Videos | Bio-Radiations

Monoclonal Antibody Purification:  A Two-Step Approach Using a Strong AEX-HIC Mixed-Mode Resin

Bioradiations Staff — Fri, 30 Jan 2026 21:45:00 +0000

Monoclonal antibodies (mAbs) increasingly comprise a large portion of the product pipeline of major biopharmaceutical companies. Challenges in mAb purification include reducing production cost, developing robust processes for both product purity and viral clearance, and integrating upstream ...

The post Monoclonal Antibody Purification:  A Two-Step Approach Using a Strong AEX-HIC Mixed-Mode Resin first appeared on Bio-Radiations.

Evaluation of A New Multimodal Anion Exchange Resin for Emerging Biotherapeutic Process Challenges

Bioradiations Staff — Tue, 11 Nov 2025 17:54:04 +0000

Multimodal chromatography has a history of providing value for biopharmaceutical separations. Ligands that enable binding based on both charge and hydrophobic interactions provide more opportunity for effective separation of multiple ...

The post Evaluation of A New Multimodal Anion Exchange Resin for Emerging Biotherapeutic Process Challenges first appeared on Bio-Radiations.

Bio-Rad’s Downstream Process Development Support and Services

Bioradiations Staff — Tue, 13 May 2025 18:21:00 +0000

Bio-Rad’s Chromatography Support Scientist, Artur Stanczak, discusses the company’s comprehensive downstream process development services. From method development to troubleshooting, Bio-Rad provides specialized support to help customers overcome bioprocessing challenges. Access tools, case studies, and expert guidance to optimize processes and advance biomanufacturing efforts in this informative video.

The post Bio-Rad’s Downstream Process Development Support and Services first appeared on Bio-Radiations.

Global Lung Cancer Expert Dr. Ed Schuuring on How ddPCR Technology Powers ctDNA Analysis

Bioradiations Staff — Tue, 11 Feb 2025 18:43:53 +0000

Characterizing biomarkers in lung cancer tumors is challenging due to the high risks associated with tissue retrieval. Liquid biopsy offers a safer alternative but requires highly sensitive and precise methods to generate robust results from minimal genetic material. In this video, Dr. Schuuring of the University Medical Center Groningen discusses how Droplet Digital PCR (ddPCR) is used in his laboratories and why this technology has become critical for his research.

The post Global Lung Cancer Expert Dr. Ed Schuuring on How ddPCR Technology Powers ctDNA Analysis first appeared on Bio-Radiations.

Biotherapeutic Antibody Discovery at Bio-Rad’s New Center for Excellence

Bioradiations Staff — Tue, 11 Feb 2025 18:19:21 +0000

The Pioneer Platform features one of the largest functional antibody libraries available, utilizing SpyLock technology for rapid prototyping and screening of hundreds of bispecific antibodies, and TrailBlazer technology for efficient antibody format conversion. Together, these services provide a comprehensive and streamlined solution for researchers seeking to develop innovative biotherapeutic therapies.

The post Biotherapeutic Antibody Discovery at Bio-Rad’s New Center for Excellence first appeared on Bio-Radiations.

Development of an IEX Purification Process for Lentiviral Vectors

Bioradiations Staff — Tue, 11 Feb 2025 18:03:46 +0000

In recent years, gene therapy treatments have increased significantly, requiring more efficient processes to purify and deliver these therapeutics. Lentiviral vectors (LVVs) are a type of retrovirus and are an effective tool for gene delivery. In this webinar, data are shown for a high-throughput screening strategy that was employed for LVV purification, which provided high yield as well as acceptable host cell protein (HCP) clearance.

The post Development of an IEX Purification Process for Lentiviral Vectors first appeared on Bio-Radiations.

Coming Together Is the Beginning: Working Together Is the Success

Bioradiations Staff — Tue, 12 Nov 2024 17:35:27 +0000

Follow the story of Evitria as it grows from a small Chinese hamster ovary (CHO) cell supernatant supplier to a global therapeutic antibody production company serving clients across the globe. Bio-Rad has partnered with Evitria at every stage of this remarkable journey and looks forward to supporting its continued success.

The post Coming Together Is the Beginning: Working Together Is the Success first appeared on Bio-Radiations.

Step into the Future of Blot and Gel Imaging with the ChemiDoc Go Imaging System

Bioradiations Staff — Tue, 13 Aug 2024 20:57:01 +0000

The ChemiDoc Go Imaging System, the newest in the ChemiDoc imaging line, effortlessly captures precise, high-sensitivity images of western blots and nucleic acid gels from a compact benchtop system — transforming lab workflows. Explore how this next-generation imager redefines your research capabilities across various applications, including multiplexing and stain-free protein detection.

The post Step into the Future of Blot and Gel Imaging with the ChemiDoc Go Imaging System first appeared on Bio-Radiations.

Strategies to Address Large Molecule Purification Challenges

Bioradiations Staff — Tue, 13 Aug 2024 19:44:48 +0000

Large molecule purification presents significant challenges due to their considerable size. For instance, Immunoglobulin M (IgM) molecules, ranging from 900 to 1,000 kD, play pivotal roles in mammalian immune responses and find extensive applications in diagnostics and therapeutics. Purification of such molecules is particularly intricate owing to several factors including their weak Protein A binding sites, limited dynamic binding capacity, and slow diffusion rates.

The post Strategies to Address Large Molecule Purification Challenges first appeared on Bio-Radiations.

CHT Chromatography Media: 5 Essential Facts

Bioradiations Staff — Tue, 11 Jun 2024 18:47:14 +0000

For over 30 years, CHT Ceramic Hydroxyapatite Chromatography Media has been a trusted, proven purification solution for many biopharmaceutical manufacturing processes. CHT Media provides exceptional removal of impurities when other chromatography resins fall short.
In this webcast, explore the essential facts and benefits of this chromatography technology.

The post CHT Chromatography Media: 5 Essential Facts first appeared on Bio-Radiations.

PrimePCR Assays: Your Path to a Custom PCR Plate

Bioradiations Staff — Tue, 11 Jun 2024 18:41:24 +0000

Discover the simplicity of crafting your own custom PrimePCR plate with Bio-Rad. Follow along with our intuitive plate wizard, which helps you select your plate type (96- or 384-well) and compatible qPCR instrument for precise assay delivery. Watch this video to see how.

The post PrimePCR Assays: Your Path to a Custom PCR Plate first appeared on Bio-Radiations.

