election night special parody! Find out which chromatography system wins. Laugh Out Loud at the terrible protein purification "pundit" and Vote Yes for Better Chromatography "Fanatics." Learn what values and system features were appreciated most by voters.

The post Vote Yes for Better Chromatography — The Results Are In! first appeared on Bio-Radiations.]]> The Chromatography Chronicles Part 1: The Votes Are in — Customer Voices and the NGC Chromatography System Design Process https://www.bioradiations.com/the-chromatography-chronicles-part-1-the-votes-are-in-customer-voices-and-the-ngc-chromatography-system-design-process/ Tue, 09 Jul 2013 17:47:34 +0000 http://www.bioradiations.com/?p=1107 Whether through unreliability, lack of workflows, or poor design, chromatography systems can cause major hassles for any lab involved in purifying proteins. Would Bio-Rad be able to solve these longstanding problems? This new series takes an inside look at the development of the NGC medium-pressure chromatography system. This month: bringing customers into the design process.

The post The Chromatography Chronicles Part 1: The Votes Are in — Customer Voices and the NGC Chromatography System Design Process first appeared on Bio-Radiations.]]> Revealing BRCA2 Pathways in Cancer with Bio-Rad’s V3 Western Workflow™ https://www.bioradiations.com/revealing-brca2-pathways-in-cancer-with-bio-rads-v3-western-workflow-video/ Thu, 13 Jun 2013 19:00:34 +0000 http://www.bioradiations.com/?p=2233 Research led by Prof. Ryan Jensen at Yale Medical School focuses on elucidating the links between BRCA gene mutations and breast cancer. Learn how researchers in his lab use Bio-Rad's V3 Western Workflow to study interactions between BRCA proteins and the DNA repair protein RAD51. Understanding how these proteins interact in carcinogenesis and tumor growth will provide a new understanding of breast cancer mechanisms that could lead to new therapies.

The post Revealing BRCA2 Pathways in Cancer with Bio-Rad’s V3 Western Workflow™ first appeared on Bio-Radiations.]]> T100™ Thermal Cycler – Endorsed by Customers around the World https://www.bioradiations.com/t100-thermal-cycler-endorsed-by-customers-around-the-world/ Thu, 25 Apr 2013 19:00:20 +0000 http://www.bioradiations.com/?p=2235 Life science researchers all over the world use the T100 thermal cycler in their daily routine. In this video, users describe how it saves them time and helps them consistently obtain high-quality data.

The post T100™ Thermal Cycler – Endorsed by Customers around the World first appeared on Bio-Radiations.]]> Learning in their DNA: Inside the Bio-Rad Science Ambassador Program https://www.bioradiations.com/learning-in-their-dna-inside-the-bio-rad-science-ambassador-program/ Tue, 12 Mar 2013 18:17:27 +0000 http://www.bioradiations.com/?p=1565 Take a closer look at Bio-Rad's initiative to bring scientists into K–12 schools in North America by following three Ambassadors as they go into classrooms. Find out more about what this program offers students, teachers, and researchers.

The post Learning in their DNA: Inside the Bio-Rad Science Ambassador Program first appeared on Bio-Radiations.]]> Investigating Protein Translation with the NGC™ Chromatography System https://www.bioradiations.com/investigating-protein-translation-with-the-ngc-chromatography-system/ Thu, 14 Feb 2013 20:00:55 +0000 http://www.bioradiations.com/?p=2237 The Fraser lab at University of California Davis tested Bio-Rad’s NGC system for the purification of ribosomal complex proteins in their studies of protein translation mechanisms. The NGC system enabled these researchers to significantly increase their protein purification throughput and save valuable time in the lab.

The post Investigating Protein Translation with the NGC™ Chromatography System first appeared on Bio-Radiations.]]> Investigating Protein Translation with Bio-Rad’s NGC Chromatography System https://www.bioradiations.com/investigating-protein-translation-with-bio-rads-ngc-chromatography-system/ Fri, 08 Feb 2013 04:51:44 +0000 http://www.bioradiations.com/?p=666 The Fraser Laboratory in the Dept. of Molecular and Cellular Biology at UC Davis studies protein translation mechanisms by purifying diverse ribosomal proteins and reconstructing the translation complex in vitro. The lab utilized Bio-Rad’s NGC system to overcome specific purification difficulties with their protein while beta-testing the equipment. The NGC system enabled the group to increase their throughput by 25% and also saved substantial training time.

