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ArticlesCell Biology

Tyrosine Phosphorylation of EGF R

Growth factors are protein signaling molecules that play crucial roles in the regulation of numerous cellular processes such as proliferation, differentiation, and survival. Learn more about the phosphorylation of one such factor, the epidermal growth factor receptor (EGF R).
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Cell BiologyPast WebinarsWebinars

A 16-Color Flow Cytometry Panel to Monitor Checkpoint Inhibitor Expression and T-Cell Exhaustion Following Treatment with the PD1 Inhibitor Nivolumab

Presented by: Angie Green, PhD, Senior Scientist

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We discuss using a multiparameter flow cytometry panel to monitor T-cell exhaustion states and the expression of checkpoint inhibitors. We used an in vitro model; however, the panel is designed to be compatible with clinical samples to monitor immunotherapy.

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R-Loops in Cancer Research
ArticlesCell BiologyDrug Discovery and Development

R-Loops and Their Key Role in Cancer Research

R-loops are being investigated as potential therapeutic targets for cancer. Find out what they are, how they form, how their formation is controlled by our cells, and, above all, their potential as therapeutic targets.
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Cell BiologyPast WebinarsWebinars

To Boldly Flow: Gain Confidence to Start Flow Cytometry

Presented by: Mike Blundell, PhD, Product Manager

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Flow cytometry is a powerful technique used widely in biological research, but if you are just beginning your flow journey, it can be hard to know where to start. In this webinar, you will:

  • Learn the important steps to obtaining better flow cytometry data
  • Get advice on how to apply this knowledge to improve your experiments
  • Find out how Bio-Rad’s panel builder tool can help you design your experiments, no matter how many colors you plan to use

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Discovering Small Vesicles with Flow Cytometry
ArticlesCell BiologyFeatured Stories

Flow Cytometry — A Gateway for Discovering More about Small Vesicles

Small vesicles were identified over 50 years ago but scientists are still trying to understand their biology and role in disease. These vesicles have become relevant for monitoring, diagnosing, and treating complex diseases such as cancer. Yet, because of their small size compared to cells, they require intricate technologies to truly understand their impact in research. Learn about the various technologies used to study small vesicles and discover the power of flow cytometry for learning more about these valuable vesicles.
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Publishing Meaningful Antibody Data
ArticlesCell BiologyElectrophoresis/Western BlottingProtocols and Tips

Finding a Good Antibody:
Part III – Publish Meaningful Data

In the first two articles in our Finding a Good Antibody series, you learned how to select the best antibodies and received tips on proper antibody validation. In this third and final article, see how you can use this information to publish meaningful data when using antibodies. And get some guidelines for antibody best practices.
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Benefits of Flow Cytometry in Immuno-Oncology Research
ArticlesCell BiologyDrug Discovery and DevelopmentFeatured Stories

The Benefits of Flow Cytometry in Immuno-Oncology Research

Immuno-oncology, or cancer immunotherapy, research focuses heavily on the various types of cells and their behavior in cancer, so the use of flow cytometry to interrogate these cells is a no brainer. See how flow cytometry fits in this growing field of research and how it can help identify new targets and improve drug design to generate more effective and safer cancer therapeutics.
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Antibody Validation for Your Application
ArticlesCell BiologyElectrophoresis/Western BlottingProtocols and Tips

Finding a Good Antibody:
Part II — Antibody Validation

Finding antibodies that work for your application is just the first step in finding a good antibody. Next is antibody validation — making sure that your antibody does what you think it is supposed to. In this second article in our Finding a Good Antibody series, learn how best to go about validating your antibodies.
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Cell BiologyPast WebinarsWebinars

When Small Matters — See How the ZE5 Cell Analyzer Can Help

Presented by: Yasha Talaga, MSc, Applications and Collaborations Product Manager, Cell Biology

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In this webinar, Yasha Talaga will explain how specific methodologies and instrument setup on the ZE5 Cell Analyzer allow for reliable exosome detection data.

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Finding a Good Antibody: Part I — Selecting the Best Antibodies.
ArticlesCell BiologyElectrophoresis/Western BlottingProtocols and Tips

Finding a Good Antibody:
Part I — Selecting the Best Antibodies

Even though antibodies are central to basic research as well as drug development and diagnostics, concerns with antibody validation remain high, and finding an antibody that works well for a specific application can be quite a challenge. Use these tips to select the best antibodies for your application.
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