Scalable AAV Vector Purification Workflow Using AEX and Mixed-Mode Chromatography

Bioradiations Staff — Mon, 12 Feb 2024 18:12:35 +0000

Anion exchange and mixed-mode chromatography offer efficient and flexible AAV purification. Learn new strategies for optimizing viral vector purification.

The post Scalable AAV Vector Purification Workflow Using AEX and Mixed-Mode Chromatography first appeared on Bio-Radiations.

StarBright Dyes for Flow Cytometry

Bioradiations Staff — Mon, 12 Feb 2024 18:11:40 +0000

Watch this video to learn about the many benefits of StarBright Dyes — our proprietary fluorescent nanoparticles — and see how they can help you build bigger, better flow cytometry panels with ease. StarBright Dyes have been designed to be stable, with superior brightness, narrow excitation and emission characteristics, and the flexibility to be included in new and existing experiments. They offer improved resolution of specific cell populations and minimized spillover and spreading.

The post StarBright Dyes for Flow Cytometry first appeared on Bio-Radiations.

Did You Know That Beyond Sensitivity, ddPCR Provides Unrivaled Precision and Accuracy?

Bioradiations Staff — Tue, 14 Nov 2023 19:53:26 +0000

Methods that are highly accurate and precise provide the right answer, consistently. For digital PCR (dPCR), Poisson statistics dictate that the accuracy and precision of results are dependent on the accuracy and precision of sample partitions. This means that to get reliable dPCR results, you need to know your partition volume accurately and your partition volumes need to be consistent. See how our Droplet Digital PCR technology provides both accuracy and precision.

The post Did You Know That Beyond Sensitivity, ddPCR Provides Unrivaled Precision and Accuracy? first appeared on Bio-Radiations.

The Pioneer Antibody Discovery Platform: Clinical-Quality Lead Candidates in Industry-Leading Timelines

Bioradiations Staff — Tue, 14 Nov 2023 19:51:08 +0000

Biotherapeutic antibody discovery is inherently challenging. Amongst the clinically proven technologies for antibody discovery is phage display — a technique utilized by one of the most recent and innovative solutions on the market: the Pioneer Antibody Discovery Platform.

The post The Pioneer Antibody Discovery Platform: Clinical-Quality Lead Candidates in Industry-Leading Timelines first appeared on Bio-Radiations.

Explore the Epigenomic Landscape of Single Cells with the scATAC You Seq

Bioradiations Staff — Tue, 14 Nov 2023 19:39:16 +0000

Gain access to high-performance chromatin profiling to unravel the complexities of cellular heterogeneity, differentiation, and disease-specific alterations in gene regulation. With single-cell ATAC-seq (assay for transposase-accessible chromatin using sequencing), you can delve into the gene regulatory landscape of individual cells, unlocking invaluable insights into the epigenomic mechanisms that shape their behavior.

The post Explore the Epigenomic Landscape of Single Cells with the scATAC You Seq first appeared on Bio-Radiations.

mAb Purification Process Development Using Mixed-Mode Resins — The DOE Approach

Bioradiations Staff — Tue, 14 Nov 2023 19:36:16 +0000

In this case study, process chromatography application scientist Artur Stanczak presents a two-step mAb purification workflow, comparing multimodal resin alternatives used for the polishing step that occurs after protein A capture. The design of experiment (DOE) data presented characterizes the behavior of multiple mAbs with two different mixed-mode resins. The importance of scale, prior knowledge, and the stage of development will also be discussed. The results of both mixed-mode resin studies and the different DOE approaches demonstrate the ability to achieve high-purity products.

The post mAb Purification Process Development Using Mixed-Mode Resins — The DOE Approach first appeared on Bio-Radiations.

Introducing the PTC Tempo Thermal Cycler

Bioradiations Staff — Mon, 07 Aug 2023 21:04:11 +0000

The PTC Tempo Thermal Cycler represents the next generation of conventional PCR thermal cyclers from Bio-Rad. Engineered to maintain thermal performance, the PTC Tempo Thermal Cycler offers the flexibility to scale with your laboratory. The design features a refreshed, intuitive user interface and flexible connectivity options for streamlining protocol management. A motorized lid enables automation, taking your PCR to the next level with modern instrument control.

The post Introducing the PTC Tempo Thermal Cycler first appeared on Bio-Radiations.

Efficient and Rapid Purification of E. coli–Expressed Toxin Recombinant Protein Fragments

Bioradiations Staff — Mon, 07 Aug 2023 20:22:55 +0000

Tetanus toxoid (TT) is a common carrier protein for conjugate vaccines, but its production is faced with significant challenges. Learn about a purification process that yields over 98% pure target protein in this video.

The post Efficient and Rapid Purification of E. coli–Expressed Toxin Recombinant Protein Fragments first appeared on Bio-Radiations.

Assessing Viral Clearance in Early-Phase Process Development

Bioradiations Staff — Wed, 10 May 2023 07:59:07 +0000

Viral clearance studies are part of a multifaceted approach to ensure biopharmaceutical product safety. To prevent costly changes to a manufacturing process, it is important to assess each operation unit for its efficiency early on during downstream process development. See how a design of experiments (DOE) approach was utilized in this case study to investigate the effect of buffer pH and conductivity on the removal of impurities by an anion exchange (AEX) mixed-mode chromatography resin.

The post Assessing Viral Clearance in Early-Phase Process Development first appeared on Bio-Radiations.

Scalable Purification Strategies for Viral Vectors and Vaccines

Bioradiations Staff — Tue, 14 Feb 2023 21:05:00 +0000

Large-scale downstream processing of viruses can face a range of obstacles different from those of many biotherapeutics. These challenges mostly arise from the size and complexity of the virus, which can affect product purity and recovery. Improvements of purification tools are necessary to overcome these challenges and must be engineered for easy scalability to meet manufacturing demands. In this video, Dr. Mark Snyder discusses common difficulties when developing purification strategies for vaccine production and gene therapy.

The post Scalable Purification Strategies for Viral Vectors and Vaccines first appeared on Bio-Radiations.

Quick Tips for Western Blotting

Bioradiations Staff — Tue, 14 Feb 2023 19:30:23 +0000

Learn how to improve your western blotting results with our Quick Tips video series. Watch these 1–2 minute videos see how to perfect each step of the western blotting process.

The post Quick Tips for Western Blotting first appeared on Bio-Radiations.

