ArticlesCell BiologyResearch Highlights

Monocytes — a Mini Review

Monocytes play key roles in mediating innate and adaptive immune responses. Here is an overview of the types, functions, process of recruitment, and the role of monocytes in disease.
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ArticlesCell BiologyResearch Highlights

Macrophage Polarization — An Overview

Macrophages are important players in the phagocytosis process in the immune system. In this detailed review, we provide an overview on the different types of macrophages, the signaling molecules involved in the polarization of M1 and M2 macrophage subsets, and more.
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ArticlesReal-time qPCR/PCRResearch Highlights

So, How Can the Sso7d Fusion Polymerase Technology Help Your PCR?

During a PCR reaction, it is imperative for the DNA polymerase to remain attached to the template while extending the new strand. This association is jeopardized under challenging PCR conditions and when amplifying longer DNA fragments. See how Sso7d, a small protein capable of binding with the polymerase, helps in stabilizing this association and increasing PCR efficiency.
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ArticlesFeatured StoriesGeneral InterestResearch Highlights

Next Generation Computers: Transforming Cells into Autonomous Computing Devices

What do computers and cells have in common? Can cells function as computers or recording devices? Can a bacterial computer be built? Synthetic biologists have recently developed a platform called SCRIBE (Synthetic Cellular Recorders Integrating Biological Events) to convert genomic DNA into a “tape” for recording and memorizing information. This article explores many interesting aspects of autonomous cellular memory and the potential applications of such living computational systems.
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ArticlesGeneral InterestResearch Highlights

Researcher Profile: Suzanne Topalian Pioneers PD-1 Inhibitor Drug to Treat Advanced Cancer

Suzanne Topalian was recognized in 2014 by Nature as one of “Ten People Who Mattered This Year” for her contributions in pioneering nivolumab, a programmed cell death protein-1 (PD-1) inhibitor that was recently approved in Japan for advanced melanoma treatment and that shifts the paradigm for a wide range of cancer therapies.
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ArticlesGeneral InterestResearch Highlights

Ebola: New Techniques for Diagnosis, Treatment, and Prevention

The 2014 West African Ebola outbreak has been an unprecedented public health emergency, with thousands infected across multiple countries and cases spreading internationally. This article examines the science behind this deadly hemorrhagic fever, including its pathogenesis, detection, the challenges it presents in the field, and research into new therapies such as monoclonal antibodies.
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ArticlesElectrophoresis/Western BlottingResearch Highlights

Trends in Protein Separation and Analysis — the Advance of Stain-Free Technology

What is stain-free technology? How does it work in electrophoresis and western blotting? How does it compare with existing staining techniques? What are its advantages and possible concerns? Here is a technical review of this rapidly growing technological advance.
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ArticlesChromatographyResearch Highlights

Purification Trends: How Smart is Chromatography Automation?

What does automated protein purification mean today? What might it look like tomorrow? Bioradiations talks to a variety of users about what they’re doing now to implement automation in their purification processes, and what possibilities they envision that will improve chromatography in the near future.
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ArticlesDroplet Digital PCR (ddPCR)Research Highlights

The Ever-Expanding Universe of Droplet Digital™ PCR Applications

Bio-Rad’s groundbreaking Droplet Digital PCR technology can be applied in a variety of applications to glean precious information that cannot be obtained by any other method. Find out more about how this technology has been used in applications such as quantification of cancer biomarkers, validation of next generation sequencing, distinguishing genomic variation, and more.
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ArticlesProtein Interaction AnalysisResearch Highlights

Building New Anti-HIV Molecules with Bio-Rad’s ProteOn™ XPR36 System

Can we construct molecules that will interfere with disease pathways? Dan Mitchell of the University of Warwick and his colleagues wanted to apply new synthesis techniques to interrupting HIV infection. Find out what they learned about the potential of these novel molecules using Bio-Rad’s ProteOn™ XPR36 System.
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