ArticlesProtocols and Tips

Maximize Genomic Insights by Combining Molecular Profiling Methods

Dive into an in-depth exploration of the molecular methods for gene expression profiling — highlighting the strengths, applications, and uses of quantitative PCR (qPCR), Droplet Digital PCR (ddPCR), and RNA sequencing (RNA-Seq) technologies.
ArticlesBreak RoomNext-Generation Sequencing

Sequenced — Comic Series

Join Terence, a motivated undergrad, as he experiences the ups and downs of research using next-generation sequencing, learning valuable tips for successful NGS experiments along the way
Droplet Digital PCR (ddPCR) VideoVideos

Explore the Epigenomic Landscape of Single Cells with the scATAC You Seq

Gain access to high-performance chromatin profiling to unravel the complexities of cellular heterogeneity, differentiation, and disease-specific alterations in gene regulation. With single-cell ATAC-seq (assay for transposase-accessible chromatin using sequencing), you can delve into the gene regulatory landscape of individual cells, unlocking invaluable insights into the epigenomic mechanisms that shape their behavior.
ArticlesNext-Generation Sequencing

6 Key Considerations for Getting the Long and Short of RNA-Seq with FFPE Samples

When it comes to tumor profiling, the poor quality and degradation of RNA in formalin-fixed paraffin-embedded (FFPE) samples are major limitations. To overcome this challenge, we tested a novel RNA-Seq workflow using the SEQuoia Complete Library Prep Kit and the SEQuoia Ribodepletion Kit. This workflow offers more complex transcriptome profiling, including both long and short RNA biotypes, to better represent the complete transcriptome.
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Next-Generation Sequencing VideoProduct HighlightsVideos

Take the Expressway to RNA Library Prep

RNA-Seq library preparation is a manually intensive, time-consuming process prone to bias from the multiple enzymes required. So, how can you trust your sequencing results? Bio-Rad is revolutionizing RNA-Seq library prep with the SEQuoia Express Stranded RNA Library Prep Kit – a three-hour, three-tube solution eliminating the need for multiple enzymes and reducing both the number of pipetting steps and protocol time. The key is an engineered, proprietary retrotransposon called SEQzyme. With this serial template jumping, or continuous synthesis, reaction you can obtain an unbiased, stranded RNA-Seq library constructed to accurately represent both messenger and non-coding RNA from your sample.
ArticlesProduct Highlights

A Powerful Solution for NGS RNA Library Preparation

The SEQuoia Complete Stranded RNA Library Prep Kit is the newest addition to Bio-Rad’s next-generation sequencing (NGS) space. Capturing long and short RNAs and validated with FFPE and low-quality samples, see why it should be your top choice for high-performance RNA-Seq library prep.
Artificial Intelligence in Drug Development
ArticlesGeneral Interest

Artificial Intelligence in Drug Development

Artificial intelligence (AI) relies on building a model and applying it to solve a specific problem. Read how AI is being used to accelerate research and development, process development, manufacturing, and clinical trials within genomics.
ArticlesDroplet Digital PCR (ddPCR)Research Highlights

The Ever-Expanding Universe of Droplet Digital™ PCR Applications

Bio-Rad’s groundbreaking Droplet Digital PCR technology can be applied in a variety of applications to glean precious information that cannot be obtained by any other method. Find out more about how this technology has been used in applications such as quantification of cancer biomarkers, validation of next generation sequencing, distinguishing genomic variation, and more.