What You Need to Know About Packing Resins at Process Scale

Bioradiations Staff — Tue, 11 Oct 2022 18:33:11 +0000

Learn best practices and guidelines for successfully packing different types of chromatography resins in this video webinar. This includes incompressible resins, like CHT Ceramic Hydroxyapatite Media, as well as traditional compressible resins. In general, parameters such as compression factor, settling rate, and attributes of the base matrix need to be considered when packing resins at process scale. Packing methods can be adapted to obtain simple, highly reproducible packing. Get tips here.

The post What You Need to Know About Packing Resins at Process Scale first appeared on Bio-Radiations.

Quick Tips for Bio-Plex Assays

Bioradiations Staff — Tue, 11 Oct 2022 18:25:03 +0000

It is imperative to plan and prepare ahead of time for your research using Bio-Plex Assays to be successful. Good assay planning and preparation reduces mistakes and makes for a stress-free assay run. In this series of short videos, we share some simple steps you can take to make sure your work goes smoothly.

The post Quick Tips for Bio-Plex Assays first appeared on Bio-Radiations.

The CFX Duet Real-Time PCR System: Our Most Accessible qPCR Technology

Bioradiations Staff — Wed, 13 Jul 2022 02:43:34 +0000

Through the CFX Duet Real-Time PCR System, our newest generation of quantitative PCR (qPCR) instrumentation, this technology is now even more accessible for molecular biologists and other professionals doing essential qPCR. With CFX Maestro Software, you can perform duplex detection, gene expression, and genotyping, all without paying for additional optics you don’t need. Check out our video tour of the new CFX Duet System.

The post The CFX Duet Real-Time PCR System: Our Most Accessible qPCR Technology first appeared on Bio-Radiations.

Take the Expressway to RNA Library Prep

Bioradiations Staff — Wed, 13 Jul 2022 02:18:43 +0000

RNA-Seq library preparation is a manually intensive, time-consuming process prone to bias from the multiple enzymes required. So, how can you trust your sequencing results? Bio-Rad is revolutionizing RNA-Seq library prep with the SEQuoia Express Stranded RNA Library Prep Kit – a three-hour, three-tube solution eliminating the need for multiple enzymes and reducing both the number of pipetting steps and protocol time. The key is an engineered, proprietary retrotransposon called SEQzyme. With this serial template jumping, or continuous synthesis, reaction you can obtain an unbiased, stranded RNA-Seq library constructed to accurately represent both messenger and non-coding RNA from your sample.

The post Take the Expressway to RNA Library Prep first appeared on Bio-Radiations.

Multiplex SARS-CoV-2 Variant Neutralization Antibody Assays: Get Multiple Variant Results Fast

Bioradiations Staff — Wed, 13 Jul 2022 02:10:38 +0000

Bio-Plex Pro SARS-CoV-2 Neutralization Antibody Assays provide reliably measure neutralizing antibodies in less than 3 hours. Watch our webinar to learn more.

The post Multiplex SARS-CoV-2 Variant Neutralization Antibody Assays: Get Multiple Variant Results Fast first appeared on Bio-Radiations.

A Mixed-Mode Approach — An Alternative to a Three-Step mAb Purification Process

Bioradiations Staff — Wed, 13 Jul 2022 01:41:32 +0000

Monoclonal antibody (mAb) purification methods often involve the use of resin-based chromatography. In this video, we compare a three-step mAb purification workflow, which uses Nuvia Ion Exchange Resins post–Protein A capture, to a two-step purification workflow, which includes a Protein A capture step followed by a mixed-mode chromatography step using Nuvia aPrime 4A Resin, a hydrophobic anion exchange resin. We present an additional two-step purification approach using Protein A resin followed by a calcium affinity cation exchange media, CHT Ceramic Hydroxyapatite XT Media. The results of both studies demonstrate that a high purity product can be attained using one fewer unit operation than traditional workflows.

The post A Mixed-Mode Approach — An Alternative to a Three-Step mAb Purification Process first appeared on Bio-Radiations.

The PI3K-AKT Pathway and Its Role in Tumorigenesis

Bioradiations Staff — Tue, 12 Apr 2022 16:21:43 +0000

The phosphoinositide 3-kinase/protein kinase B (PI3K-AKT) pathway is involved in the control of numerous critical cellular processes. PI3K-AKT pathway dysfunction has been observed in several diseases, including cancer, cardiovascular disease, and autoimmune and neurological disorders. In this animation, learn more about the molecular characteristics and function of the PI3K-AKT pathway and how AKT mutation plays a role in tumorigenesis.

The post The PI3K-AKT Pathway and Its Role in Tumorigenesis first appeared on Bio-Radiations.

Manufacturing a Recombinant Retrovirus — Downstream Purification Process Development

Bioradiations Staff — Tue, 12 Apr 2022 16:19:30 +0000

Enveloped virus and VLP purification can be difficult. Learn about key factors and a cGMP-compatible, low cost, scalable process for retrovirus vector capture.

The post Manufacturing a Recombinant Retrovirus — Downstream Purification Process Development first appeared on Bio-Radiations.

The ZE5 Cell Analyzer, a Fast and Flexible Flow Cytometer for High-Throughput Screening

Bioradiations Staff — Tue, 12 Apr 2022 16:18:41 +0000

High-throughput screening (HTS) is a critical component of the entire drug discovery process. Flow cytometry is an attractive alternative to imaging and plate reader assays for HTS in drug discovery, due to its increased sensitivity and multiplexing capabilities. The ZE5 Cell Analyzer eliminates pain points that have hindered the full adoption of flow cytometry for drug discovery.

The post The ZE5 Cell Analyzer, a Fast and Flexible Flow Cytometer for High-Throughput Screening first appeared on Bio-Radiations.

A Novel Technology for Post-Library rRNA Depletion

Bioradiations Staff — Tue, 11 Jan 2022 08:39:46 +0000

The SEQuoia RiboDepletion Kit employs novel technology to deplete ribosomal RNA while preserving rare transcripts and small RNAs, as well as minimizing the risk of degrading or low abundant samples. The SEQuoia RiboDepletion Kit also offers a streamlined workflow and multiplex compatibility, leading to significant time and cost savings compared to traditional methods. Watch this video to learn more.

The post A Novel Technology for Post-Library rRNA Depletion first appeared on Bio-Radiations.

