ArticlesCell BiologyDrug Discovery and DevelopmentFeatured StoriesGeneral Interest

Speed Time to Results by Incorporating Flow Cytometry into the CRISPR‑Cas9 Gene Editing Workflow

The power to edit a gene is the power to change its function, and with it the biology of a cell. From generating novel cell lines and better animal models for the discovery and preclinical phases of therapeutic research to actually creating a therapeutic itself, CRISPR gene editing is allowing science to advance rapidly. See how enrichment and cell sorting can help generate edited cells faster and more reliably.
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ArticlesGeneral InterestGeneral Interest Video

Discover the Technology behind Bio-Rad’s Custom Recombinant Antibodies

See inside Bio-Rad’s custom antibody facility and learn how specific antibody requirements can become a reality through the use of Human Combinatorial Antibody Library (HuCAL®) technology for specialized custom antibodies.
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The Importance of In Vitro Assays in the Development of Biosimilars
ArticlesDrug Discovery and DevelopmentGeneral InterestPodcasts

The Importance of In Vitro Assays in the Development of Biosimilars

In this podcast, biosimilar expert, Amanda Turner, provides an in-depth explanation of the various in vitro assays used in biosimilar development and the importance of choosing the right assay type and components to achieve success.
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ArticlesDrug Discovery and DevelopmentFeatured StoriesGeneral Interest

Understanding Biomarkers for Better Drug Discovery and Development

Biomarker intelligence comes from understanding the biomarker landscape, that is, the characteristics and features of biomarkers, and disease pathways. This understanding, in turn, helps to recognize the utility of biomarkers. In this study, we partnered with Amplion Inc., to investigate biomarker usage in 24 immunotherapy companies. We found the most popular biomarkers and learnt how they are being used by each company.
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ArticlesDrug Discovery and DevelopmentFeatured StoriesGeneral Interest

Biosimilars. Are They Ready for Primetime?

Is the hype surrounding biosimilars real or simply a hopeful view on an exceedingly expensive drug market? Read this article to find out more about biosimilars and understand the challenges facing the biosimilars industry.
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ArticlesCell BiologyGeneral Interest

Understanding the Eukaryotic Cell Cycle

The eukaryotic cell cycle is an evolutionarily conserved process that results in the replication of cells. Read this mini review to better understand the eukaryotic cell cycle and get an overview of common molecular techniques used to evaluate proliferating cells.
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ArticlesChromatographyFeatured StoriesGeneral Interest

Modern Improvements to Classic Technologies: Innovating Electrophoresis and Chromatography Upstream of Protein Characterization to Speed Up Research

When testing new drug therapies, it is essential to know the identity of the protein being tested. Chromatography is a commonly used technique to separate complex biological mixtures and isolate proteins of interest prior to downstream characterization. Learn more about how automating chromatography and stain-free technology are helping to save time and effort in protein purification.
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ArticlesDrug Discovery and DevelopmentFeatured StoriesGeneral Interest

What Pharma Is Doing to Triple Clinical Trial Successes

The typical success rate of a clinical trial is less than ten percent. Pharmaceutical companies are using a variety of methods to save time and reduce costs to get drugs to market faster. Biomarker screening is proving to be an effective way to improve the drug discovery and development process. See one of the ways Pharma companies can identify the most relevant biomarkers.
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ArticlesElectrophoresis/Western BlottingGeneral Interest

Validating Antibodies — the Good, the Bad, and the Necessary

Despite the fact that antibodies are one of the most frequently used tools in life science and clinical research, there are no universally accepted guidelines to ensure that they have been properly validated. Learn about the issues facing researchers and what antibody suppliers and researchers can do to ensure that the research being carried out is trustworthy and is helping to improve overall data quality.
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ArticlesDroplet Digital PCR (ddPCR)General Interest

Rapid, Sensitive Cancer Biomarker Screening in cfDNA

Disease-associated mutations can be prognostic of outcome and inform treatment choices. However, traditional tissue biopsies limit the ability to implement personalized treatments. Read about how multiplex digital PCR can enable the tracking of treatment efficacy using liquid biopsies.
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