ArticlesBio-Plex Multiplex AssaysTechnical Reports

Bio-Plex Pro Human Inflammation Assays: Performance Data

Bio-Rad’s Bio-Plex Pro Human Inflammation Assay measures 37 of the most relevant inflammation biomarkers, including TNF superfamily proteins, Treg cytokines, IFN proteins, and matrix metalloproteinases, in a single multiplex panel.Check out the performance characteristics of the assay panel in this report.
READ MORE →
ArticlesBio-Plex Multiplex AssaysTechnical Reports

Cross-Reactivity of Bio-Plex Pro™ Human Cancer Biomarker Assays to Mouse Proteins

Mice are an optimal model organism for human cancer studies. However, when experiments involve a human xenograft in a mouse host, cross-reactivity presents a major concern in measuring biomarkers. This technical report evaluates 14 Bio-Plex Pro Human Cancer Biomarker Assays for cross reactivity to mouse proteins and discusses the resulting data.
READ MORE →
ArticlesBio-Plex Multiplex AssaysTechnical Reports

Multiplex Analysis of Cell Death Markers Using Bio-Plex Pro™ RBM Apoptosis Assays

Bio-Rad’s new Bio-Plex Pro RBM Apoptosis Multiplex Assays enable complex, quantitative analyses of biomarkers in the intrinsic apoptosis pathway. Learn more about these biomarkers and view sample data and performance characteristics of these assays in this detailed technical report.
READ MORE →
AppsBio-Plex Multiplex Assays

Bio-Plex® Assay Builder

Design your customized Express or x-Plex assay, process your catalog number, and obtain pricing information, launch the Assay Builder
READ MORE →
ArticlesBio-Plex Multiplex AssaysTechnical Reports

Applications of Bio-Plex Pro™ Cell Signaling Akt and MAPK Assay Panels in Signal Transduction Pathways

The Akt and MAPK signal transduction pathways are key areas of study for their roles in cell growth, function, and death, as well as for their possible roles in cancer development and diabetes. Bio-Rad’s new Bio-Plex Pro™ Akt and MAPK cell signaling assays enable researchers to study the activation of these key pathways as a response to various stimuli. This technical report validates the sensitivity and specificity of these assays after cells were exposed to insulin, EGF (epidermal growth factor), and UV radiation.
READ MORE →
ArticlesBio-Plex Multiplex AssaysCustomer Stories

Profiling Dynamic Cancer Drug Responses with BioMarker Strategies, LLC and the Bio-Plex® Multiplex Immunoassay System

In an age of personalized medicine, getting the most out of highly targeted cancer therapies takes finding the best molecular targets for each patient. BioMarker Strategies LLC, a small startup, has been developing an innovative method to do this by modeling oncogenic pathway responses, but they needed to accurately measure the levels of phosphoproteins resulting from the activation of these genes. Learn how they are using the Bio-Plex multiplex immunoassay system to accurately quantify the proteins and generate functional signaling profiles for these oncogenes.
READ MORE →
ArticlesBio-Plex Multiplex AssaysCustomer Stories

High Sensitivity of Bio-Plex® Multiplex System is Key in Study for Novel Melanoma Therapeutics

alt Melanoma is an aggressive cancer where early detection is essential for patient survival. The Facchiano lab is developing new anti-proliferation molecules against melanoma and is working to identify new molecular markers at the very early stages of pathology. Here Dr Antonio Facchiano discusses the merits of using the Bio-Plex technology to measure dose-dependent changes in expression levels of growth and angiogenic factors in cell lysates and supernatants.
READ MORE →
ArticlesBio-Plex Multiplex AssaysProduct Highlights

Focus on the Biology: Bio-Rad’s New Bio-Plex Data Pro™ Software Simplifies Multiplex Data Analysis

Many instruments offer multiplexing capability for biomarker measurements. But to handle and make sense of the huge amount of multiplex data requires sophisticated software like Bio-Plex Data Pro, which simplifies organization, import, sorting and visualization of data, and performing calculations and statistical analyses.
READ MORE →
ArticlesBio-Plex Multiplex AssaysTechnical Reports

Multiplex Analysis of Inflammatory Markers Using Bio-Plex Pro™ Human Th17 Cytokine Assays

The T-helper cell (Th17) pathway has been implicated in several autoimmune diseases and in cancer. New magnetic bead–based assays have been developed for several biomarkers in this pathway. The performance characteristics of these assays are evaluated from data on intra- and inter-assay precision, standard curve recovery, cross reactivity, and linearity of dilution.
READ MORE →
ArticlesBio-Plex Multiplex AssaysCustomer Stories

Bio-Plex® System in Korea — Seeking to Improve Outcomes for Cancer Patients

Dr Hunseok Lee has known since childhood that he wanted to grow up to become a scientist. “You get to wear white gowns, look through a microscope at various substances so small they can’t be seen by the naked eye — those things were very attractive to me when I was young,” says Lee. But the realities of putting research into practice and translating ideas into experiments have proven far more strenuous than the young Lee anticipated.
READ MORE →