Choosing Validated Antibodies for Trustworthy Data

Bioradiations Staff — Tue, 11 Jan 2022 08:39:11 +0000

The lack of reproducibility in research has been a source of frustration for scientists. Learn why antibody validation is critical for ensuring specificity and what validation methods Bio-Rad is implementing. Our scientists validate the performance of antibodies through CRISPR-Cas9 gene editing by knockout (KO), siRNA knockdown (KD), and immunoprecipitation followed by mass spectrometry (IP-MS).

The post Choosing Validated Antibodies for Trustworthy Data first appeared on Bio-Radiations.

A Scalable Immobilized Metal Affinity Chromatography Media for Process Purification

Bioradiations Staff — Tue, 11 Jan 2022 08:38:19 +0000

Downstream process purification of proteins requires a resin with optimized bead size for ideal pressure/flow properties and decent dynamic binding capacity (DBC) that provides production efficiencies and good process economics. Nuvia IMAC Resin provides the mechanical strength, pore structures, ligand density, and particle size distribution required for an operational run at 300 cm/hr with a DBC of 40 mg/ml at 2 bar column backpressure. Protein purification can efficiently be scaled up from milligrams in the lab to kilograms in bioprocess manufacturing. The chemical stability of Nuvia IMAC Resins ensure efficient column regeneration, reproducibility between purification runs, extended column lifetime, and product purity. Watch our video to learn how Nuvia IMAC Resins overcome the challenges associated with process purification of proteins using metal affinity chromatography.

The post A Scalable Immobilized Metal Affinity Chromatography Media for Process Purification first appeared on Bio-Radiations.

Two-Step Purification of Low-Expressing Recombinant Exoprotein A Using Mixed-Mode Chromatography

Bioradiations Staff — Tue, 14 Sep 2021 16:32:01 +0000

Purifying proteins that are not highly expressed can be challenging. Watch this video to learn about a case study demonstrating an efficient workflow for two-step purification of a low-expressing recombinant protein using mixed-mode chromatography.

The post Two-Step Purification of Low-Expressing Recombinant Exoprotein A Using Mixed-Mode Chromatography first appeared on Bio-Radiations.

Single-Step Column Purification for H1N1 VirusUsing Nuvia HP-Q AEX Resin

Bioradiations Staff — Wed, 09 Jun 2021 00:01:27 +0000

Learn how a team developed a single-step workflow for column purification of the Influenza A H1N1 subtype using the recently developed Nuvia HP-Q Anion Exchange Resin. This protocol is scalable, efficient, and produced good yields with high purity.

The post Single-Step Column Purification for H1N1 Virus
Using Nuvia HP-Q AEX Resin first appeared on Bio-Radiations.

Advantages of Multiplexing with Bio-Plex Assays

Bioradiations Staff — Tue, 08 Jun 2021 23:53:19 +0000

The Bio-Plex Assay development process is designed to produce high performance multiplex assays. We prioritize sensitivity, broad dynamic range, reproducibility, and shorter incubation times to get you meaningful results faster. Watch this video to learn more about our SMARTS approach to assay development.

The post Advantages of Multiplexing with Bio-Plex Assays first appeared on Bio-Radiations.

Maximizing the Efficiency of Production Workflows with NGC Chromatography Systems

Bioradiations Staff — Thu, 12 Dec 2019 00:00:51 +0000

See how an antibody expression service provider, Evitria (Zurich, Switzerland) optimized and expanded their antibody production services using the NGC Chromatography Systems to meet the growing demands of their customers.

The post Maximizing the Efficiency of Production Workflows with NGC Chromatography Systems first appeared on Bio-Radiations.

Discover lncRNA: Understanding the Long Noncoding Transcriptome

Bioradiations Staff — Wed, 14 Nov 2018 20:04:35 +0000

Learn about the exciting new field of long noncoding RNA (lncRNA) and how this newly discovered class of RNA compares to messenger RNA (mRNA).

The post Discover lncRNA: Understanding the Long Noncoding Transcriptome first appeared on Bio-Radiations.

Identifying Predictive Biomarkers for Successful Immunotherapy Treatments

Bioradiations Staff — Tue, 09 Jan 2018 23:08:16 +0000

Find out how the S3e™ Cell Sorter can help scientists discover new biomarkers that have the potential to become new therapies for cancer and other diseases.

The post Identifying Predictive Biomarkers for Successful Immunotherapy Treatments first appeared on Bio-Radiations.

Get More Answers from Your Mouse with the Bio-Plex Pro™ Mouse Chemokine Panel

Bioradiations Staff — Thu, 15 Jun 2017 20:59:30 +0000

Biomarker screening can sometimes be like working in a black box. While traditional research tools focus on one protein at a time, Bio-Rad’s new Bio-Plex Pro™ Mouse Chemokine Panel can simultaneously interrogate 33 chemokines and cytokines in a single well. See how you can get more answers with this panel.

The post Get More Answers from Your Mouse with the Bio-Plex Pro™ Mouse Chemokine Panel first appeared on Bio-Radiations.

TGX Stain-Free™ FastCast™ Acrylamide Gel Casting

Bioradiations Staff — Thu, 10 Nov 2016 00:35:30 +0000

This short video demonstrates how you can access the unique benefits of Bio-Rad's proprietary TGX Stain-Free Gel chemistry by hand casting your own TGX Stain-Free Gels in just a few quick and easy steps.

The post TGX Stain-Free™ FastCast™ Acrylamide Gel Casting first appeared on Bio-Radiations.

Introduction to Algae Beads, Photosynthesis, and Cellular Respiration

Bioradiations Staff — Thu, 10 Nov 2016 00:22:26 +0000

Introduce students (and teachers) to the concepts of photosynthesis and cellular respiration in the context of how these processes evolved and how they affect our daily lives.

The post Introduction to Algae Beads, Photosynthesis, and Cellular Respiration first appeared on Bio-Radiations.

Meet the Brightest ECL Substrate Around — Clarity Max™ Western ECL Substrate

Bioradiations Staff — Thu, 13 Oct 2016 17:38:47 +0000

See how our new high-sensitivity western ECL substrate, Clarity Max, can help you achieve greater western blotting success.

The post Meet the Brightest ECL Substrate Around — Clarity Max™ Western ECL Substrate first appeared on Bio-Radiations.

Coupling Automated Chromatography with Faster Confirmation of Purity and Yield

Bioradiations Staff — Thu, 13 Oct 2016 17:36:47 +0000

We’ve combined the chromatography process with purity and yield assessment using stain-free gels to shorten and optimize your protein purification workflow. See how it’s done.

