ArticlesChromatographyReal-time qPCR/PCR

Nature’s Lipid Nanoparticles: Challenges and Opportunities in Isolation and Analysis of Extracellular Vesicles

In nature, mammalian extracellular vesicles (EVs) are vital for intercellular communication, immune responses, and cell removal. EVs also hold promise in diagnostics, therapeutics, and vaccine delivery due to their abundance and natural role as carriers. Explore how overcoming challenges in EV purification and precise RNA analysis methods can help unlock their potential applications.
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Chromatography VideoVideos

Scalable AAV Vector Purification Workflow Using AEX and Mixed-Mode Chromatography

Anion exchange and mixed-mode chromatography offer efficient and flexible AAV purification. Learn new strategies for optimizing viral vector purification.
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Chromatography VideoVideos

Efficient and Rapid Purification of E. coli–Expressed Toxin Recombinant Protein Fragments

Tetanus toxoid (TT) is a common carrier protein for conjugate vaccines, but its production is faced with significant challenges. Learn about a purification process that yields over 98% pure target protein in this video.
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Chromatography VideoVideos

Assessing Viral Clearance in Early-Phase Process Development

Viral clearance studies are part of a multifaceted approach to ensure biopharmaceutical product safety. To prevent costly changes to a manufacturing process, it is important to assess each operation unit for its efficiency early on during downstream process development. See how a design of experiments (DOE) approach was utilized in this case study to investigate the effect of buffer pH and conductivity on the removal of impurities by an anion exchange (AEX) mixed-mode chromatography resin.
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Past WebinarsWebinars

Purification of DNA Oligonucleotides using Anion Exchange Chromatography

In this webcast, see how Nuvia HP-Q Resin, an anion exchange resin, was used to purify oligonucleotides with phosphodiester backbones in a scaleable workflow.
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Nuvia HP-Q
ChromatographyPast WebinarsWebinars

Large Biomolecule Purification with a New High-Performance Anion Exchange Resin

Presented by: Hana Kim, PhD, Global Product Manager, Process Chromatography
Jiali Liao, PhD, Principal Scientist, Process Chromatography

View on demand

Learn about Nuvia HP-Q Resin, a new rigid bead engineered with large pores and optimized surface extenders to deliver both high binding capacity and high recovery at high flow rates. It is ideal for large molecule purification, including plasma proteins, viruses, and VLPs.

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A Resin for Purification of Large Biomolecules
ArticlesChromatographyProduct Highlights

A Resin Built Specifically for Large Biomolecule Purifications

Nuvia HP-Q is a high-performance strong anion exchange resin designed for purification of large biomolecules. See how its optimized particle and pore size leads to high target recovery and high-throughput purifications.
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