ArticlesDroplet Digital PCR (ddPCR)General InterestResearch Highlights

Advancing Molecular Diagnostics for Myelodysplastic Syndrome

No patient who has survived cancer wants to hear that they’ve relapsed. But hearing it sooner rather than later can dramatically increase the chances of finding a successful, potentially life-saving treatment. Using next-generation sequencing and Droplet Digital PCR, researchers at the University of Uppsala aim to detect relapse by monitoring patient-specific biomarkers. Read about their ongoing clinical study.
ArticlesCell BiologyResearch Highlights

How FACS, Genetic Screens, and the HAP1 Cell Line Uncover the Biological Mechanisms of Cancer

Genetic screens are powerful tools for finding genes associated with a particular phenotype. They play an especially important role in cancer research and are leveraged to identify predictive biomarkers that can be used to improve treatment efficacy or trace the progression of genetic alterations that ultimately lead to disease. The HAP1 cancer cell line model and fluorescence-activated cell sorting (FACS) bring efficiency to the development of genetic screens that is making them a force to be reckoned with.
EGFR signaling Bio-Rad Bioradiations banner
ArticlesCell Biology

Tyrosine Phosphorylation of EGF R

Growth factors are protein signaling molecules that play crucial roles in the regulation of numerous cellular processes such as proliferation, differentiation, and survival. Learn more about the phosphorylation of one such factor, the epidermal growth factor receptor (EGF R).
Moving Forward with Immunotherapies for Cancer
ArticlesDrug Discovery and DevelopmentFeatured Stories

Moving Forward with Immunotherapies for Cancer

Frost & Sullivan, a business consulting firm involved in market research and analysis, conducted a thought leadership forum that brought together experts in the field of immuno-oncology. Follow their discussions about the current state of immunotherapies and the key challenges and future approaches to the targeted use of the immune system in cancer treatment.
R-Loops in Cancer Research
ArticlesCell BiologyDrug Discovery and Development

R-Loops and Their Key Role in Cancer Research

R-loops are being investigated as potential therapeutic targets for cancer. Find out what they are, how they form, how their formation is controlled by our cells, and, above all, their potential as therapeutic targets.
Cancer in the Age of Long Noncoding RNA Discovery.
ArticlesFeatured StoriesGeneral Interest

Cancer in the Age of Long Noncoding RNA Discovery

Cancer is one of the leading causes of death in the world and, due to an aging population, more and more people are diagnosed with cancer every year. Researchers are actively searching for treatment options in the form of potential biomarkers. Long noncoding RNAs (lncRNAs) have piqued the interest of researchers as a relatively new source of therapeutics. Learn more about lncRNAs and see how they can be used in cancer diagnosis and intervention.