The post Coupling Automated Chromatography with Faster Confirmation of Purity and Yield first appeared on Bio-Radiations.

Cleaning the Nozzle Tip on the S3e™ Cell Sorter

Bioradiations Staff — Thu, 15 Sep 2016 23:20:54 +0000

In this short video, we show how to clean the nozzle tip on the S3e Cell Sorter.

The post Cleaning the Nozzle Tip on the S3e™ Cell Sorter first appeared on Bio-Radiations.

Performing a Fluidics Hot Swap on the S3e™ Cell Sorter

Bioradiations Staff — Thu, 15 Sep 2016 23:13:47 +0000

In this video, we show how a fluidics hot swap can be performed without shutting down the S3e Cell Sorter.

The post Performing a Fluidics Hot Swap on the S3e™ Cell Sorter first appeared on Bio-Radiations.

Cleaning the Streams Camera Window on the S3e™ Cell Sorter

Bioradiations Staff — Thu, 15 Sep 2016 23:10:43 +0000

In this video we show you how to clean the camera streams window as part of routine maintenance for your S3e Cell Sorter.

The post Cleaning the Streams Camera Window on the S3e™ Cell Sorter first appeared on Bio-Radiations.

Attaching a Dynaloop to the NGC™ Chromatography System

Bioradiations Staff — Fri, 12 Aug 2016 04:47:07 +0000

This video describes the three main steps in attaching a DynaLoop Sample Loop to the NGC™ Chromatography System to enable the injection of larger sample volumes: connecting the DynaLoop Sample Loop to the NGC Chromatography System, priming the DynaLoop Sample Loop, and creating a method in ChromLab™ Software.

The post Attaching a Dynaloop to the NGC™ Chromatography System first appeared on Bio-Radiations.

Calibrating the pH Valve on the NGC™ Chromatography System

Bioradiations Staff — Fri, 12 Aug 2016 04:44:47 +0000

The NGC pH valve provides real-time, in-line monitoring of buffer pH. In this video, you’ll learn how to connect the pH valve to the NGC System, add it to the flow path, and calibrate the valve using buffers at two different pH values. Features of the pH valve include accessible calibration ports and easy bypass of the probe when the NGC System is being cleaned.

The post Calibrating the pH Valve on the NGC™ Chromatography System first appeared on Bio-Radiations.

Removing Air Bubbles from the NGC™ Chromatography System

Bioradiations Staff — Fri, 15 Jul 2016 21:21:39 +0000

This video explains how to remove bubbles and/or reduce bubble formation in your NGC System. Tips to reduce bubbles include warming up your multiwave detector for 30 to 60 min before use and flowing buffer at 0.1–0.2 ml/min in the manual mode until a stable/flat baseline is achieved before starting a method. The system may also be flushed with 100% methanol or ethanol at purge speed, with columns out of line, to remove bubbles.

The post Removing Air Bubbles from the NGC™ Chromatography System first appeared on Bio-Radiations.

Using the Air Sensor on the NGC™ Chromatography System

Bioradiations Staff — Fri, 15 Jul 2016 21:09:24 +0000

This video describes the functions of the Air Sensor Module and how to connect it to the NGC Chromatography System. The NGC Air Sensor senses the end of sample or buffer and prevents the introduction of air into the system, which can damage columns and/or incur the loss of precious samples. Both small and large air sensors are available to fit the tubing being used. Steps for connecting the Air Sensor Module and associated air sensors are described including how to add the air sensors into the system flow path using ChromLab™ Software and the differences in using the air sensors in manual vs. method modes.

The post Using the Air Sensor on the NGC™ Chromatography System first appeared on Bio-Radiations.

Research Review: Phasing Genomes using Droplet Digital™ PCR

Bioradiations Staff — Thu, 16 Jun 2016 22:05:29 +0000

Find out how a new Droplet Digital PCR-based technique called Drop Phase lets you quickly and easily phase genomes to better understand diseases like cystic fibrosis.

The post Research Review: Phasing Genomes using
Droplet Digital™ PCR first appeared on Bio-Radiations.

How Do You Automate a Multicolumn Protein Purification?

Bioradiations Staff — Wed, 11 May 2016 20:37:44 +0000

Multicolumn purifications are tedious and the manual operations during this process introduce variabilities, affecting the success of purification and reproducibility of results. This whiteboard animation explains how an automated multi-dimensional chromatography method can make this an easier process with very high success rates.

The post How Do You Automate a Multicolumn Protein Purification? first appeared on Bio-Radiations.

Expanding Flow Core Capabilities with the S3e™ Cell Sorter

Bioradiations Staff — Wed, 13 Apr 2016 01:00:38 +0000

Andy Riddell, Flow Cytometry Core Facility Manager at the Wellcome Trust- MRC Stem Cell Institutes, is expanding his core facility by allowing his researchers to conduct sorting on their own. In doing so, he is now free to explore and answer the challenging flow cytometry questions that require more of his expert time. Find out how the S3e Cell Sorter has allowed Andy that freedom and how easy sorting can be for researchers.

The post Expanding Flow Core Capabilities with the S3e™ Cell Sorter first appeared on Bio-Radiations.

Using PrimePCR™ qPCR Assays to Understand Breast Cancer Metastasis

Bioradiations Staff — Tue, 08 Mar 2016 08:00:43 +0000

Traci Lyons describes how PrimePCR Assays ended her laboratory’s struggle to find a qPCR assay that could reliably detect transcription of the cyclooxygenase-2 (Cox-2) gene, which they had identified as potentially prometastatic. Using the PrimePCR Assay for Cox-2, researchers in her lab were finally able to verify cyclooxygenase-2 knockdown, which is a necessary step toward confirming its role in breast cancer metastasis.

The post Using PrimePCR™ qPCR Assays to Understand Breast Cancer Metastasis first appeared on Bio-Radiations.

How Does the Mixed Mode Interaction of a Media Help Achieve High Selectivity and Resolution?

Bioradiations Staff — Tue, 09 Feb 2016 21:53:01 +0000

The best chromatography media should yield high protein purity and product recovery as well as be versatile enough to purify difficult samples. Bio-Rad’s CHT™ Ceramic Hydroxyapatite achieves this by virtue of being able to interact with the proteins through multiple modes, making the process extremely efficient. The whiteboard animation describes the mode of action of CHT.

The post How Does the Mixed Mode Interaction of a Media Help Achieve High Selectivity and Resolution? first appeared on Bio-Radiations.