The post Investigating Protein Translation with Bio-Rad’s NGC Chromatography System first appeared on Bio-Radiations.]]> Amplifying in the Outback: Researcher Brings Real-Time PCR to Australia’s Kimberley Wilderness https://www.bioradiations.com/amplifying-in-the-outback-researcher-brings-real-time-pcr-to-australias-kimberley-wilderness/ Mon, 04 Feb 2013 21:22:23 +0000 http://www.bioradiations.com/?p=3294 Dr. Tim Inglis of the University of Western Australia seeks better ways to conduct surveillance and respond to outbreaks of tropical infectious diseases. For over a decade he’s been developing detection assays for a slate of pathogens. Find out how Bio-Rad’s MiniOpticon Real-Time PCR system allows him to effectively run these assays in such remote locations as the Kimberley Wilderness in Australia’s Top End.

The post Amplifying in the Outback: Researcher Brings Real-Time PCR to Australia’s Kimberley Wilderness first appeared on Bio-Radiations.]]> ChemiDoc™ MP Imaging System Testimonial — KAIST, South Korea (full version) https://www.bioradiations.com/chemidoc-mp-imaging-system-testimonial-kaist-south-korea-full-version/ Wed, 14 Nov 2012 20:00:03 +0000 http://www.bioradiations.com/?p=2239 Learn how scientists in the Gene Regulation Laboratory at the Korea Advanced Institute of Science and Technology (KAIST) use the ChemiDoc MP imaging system in their work investigating the molecular machinery involved in epigenetic gene regulation.

The post ChemiDoc™ MP Imaging System Testimonial — KAIST, South Korea (full version) first appeared on Bio-Radiations.]]> TGX Stain-Free™ Precast Gels Facilitate LDL Research on Potential New Drug Targets https://www.bioradiations.com/tgx-stain-free-precast-gels-facilitate-ldl-research-on-potential-new-drug-targets/ Mon, 01 Oct 2012 17:53:48 +0000 http://www.bioradiations.com/?p=1057 When Dr. Fred Bauzon started his research, he worked with bioinformatics specialists to functionalize suitable gene candidates based on their expression levels with HMGCR transcript levels. All his experiments demonstrated a reduction in low-density lipoprotein receptor protein (LDLR) and candidate gene protein levels after the candidate gene was silenced. Here Bauzon discusses how TGX Stain-free precast gels have aided his research toward future drug targets for the therapeutic control of LDL uptake.

The post TGX Stain-Free™ Precast Gels Facilitate LDL Research on Potential New Drug Targets first appeared on Bio-Radiations.]]> ChemiDoc™ MP Imaging System Testimonial — Erlangen, Germany (full version) https://www.bioradiations.com/chemidoc-mp-imaging-system-testimonial-erlangen-germany-full-version/ Fri, 14 Sep 2012 19:00:29 +0000 http://www.bioradiations.com/?p=2241 Learn how scientists in the Department of Animal Physiology at the University of Erlangen in Erlangen, Germany use the ChemiDoc MP imaging system in their work investigating sensory systems, in particular, the eye.

The post ChemiDoc™ MP Imaging System Testimonial — Erlangen, Germany (full version) first appeared on Bio-Radiations.]]> High Sensitivity of Bio-Plex® Multiplex System is Key in Study for Novel Melanoma Therapeutics https://www.bioradiations.com/high-sensitivity-of-bio-plex-multiplex-system-is-key-in-study-for-novel-melanoma-therapeutics/ Wed, 15 Aug 2012 21:43:36 +0000 http://www.bioradiations.com/?p=1176 alt

Melanoma is an aggressive cancer where early detection is essential for patient survival. The Facchiano lab is developing new anti-proliferation molecules against melanoma and is working to identify new molecular markers at the very early stages of pathology. Here Dr Antonio Facchiano discusses the merits of using the Bio-Plex technology to measure dose-dependent changes in expression levels of growth and angiogenic factors in cell lysates and supernatants.

