Development of an IEX Purification Process for Lentiviral Vectors
In recent years, gene therapy treatments have increased significantly, requiring more efficient processes to purify and deliver these therapeutics. Lentiviral vectors (LVVs) are a type of retrovirus and are an effective tool for gene delivery. In this webinar, data are shown for a high-throughput screening strategy that was employed for LVV purification, which provided high yield as well as acceptable host cell protein (HCP) clearance.
Evaluation of a New Multimodal Anion Exchange Resin for Emerging Biotherapeutic Process Challenges
Nuvia wPrime 2A Resin has MMAEX functionality with a weak anion exchanger. See data showing improved mAb and bsAb purification compared to traditional resins.
Cytometry in Drug Discovery: An Introduction to Regulation, Standardization, and Productivity
Many researchers learn flow cytometry in academia, but find new challenges in the commercial sector. In this webinar, learn about regulatory issues and more.
Insights from Droplet Digital PCR World 2024
In June, Bio-Rad hosted Droplet Digital PCR (ddPCR) World 2024, the premier digital PCR event bringing together global leaders in science and innovation. ddPCR World features experts showcasing how ddPCR technology has been instrumental in overcoming some of their most complex research and manufacturing challenges. In this article, we are excited to share key insights and cutting-edge research using ddPCR technology that are driving scientific breakthroughs across the globe.
Coming Together Is the Beginning: Working Together Is the Success
Follow the story of Evitria as it grows from a small Chinese hamster ovary (CHO) cell supernatant supplier to a global therapeutic antibody production company serving clients across the globe. Bio-Rad has partnered with Evitria at every stage of this remarkable journey and looks forward to supporting its continued success.
Developing Efficient Downstream Purification Processes for Bispecific Antibodies
Modern chromatographic resins enable new strategies for downstream processing of bispecific antibodies. Watch this webinar to see case studies and workflows.
How to Harness Regulatory Compliance Capabilities with Image Lab Touch Software for Western Blotting and Gel Electrophoresis
Improve western blotting and gel electrophoresis data security with Image Lab Touch Software. See features that support regulatory compliance in this webinar.
Step into the Future of Blot and Gel Imaging with the ChemiDoc Go Imaging System
The ChemiDoc Go Imaging System, the newest in the ChemiDoc imaging line, effortlessly captures precise, high-sensitivity images of western blots and nucleic acid gels from a compact benchtop system — transforming lab workflows. Explore how this next-generation imager redefines your research capabilities across various applications, including multiplexing and stain-free protein detection.
Strategies to Address Large Molecule Purification Challenges
Large molecule purification presents significant challenges due to their considerable size. For instance, Immunoglobulin M (IgM) molecules, ranging from 900 to 1,000 kD, play pivotal roles in mammalian immune responses and find extensive applications in diagnostics and therapeutics. Purification of such molecules is particularly intricate owing to several factors including their weak Protein A binding sites, limited dynamic binding capacity, and slow diffusion rates.
Unlocking the Potential of Cell and Gene Therapies: Overcoming Production Challenges
A common challenge in scaling up cell and gene therapy production is monitoring for contaminants, such as Mycoplasma. Learn how ddPCR can help in this webinar.