Monoclonal Antibody Purification: A Two-Step Approach Using a Strong AEX-HIC Mixed-Mode Resin
Monoclonal antibodies (mAbs) increasingly comprise a large portion of the product pipeline of major biopharmaceutical companies. Challenges in mAb purification include reducing production cost, developing robust processes for both product purity and viral clearance, and integrating upstream …
A Gentler Workflow: Fc-Fusion Protein Purification with Mixed-Mode and Anion Exchange Chromatography
Traditional Protein A affinity chromatography is the gold standard for Fc-fusion protein purification, but protein denaturation and degradation due to low-pH elution are limitations. This webcast presents a proof-of-concept study demonstrating the use of …
Evaluation of A New Multimodal Anion Exchange Resin for Emerging Biotherapeutic Process Challenges
Multimodal chromatography has a history of providing value for biopharmaceutical separations. Ligands that enable binding based on both charge and hydrophobic interactions provide more opportunity for effective separation of multiple …
Optimize Your Assays for High-Throughput Flow Cytometry
Flow cytometry is a powerful technique with many applications in both academia and drug discovery. It can facilitate complex immunophenotyping experiments, making it an indispensable tool for understanding biological systems. …
BioRad.io Podcast Series
The BioRad.io podcast series is focused on R&D informatics, introducing you to people responsible for implementing systems and technologies to a diverse set of use-cases. Join us every month to see what you can learn.
Bio-Rad’s Downstream Process Development Support and Services
Bio-Rad’s Chromatography Support Scientist, Artur Stanczak, discusses the company’s comprehensive downstream process development services. From method development to troubleshooting, Bio-Rad provides specialized support to help customers overcome bioprocessing challenges. Access tools, case studies, and expert guidance to optimize processes and advance biomanufacturing efforts in this informative video.
Compliance and Regulations for Flow Cytometry in Drug Discovery: Webinar Series
In this webinar series, learn about 21 CFR Part 11 regulations for flow cytometry in drug discovery. Learn what software and instruments can help you comply.
Demonstrating a Modular Selectivity with a Weak AEX-HIC Resin for Achieving High mAb Purity and Recovery in a Downstream Process
Learn how Bio-Rad’s Nuvia wPrime 2A Media, a weak AEX-HIC resin, is used in an efficient monoclonal antibody (mAb) purification process. Presented by Dr. Sushmita Koley, this webcast demonstrates how multimodal chromatography improves purity and recovery, achieving a 10x reduction in high molecular weight species while maintaining 85% mAb monomer recovery. Watch to explore innovative solutions for biomanufacturing.
Global Lung Cancer Expert Dr. Ed Schuuring on How ddPCR Technology Powers ctDNA Analysis
Characterizing biomarkers in lung cancer tumors is challenging due to the high risks associated with tissue retrieval. Liquid biopsy offers a safer alternative but requires highly sensitive and precise methods to generate robust results from minimal genetic material. In this video, Dr. Schuuring of the University Medical Center Groningen discusses how Droplet Digital PCR (ddPCR) is used in his laboratories and why this technology has become critical for his research.
Biotherapeutic Antibody Discovery at Bio-Rad’s New Center for Excellence
The Pioneer Platform features one of the largest functional antibody libraries available, utilizing SpyLock technology for rapid prototyping and screening of hundreds of bispecific antibodies, and TrailBlazer technology for efficient antibody format conversion. Together, these services provide a comprehensive and streamlined solution for researchers seeking to develop innovative biotherapeutic therapies.