Western Blotting without Trial and Error: Use PrecisionAb™ Antibodies

Bioradiations Staff — Tue, 09 Feb 2016 21:47:40 +0000

Watch this video to see how PrecisionAb Validated Western Blotting Antibodies are defining a new standard of quality that you can trust to deliver superior results and reproducibility in western blotting.

The post Western Blotting without Trial and Error: Use PrecisionAb™ Antibodies first appeared on Bio-Radiations.

How to Design Hydrolysis Probes for qPCR

Bioradiations Staff — Wed, 13 Jan 2016 01:52:26 +0000

What's the optimal melting temperature for a hydrolysis probe? How long should your probe be? And why should you avoid 5' guanines like the plague? This episode answers these questions and gives you five simple tricks for designing the perfect hydrolysis probe.

The post How to Design Hydrolysis Probes for qPCR first appeared on Bio-Radiations.

Six Tips for Increasing the Reproducibility of qPCR Experiments

Bioradiations Staff — Tue, 08 Dec 2015 19:02:53 +0000

Follow these six simple tips and you'll increase the reproducibility of your qPCR experiments.

The post Six Tips for Increasing the Reproducibility of qPCR Experiments first appeared on Bio-Radiations.

High-Processivity Sso7d Fusion Polymerase Improves qPCR Results

Bioradiations Staff — Tue, 08 Dec 2015 19:01:56 +0000

Processivity is the rate at which nucleotides are added to extend PCR products. High processivity results in a greater number of nucleotides incorporated in each polymerase binding event.

The post High-Processivity Sso7d Fusion Polymerase Improves qPCR Results first appeared on Bio-Radiations.

How to Minimize Contamination in qPCR Experiments

Bioradiations Staff — Tue, 10 Nov 2015 22:16:42 +0000

Are you using ethanol to prep your bench for qPCR? Watch this episode to find out why that might be a bad idea. We're sharing seven tips for minimizing contamination of qPCR experiments.

The post How to Minimize Contamination in qPCR Experiments first appeared on Bio-Radiations.

How to Design Primers for qPCR

Bioradiations Staff — Wed, 14 Oct 2015 00:33:11 +0000

How long should a qPCR primer be and what types of sequences should you avoid? In this episode we share eight tips and tricks for primer design for your qPCR experiments.

The post How to Design Primers for qPCR first appeared on Bio-Radiations.

Four Tips for Developing a Sample Prep Protocol for SDS-PAGE or Chromatography

Bioradiations Staff — Fri, 04 Sep 2015 17:53:25 +0000

From making sure that your lysis buffer is compatible with your protein quantitation method to advice on when you do and don't have to worry about proteases, we share helpful tips for developing a sample preparation protocol.

The post Four Tips for Developing a Sample Prep Protocol for SDS-PAGE or Chromatography first appeared on Bio-Radiations.

Five Tips for Picking the Right Cell Disruption Method for Protein Analysis

Bioradiations Staff — Fri, 04 Sep 2015 17:51:15 +0000

Sonicator or freeze-thaw? Detergent or enzymatic lysis? Find out how to pick the right cell disruption method for your experiment.

The post Five Tips for Picking the Right Cell Disruption Method for Protein Analysis first appeared on Bio-Radiations.

Four Tips for Handcasting SDS-PAGE Gels

Bioradiations Staff — Tue, 11 Aug 2015 22:30:00 +0000

Watch this episode of LabNotes for helpful tips like how to pour the stacking and resolving gel at the same time.

The post Four Tips for Handcasting SDS-PAGE Gels first appeared on Bio-Radiations.

Four Tips for Running the Perfect SDS-PAGE Gel

Bioradiations Staff — Tue, 11 Aug 2015 22:25:07 +0000

We share five simple tricks that address common gel running woes, from samples that float out of wells to sample buffers that turn yellow.

The post Four Tips for Running the Perfect SDS-PAGE Gel first appeared on Bio-Radiations.

Choosing the Right Percentage Gel

Bioradiations Staff — Wed, 15 Jul 2015 00:02:07 +0000

Unsure about what percentage SDS-PAGE gel to pick for your experiment? We share four tips that make picking the perfect gel a piece of cake.

The post Choosing the Right Percentage Gel first appeared on Bio-Radiations.

Automated Multi-D Chromatography on the NGC™ System

Bioradiations Staff — Wed, 15 Jul 2015 00:01:04 +0000

What is Multidimensional (Multi-D) chromatography? Here is an animated explanation of how Multi-D chromatography works and what its advantages are over traditional chromatography.

The post Automated Multi-D Chromatography on the NGC™ System first appeared on Bio-Radiations.

Minimizing Protein Degradation

Bioradiations Staff — Tue, 14 Jul 2015 21:12:41 +0000

In this episode, we share tips and tricks for minimizing protein degradation during cell lysis and sample preparation.

The post Minimizing Protein Degradation first appeared on Bio-Radiations.

High Quality Gene Expression from Precious Samples — A Simplified Workflow

Bioradiations Staff — Thu, 11 Jun 2015 17:45:48 +0000

Obtaining enough starting material to complete multiple gene expression experiments can be challenging when working with precious and limited samples. Find out how Mark Kibschull of the Lunenfeld-Tanenbaum Research Institute in Toronto determines pluripotency and differentiation of limited human embryonic stem cells using Bio-Rad's SingleShot Cell Lysis Kit, PreAmp Supermix, and PrimePCR validated primer panels. This simplified workflow allows for the gene expression analysis of hundreds of genes from as little as 100 human embryonic stem cells, and without the cumbersome step of isolating and purifying RNA.

The post High Quality Gene Expression from Precious Samples
— A Simplified Workflow first appeared on Bio-Radiations.

Teaching Inquiry in the Classroom

Bioradiations Staff — Wed, 20 May 2015 23:14:42 +0000

A look inside Julianne Zedalis' classroom at The Bishop's School in San Diego, CA, gives a glimpse of how a master teacher implements inquiry in her classroom. Bio-Rad's ThINQ! Investigations enable instructors to guide students through real-world inquiry investigations. These labs meet the revised College Board curriculum requirements and are aligned to AP Biology Big Ideas; they are designed to connect inquiry to NGSS and college curricula, encouraging students to think like real scientists.

The post Teaching Inquiry in the Classroom first appeared on Bio-Radiations.

