Alzheimer’s Disease: A Smoking Gun with No Suspect
ArticlesDrug Discovery and DevelopmentFeatured Stories

Alzheimer’s Disease: A Smoking Gun with No Suspect

For the past 30 years, there has been one assumed culprit of Alzheimer’s disease (AD) — beta-amyloid. However, researchers have been unsuccessful in developing effective therapies targeting this protein. Understand the history of AD and beta-amyloid and see what other biomarkers are being investigated as potential therapeutic targets.
Six Tips to Improve Your Co-IP Results
ArticlesElectrophoresis/Western BlottingProtocols and Tips

Six Tips to Improve Your Co-IP Results

Co-immunoprecipitation (co-IP) is a great way to identify target protein complexes and interacting partners. Though the technique can be highly informative, it is also challenging to master. The six tips and protocol outlined in this article will help you achieve successful co-IP results.
ArticlesChromatographyTechnical Reports

Single-Step Influenza and Dengue Virus Purification with Mixed-Mode CHT Ceramic Hydroxyapatite XT Media

See how you can use CHT XT Mixed-Mode Media to recover over 75% of your virus in a single purification step. All this while reducing contaminating proteins by over 90% and removing over 60% of dsDNA. Get simple, fast, and reproducible viral purification with CHT XT.
Bio‑Plex® Multiplex Immunoassay Technology Overview and Setting Up to Run an Assay
Bio-Plex Multiplex AssaysUpcoming WebinarsWebinars

Bio-Plex Manager Software Overview

Presented by: Brett Houser, Bio-Plex Multiplex Immunoassay Product Manager, Protein Quantitation Group
Date: Wednesday, October 17, 2018
Time: 11 AM, U.S. Pacific time

Bio-Plex Manager Software is a powerful, intuitive tool used to generate and analyze xMap data. In this webinar you will:

  • Learn how to create an assay protocol
  • Learn how to acquire data
  • Understand basic software parameters
  • Learn about general functionality and navigation
  • Master optimization of standard curves and export data for further analysis

Cell BiologyUpcoming WebinarsWebinars

A 16-Color Flow Cytometry Panel to Monitor Checkpoint Inhibitor Expression and T-Cell Exhaustion Following Treatment with the PD1 Inhibitor Nivolumab

Presented by: Angie Green, PhD, Senior Scientist
Date: Tuesday, November 6, 2018
Time: 8 AM and 4 PM U.S. Pacific time
4 PM Greenwich mean time
8 AM Singapore time (November 7)

We discuss using a multiparameter flow cytometry panel to monitor T-cell exhaustion states and the expression of checkpoint inhibitors. We used an in vitro model; however, the panel is designed to be compatible with clinical samples to monitor immunotherapy.

Nuvia HP-Q
ChromatographyUpcoming WebinarsWebinars

Large Biomolecule Purification with a New High-Performance Anion Exchange Resin

Presented by: Hana Kim, PhD, Global Product Manager, Process Chromatography
Jiali Liao, PhD, Principal Scientist, Process Chromatography

View on demand

Learn about Nuvia HP-Q Resin, a new rigid bead engineered with large pores and optimized surface extenders to deliver both high binding capacity and high recovery at high flow rates. It is ideal for large molecule purification, including plasma proteins, viruses, and VLPs.

ChromatographyUpcoming WebinarsWebinars

A New Mixed-Mode Media for Downstream Purification

Presented by: Daniel Yoshikawa, PhD, Global Product Manager, Process Chromatography
Mark A. Snyder, PhD, R&D Applications Manager, Process Chromatography

View on demand

Watch this webinar to learn about a new mixed-mode chromatography media used to purify biomolecules at process scale. It delivers unique selectivity and robust, uniformly sized beads with excellent pressure-flow properties ideal for bioprocess applications.

Novel Biomarkers for Traumatic Brain Injury
ArticlesDrug Discovery and DevelopmentFeatured Stories

Traumatic Brain Injury — A Controversial and Deadly Epidemic

Ever wonder how football is linked to degenerative brain disease? Find out here. Also, learn about novel biomarkers for traumatic brain injury (TBI), the current state of TBI research, and promising new approaches for developing a robust diagnostic tool. Discover tests currently used to diagnose TBI and read about unusual techniques used to develop reliable biomarkers.
R-Loops in Cancer Research
ArticlesCell BiologyDrug Discovery and Development

R-Loops and Their Key Role in Cancer Research

R-loops are being investigated as potential therapeutic targets for cancer. Find out what they are, how they form, how their formation is controlled by our cells, and, above all, their potential as therapeutic targets.
Bioinformatics and Our Microbiome
ArticlesDrug Discovery and DevelopmentPodcasts

Say Hello to Your Littlest Friends — the Microbiota

How well do you understand your microbiota? Dr. Allyson Byrd of Genentech, the fourth guest on Brilliant Science, is a bioinformatician focusing on parsing all the data our microbiomes have to offer. Read about the value of analyzing microbiota and how Dr. Byrd hopes to leverage the results.