The post High Sensitivity of Bio-Plex® Multiplex System is Key in Study for Novel Melanoma Therapeutics first appeared on Bio-Radiations.]]> Bio-Plex® Multiplex System is Key in Novel Melanoma Therapeutics Study https://www.bioradiations.com/bio-plex-multiplex-system-is-key-in-novel-melanoma-therapeutics-study/ Wed, 15 Aug 2012 19:00:33 +0000 http://www.bioradiations.com/?p=2245 Researchers at the Immaculate Dermopathic Institute (IDI-IRCCS, Rome) are using Bio-Plex technology in developing new anti-proliferation molecules and markers at the early stages of melanoma pathology. Dr Antonio Facchiano discusses how Bio-Plex has expedited the lab’s research.

The post Bio-Plex® Multiplex System is Key in Novel Melanoma Therapeutics Study first appeared on Bio-Radiations.]]> QX100™ Droplet Digital™ ddPCR™ System at Sangamo BioSciences https://www.bioradiations.com/qx100-droplet-digital-ddpcr-system-at-sangamo-biosciences/ Fri, 13 Jul 2012 22:36:02 +0000 http://www.bioradiations.com/?p=2250 Researchers at Sangamo BioSciences, Inc. explain the benefits of using third generation PCR as it applies to their research in the field of personalized medicine. Watch to see the latest generation of quantitative PCR in action.

The post QX100™ Droplet Digital™ ddPCR™ System at Sangamo BioSciences first appeared on Bio-Radiations.]]> Droplet Digital PCR Opens New Perspectives in HIV Research https://www.bioradiations.com/droplet-digital-pcr-opens-new-perspectives-in-hiv-research/ Fri, 15 Jun 2012 22:42:23 +0000 http://www.bioradiations.com/?p=1040 Sangamo BioSciences, Inc., located in Richmond, California, is developing HIV therapeutics toward a functional cure using their proprietary zinc finger DNA-binding protein technology. Droplet digital PCR (ddPCR™) — or third generation PCR — offers a superior solution as it can detect target sequence within a single molecule, making it a powerful technology for low copy event detection.

The post Droplet Digital PCR Opens New Perspectives in HIV Research first appeared on Bio-Radiations.]]> Novel HRM Assays Expedite Drug Resistance Surveillance for Leprosy Research https://www.bioradiations.com/novel-hrm-assays-expedite-drug-resistance-surveillance-for-leprosy-research/ Tue, 10 Apr 2012 18:22:14 +0000 http://www.bioradiations.com/?p=3363 The significant drop in leprosy worldwide is attributed to the development of antimicrobial multidrug therapy (MDT). Resistance to rifampicin — the backbone of MDT treatment — has appeared. Controlling leprosy transmission requires routine surveillance for mutations in the drug target genes before, during, and after the course of treatment. New high resolution melt (HRM) assays offer leprosy researchers a faster, more economical method to investigate resistance targets.

The post Novel HRM Assays Expedite Drug Resistance Surveillance for Leprosy Research first appeared on Bio-Radiations.]]> Bio-Plex® System in Korea https://www.bioradiations.com/bio-plex-system-in-korea/ Wed, 14 Mar 2012 19:00:31 +0000 http://www.bioradiations.com/?p=2258 Dr Hunseok Lee of Seoul National University explains why it was advantageous for him to use the Bio-Plex system to measure cytokine levels in patients administered with the new cancer vaccine that his laboratory has developed.

The post Bio-Plex® System in Korea first appeared on Bio-Radiations.]]> Bio-Plex® System in Korea — Seeking to Improve Outcomes for Cancer Patients https://www.bioradiations.com/bio-plex-system-in-korea-seeking-to-improve-outcomes-for-cancer-patients/ Thu, 08 Mar 2012 19:21:05 +0000 http://www.bioradiations.com/?p=3386 Dr Hunseok Lee has known since childhood that he wanted to grow up to become a scientist. “You get to wear white gowns, look through a microscope at various substances so small they can’t be seen by the naked eye — those things were very attractive to me when I was young,” says Lee. But the realities of putting research into practice and translating ideas into experiments have proven far more strenuous than the young Lee anticipated.

The post Bio-Plex® System in Korea — Seeking to Improve Outcomes for Cancer Patients first appeared on Bio-Radiations.]]> Mini-PROTEAN® TGX™ Gels — Customer Testimonials https://www.bioradiations.com/mini-protean-tgx-gels-customer-testimonials/ Tue, 06 Mar 2012 20:00:15 +0000 http://www.bioradiations.com/?p=2260 Scientists from UCSD, UCD, The Salk Institute, and the University of Alabama talk about the speed, performance, and quality of electrophoresis runs using the Mini-PROTEAN TGX gels in their labs.