Cell Imaging Simplified – the ZOE™ Fluorescent Cell Imager

Bioradiations Staff — Wed, 20 May 2015 22:41:58 +0000

The ZOE fluorescent cell imager features an integrated digital camera and touch-screen interface that makes brightfield and multichannel fluorescence microscopy simple, fast, and intuitive. An easy-to-use alternative to the traditional inverted microscope, ZOE eliminates the complexities of multichannel fluorescence imaging by combining the ease of use of a personal tablet and the power of an inverted microscope.

The post Cell Imaging Simplified – the ZOE™ Fluorescent Cell Imager first appeared on Bio-Radiations.

Tips for Keeping Your NGC™ Chromatography System in Great Shape

Bioradiations Staff — Wed, 11 Feb 2015 00:19:06 +0000

Doing these three simple checks will protect your chromatography system from common lab hazards.

The post Tips for Keeping Your NGC™ Chromatography System in Great Shape first appeared on Bio-Radiations.

Tips for Using Chromatography Columns with Your NGC™ Chromatography System

Bioradiations Staff — Wed, 11 Feb 2015 00:14:47 +0000

Here are the methods you need to ensure optimal, long-lasting column performance.

The post Tips for Using Chromatography Columns with Your NGC™ Chromatography System first appeared on Bio-Radiations.

Tips for Sample Preparation with Your NGC™ Chromatography System

Bioradiations Staff — Wed, 11 Feb 2015 00:09:47 +0000

Follow these steps to go from crude cell lysate to a sample that’s ready to purify.

The post Tips for Sample Preparation with Your NGC™ Chromatography System first appeared on Bio-Radiations.

Tips for Storing Proteins Purified on Your NGC™ Chromatography System

Bioradiations Staff — Wed, 11 Feb 2015 00:03:22 +0000

Get the most out of your proteins, including better stability, the best ways to freeze fractions, and more!

The post Tips for Storing Proteins Purified on Your NGC™ Chromatography System first appeared on Bio-Radiations.

Tips for Preparing and Using Buffers with Your NGC™ Chromatography System

Bioradiations Staff — Tue, 10 Feb 2015 19:28:57 +0000

Here are four fast and easy things that will help you maintain peak performance for your medium pressure chromatography system. Beat contamination and save your samples!

The post Tips for Preparing and Using Buffers with Your NGC™ Chromatography System first appeared on Bio-Radiations.

PureBlu™ Hoechst 33342 Nuclear Staining Dye for Live Cells – A Fast Approach to Staining Nuclei

Bioradiations Staff — Mon, 12 Jan 2015 20:00:47 +0000

PureBlu Hoechst 33342 Nuclear Staining Dye is the optimal choice for staining the nuclei of live cells for ultraviolet imaging. This short video goes through the steps involved in staining live cells with PureBlu Hoechst 33342 Nuclear Staining Dye.

The post PureBlu™ Hoechst 33342 Nuclear Staining Dye for Live Cells – A Fast Approach to Staining Nuclei first appeared on Bio-Radiations.

PrimePCR™ Pathway and Disease Panels – How to Modify a Predesigned Plate

Bioradiations Staff — Mon, 12 Jan 2015 20:00:45 +0000

One easy way to obtain a PrimePCR plate customized for your research is to modify one of Bio-Rad’s predesigned panels. This short video tutorial shows you how to use the online tools at Bio-Rad.com to edit a predesigned plate and create, then order your own customized 96- or 384-well PCR plate.

The post PrimePCR™ Pathway and Disease Panels – How to Modify a Predesigned Plate first appeared on Bio-Radiations.

How to Build a Custom PrimePCR™ Real-Time PCR Plate Using a Suggested or Blank Template

Bioradiations Staff — Mon, 12 Jan 2015 20:00:45 +0000

It’s fast and easy to build your own PrimePCR plate. This video walks you through using the Custom Plate Configurator at Bio-Rad.com to create your own 96- or 384-well PCR plate.

The post How to Build a Custom PrimePCR™ Real-Time PCR Plate Using a Suggested or Blank Template first appeared on Bio-Radiations.

PureBlu™ DAPI Nuclear Staining Dye for Fixed Cells – A Fast Approach to Staining Nuclei

Bioradiations Staff — Mon, 12 Jan 2015 20:00:43 +0000

PureBlu DAPI Nuclear Staining Dye is the optimal choice for staining the nuclei of fixed cells for ultraviolet imaging. This short video goes through the steps involved in staining live cells with PureBlu DAPI Nuclear Staining Dye.

The post PureBlu™ DAPI Nuclear Staining Dye for Fixed Cells – A Fast Approach to Staining Nuclei first appeared on Bio-Radiations.

Investigating Cancer Stem Cells with the S3™ Cell Sorter

Bioradiations Staff — Tue, 09 Dec 2014 20:00:56 +0000

At SUNY Downstate Medical Center in Brooklyn, New York, researchers Stacy Blain and Danielle Joseph are trying to find out how the Cancer Stem Cell model might apply to multiple myeloma. See how they use Bio-Rad’s S3 Cell Sorter to isolate a small population of cells that might play an important role in this disease.

The post Investigating Cancer Stem Cells with the S3™ Cell Sorter first appeared on Bio-Radiations.

How to Order PrimePCR™ Assays – Primers, Probes, and Panels

Bioradiations Staff — Tue, 09 Dec 2014 20:00:48 +0000

A wide range of PCR assays is available through Bio-Rad.com for use with real-time or Droplet Digital™ PCR systems. Get a quick refresher on ordering these products with this short video.

The post How to Order PrimePCR™ Assays – Primers, Probes, and Panels first appeared on Bio-Radiations.

You Get to Do This? – The Bio-Rad Science Ambassador Program at the 2014 Bay Area Science Festival

Bioradiations Staff — Tue, 09 Dec 2014 20:00:46 +0000

The Bio-Rad Science Ambassador Program participated in the 2014 Bay Area Science Festival's Discovery Days at AT&T Park event. See one volunteer Science Ambassador talk about conducting a real DNA experiment with students.

The post You Get to Do This? – The Bio-Rad Science Ambassador Program at the 2014 Bay Area Science Festival first appeared on Bio-Radiations.

Now I Have My Own DNA – The Bio-Rad Science Ambassador Program at the 2014 Bay Area Science Festival

Bioradiations Staff — Tue, 09 Dec 2014 20:00:28 +0000

See a range of students talk about the unique experience of extracting their own DNA, and one volunteer Science Ambassador talk about conducting a real DNA experiment with students.

