ArticlesDrug Discovery and DevelopmentTechniques

Saving Lives: Innovative Therapeutic Applications of Ion Exchange Resins

Although chromatography resins are usually thought of as tools to purify medicines, groundbreaking treatments now utilize resin beads as an integral component of the therapy itself. These therapies are essential for treating certain cancers and inflammatory disorders.
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ArticlesDrug Discovery and DevelopmentResearch Highlights

The Journey from Lab to Clinic: Zolgensma, the First Gene Therapy Treatment for Spinal Muscular Atrophy (SMA)

Translational research bridges the gap between scientific discoveries and real-world applications, transforming scientific breakthroughs into life-changing therapies. Success in this endeavor hinges on several factors, including collaboration between scientists and clinicians. A notable example of this is the approval of Zolgensma, a gene therapy for spinal muscular atrophy (SMA), which marked a significant milestone in the field of translational research.
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ArticlesCell BiologyDroplet Digital PCR (ddPCR)

Vive la Différence: The Beauty of Diversity in Life, Life Science, and Flow Cytometry

The differences between us are what makes life interesting, and diversity in a group that shares a common goal can lead to many benefits. Here we examine the similarities and differences between researchers using flow cytometry for academic research and those using it for drug discovery. We outline the challenges they face and learn that they share a common goal as well as a common solution.
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ArticlesElectrophoresis/Western Blotting

Compliance at Your Fingertips: Using Image Lab Touch Software for Digital Imaging in Regulated Environments

Maintaining compliance while leveraging advanced digital imaging technologies can be a daunting task. Luckily, Bio-Rad Image Lab Touch Software takes this challenge head-on by offering a seamless solution for digital imaging. Learn how Image Lab Touch Software integrates with Bio-Rad imaging systems to support researchers in meeting stringent regulatory requirements, ensuring data integrity and security without compromising efficiency or ease of use.
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Customer Testimonial VideoDroplet Digital PCR (ddPCR) VideoVideos

Global Lung Cancer Expert Dr. Ed Schuuring on How ddPCR Technology Powers ctDNA Analysis

Characterizing biomarkers in lung cancer tumors is challenging due to the high risks associated with tissue retrieval. Liquid biopsy offers a safer alternative but requires highly sensitive and precise methods to generate robust results from minimal genetic material. In this video, Dr. Schuuring of the University Medical Center Groningen discusses how Droplet Digital PCR (ddPCR) is used in his laboratories and why this technology has become critical for his research.
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Cell Biology VideoGeneral InterestGeneral Interest VideoVideos

Biotherapeutic Antibody Discovery at Bio-Rad’s New Center for Excellence

The Pioneer Platform features one of the largest functional antibody libraries available, utilizing SpyLock technology for rapid prototyping and screening of hundreds of bispecific antibodies, and TrailBlazer technology for efficient antibody format conversion. Together, these services provide a comprehensive and streamlined solution for researchers seeking to develop innovative biotherapeutic therapies.
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ArticlesReal-time qPCR/PCR

Maximizing PCR and qPCR Throughput with Automated Solutions

Automation in PCR and qPCR processes is revolutionizing laboratory workflows in regulated environments like biopharma and CROs. By enhancing efficiency, reducing manual errors, and ensuring compliance with regulatory standards, automation allows labs to scale operations and increase throughput without compromising data quality. Here we show the range of Bio-Rad products that are compatible with automated solutions for PCR and qPCR workflows.
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Chromatography VideoVideos

Development of an IEX Purification Process for Lentiviral Vectors

In recent years, gene therapy treatments have increased significantly, requiring more efficient processes to purify and deliver these therapeutics. Lentiviral vectors (LVVs) are a type of retrovirus and are an effective tool for gene delivery. In this webinar, data are shown for a high-throughput screening strategy that was employed for LVV purification, which provided high yield as well as acceptable host cell protein (HCP) clearance.
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ChromatographyFeatured WebinarsWebinars

Evaluation of a New Multimodal Anion Exchange Resin for Emerging Biotherapeutic Process Challenges

Nuvia wPrime 2A Resin has MMAEX functionality with a weak anion exchanger. See data showing improved mAb and bsAb purification compared to traditional resins.
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Cell BiologyFeatured WebinarsWebinars

Cytometry in Drug Discovery: An Introduction to Regulation, Standardization, and Productivity

Many researchers learn flow cytometry in academia, but find new challenges in the commercial sector. In this webinar, learn about regulatory issues and more.
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