The post Mini-PROTEAN® TGX™ Gels — Customer Testimonials first appeared on Bio-Radiations.]]> Bio-Plex® System Bench to Bedside https://www.bioradiations.com/bio-plex-system-bench-to-bedside/ Tue, 30 Aug 2011 19:00:21 +0000 http://www.bioradiations.com/?p=2267 Watch how the Bio-Plex® suspension array system has contributed to research findings in Dr Francis Spinale and Dr Steven Kornblau's laboratories that have the potential to impact screening and treatment of disease.

The post Bio-Plex® System Bench to Bedside first appeared on Bio-Radiations.]]> Gel Doc™ EZ Imaging System Customer Testimonial https://www.bioradiations.com/gel-doc-ez-imaging-system-customer-testimonial/ Mon, 29 Aug 2011 19:00:39 +0000 http://www.bioradiations.com/?p=2269 Harvard Medical School Postdoctoral student Sririam Kosuri explains how the Gel Doc EZ system has changed the way researchers image gels in the George Church lab at Harvard Medical School’s Wyss Institute.

The post Gel Doc™ EZ Imaging System Customer Testimonial first appeared on Bio-Radiations.]]> Gel Doc™ EZ Testimonial — UCSD https://www.bioradiations.com/gel-doc-ez-testimonial-ucsd/ Sun, 28 Aug 2011 19:00:28 +0000 http://www.bioradiations.com/?p=2271 Assistant Project Scientist Dr. Dorota Krawczyk, PhD, at the Geoff Rosenfeld Laboratory at the University of California, San Diego, describes how easy it is to use the Gel Doc EZ system.

The post Gel Doc™ EZ Testimonial — UCSD first appeared on Bio-Radiations.]]> Identifying Cardiac Defect–Related Protein Signatures https://www.bioradiations.com/identifying-cardiac-defect-related-protein-signatures/ Mon, 15 Aug 2011 19:09:40 +0000 http://www.bioradiations.com/?p=3401 Identifying Cardiac Defect–Related Protein SignaturesAugust 15, 2011
"The first opportunity I had to lay my hand on a human heart I knew that was that — I knew that I wanted to know how the heart works, but more importantly, how it doesn't work," says Dr Francis Spinale, describing his inspiration to both research and treat cardiac disease. Using the Bio-Plex® suspension array system, researchers in his laboratory are discovering protein signatures that have the potential to inform decision strategies in cardiac patient treatment.

The post Identifying Cardiac Defect–Related Protein Signatures first appeared on Bio-Radiations.]]> Chemokines and Cytokines as Potential Markers for Personalizing Leukemia Treatment https://www.bioradiations.com/chemokines-and-cytokines-as-potential-markers-for-personalizing-leukemia-treatment/ Wed, 10 Aug 2011 19:00:30 +0000 http://www.bioradiations.com/?p=3305 Dr. Steven Kornblau has been on faculty at MD Anderson Cancer Center in Houston, Texas, for 20 years, where he divides his time between research into further understanding leukemia disease states, and a clinical practice where he treats a small number of patients with the disease. Recently, his laboratory used the Bio-Plex® suspension array system to discover how cytokine and chemokine profiles alone can be prognostic for patients with the disease, and therefore have to potential to assist development of personalized treatments.

The post Chemokines and Cytokines as Potential Markers for Personalizing Leukemia Treatment first appeared on Bio-Radiations.]]> Unlocking the Potential of Stem Cell Research Using the EpiQ™ Chromatin Analysis Kit https://www.bioradiations.com/unlocking-the-potential-of-stem-cell-research-using-the-epiq-chromatin-analysis-kit/ Mon, 13 Jun 2011 19:00:05 +0000 http://www.bioradiations.com/?p=2603 Bedtime stories in Dr David Schaffer's — one of today's pioneers in stem cell research — childhood home were often not standard fairy tales. With both parents in careers as biomedical researchers (his mother in drug development and clinical trials for a major pharmaceutical company and his father, in cardiovascular research and a pharmacology professor) much of the conversation as far back as Schaffer can remember centered on biology and science.

The post Unlocking the Potential of Stem Cell Research Using the EpiQ™ Chromatin Analysis Kit first appeared on Bio-Radiations.]]>