The post Now I Have My Own DNA – The Bio-Rad Science Ambassador Program at the 2014 Bay Area Science Festival first appeared on Bio-Radiations.

Using Droplet Digital™ PCR to Monitor Environmental Contaminants in Water

Bioradiations Staff — Wed, 15 Oct 2014 19:00:10 +0000

South of Los Angeles, near some of America’s most famous beaches, one small agency is working on new methods for coastal water monitoring. Watch this video and see how scientists from SCCWRP, the Southern California Coastal Water Research Project, are using Droplet Digital PCR to watch over swimmer safety and ensure a clean environment.

The post Using Droplet Digital™ PCR to Monitor Environmental Contaminants in Water first appeared on Bio-Radiations.

Using the ChemiDoc Touch Imaging System to Find Leukemia Targets at UCSF

Bioradiations Staff — Thu, 09 Oct 2014 00:50:18 +0000

Discover how researcher Ernesto Diaz-Flores uses the ChemiDoc Touch Imaging System as he investigates therapeutic targets for a subtype of childhood leukemia. An avid photographer, Diaz-Flores also talks about the ...

The post Using the ChemiDoc Touch Imaging System to Find Leukemia Targets at UCSF first appeared on Bio-Radiations.

Bio-Rad’s S3 Cell Sorter Development: Redesigning Cell Sorting Technology

Bioradiations Staff — Wed, 08 Oct 2014 00:54:43 +0000

Take a look into the development of Bio-Rad’s S3 Cell Sorter, and see the fresh approach to cell sorting technology that resulted in an innovative new design.

The post Bio-Rad’s S3 Cell Sorter Development: Redesigning Cell Sorting Technology first appeared on Bio-Radiations.

Modeling Natural Killer Cell Receptors with the NGC Chromatography System

Bioradiations Staff — Tue, 07 Oct 2014 00:58:37 +0000

See how researcher Petr Novák, a structural biologist in Prague, Czech Republic, has accelerated his effort to characterize complex receptor molecules by integrating the NGC chromatography system into his lab’s ...

The post Modeling Natural Killer Cell Receptors with the NGC Chromatography System first appeared on Bio-Radiations.

Troubleshooting the Bio-Plex® 200 Multiplex Immunoassay System: Device Time-Out

Bioradiations Staff — Thu, 12 Jun 2014 19:00:40 +0000

A “device time-out” message on the Bio-Plex^® 200 System occurs when the instrument’s needle or probe cannot move correctly. Watch this video for several troubleshooting steps to try when this message occurs.

The post Troubleshooting the Bio-Plex^® 200 Multiplex Immunoassay System: Device Time-Out first appeared on Bio-Radiations.

Troubleshooting the Bio-Plex® 200 Multiplex Immunoassay System: HTF Alarm

Bioradiations Staff — Tue, 10 Jun 2014 19:00:30 +0000

The high-throughput fluidics (HTF) alarm on the Bio-Plex^® 200 System indicates a problem with the instrument’s sheath fluid delivery system. See the actions needed to quickly resolve potential issues with this system and get back to your research!

The post Troubleshooting the Bio-Plex^® 200 Multiplex Immunoassay System: HTF Alarm first appeared on Bio-Radiations.

Troubleshooting the Bio-Plex® 200 Multiplex Immunoassay System: Device Failed to Pressurize

Bioradiations Staff — Tue, 10 Jun 2014 17:55:20 +0000

During calibration of your Bio-Plex^® 200 System, you may receive a “failed to pressurize message.” In this short video, get some easy fixes for the most common issues prompting this message.

The post Troubleshooting the Bio-Plex^® 200 Multiplex Immunoassay System: Device Failed to Pressurize first appeared on Bio-Radiations.

How to Remove Stripes from a Gel Image — ChemiDoc™ Imager Filter Alignment

Bioradiations Staff — Sat, 31 May 2014 23:10:56 +0000

Usually when stripes appear on a gel image produced with a ChemiDoc XRS+ or ChemiDoc MP Imaging System, a misaligned filter is the cause. Learn the simple steps to correct this issue with this video from Bench Partners.

The post How to Remove Stripes from a Gel Image — ChemiDoc™ Imager Filter Alignment first appeared on Bio-Radiations.

TC20™ and TC10™ Cell Counters – Cleaning the Print Heads for Clear Printed Results

Bioradiations Staff — Mon, 07 Apr 2014 20:11:39 +0000

Most problems with misaligned printouts on the printer supplied with the TC20 and TC10 cell counters can be solved by cleaning the print heads. In this short video, find out the fast, easy, and effective way to clean these print heads so you can get back to your research!

The post TC20™ and TC10™ Cell Counters – Cleaning the Print Heads for Clear Printed Results first appeared on Bio-Radiations.

Bio-Rad Supply Center — How-To Tips for Setting Up

Bioradiations Staff — Tue, 11 Mar 2014 22:09:50 +0000

Learn the best practices and tips for setting up your Bio-Rad Supply Center.

The post Bio-Rad Supply Center — How-To Tips for Setting Up first appeared on Bio-Radiations.

Bio-Rad Supply Center — How-To Tips for Taking Inventory

Bioradiations Staff — Tue, 11 Mar 2014 20:46:07 +0000

In this new video series, Bio-Rad offers answers for some your most frequently asked questions. This installment covers setting up and taking inventory of your Bio-Rad Supply Center.

The post Bio-Rad Supply Center — How-To Tips for Taking Inventory first appeared on Bio-Radiations.

Casting Polyacrylamide Gels with TGX™ and TGX Stain-Free™ FastCast™ Acrylamide Kits

Bioradiations Staff — Tue, 14 Jan 2014 20:19:42 +0000

Want a streamlined, easy workflow for hand casting polyacrylamide gels? This tutorial video shows how to use Bio-Rad’s new FastCast™ acrylamide kits to hand cast gels, saving time while providing the benefits of the latest precast gel chemistries.

The post Casting Polyacrylamide Gels with TGX™ and TGX Stain-Free™ FastCast™ Acrylamide Kits first appeared on Bio-Radiations.

Stand Up Against Downtime

Bioradiations Staff — Mon, 11 Nov 2013 20:00:17 +0000

Facing adversity with humor, some chromatographers are drawing on the healing power of laughter to deal with the frustrations of chromatography systems that just won’t work.

The post Stand Up Against Downtime first appeared on Bio-Radiations.

The Aha! Moment – Bio Rad Science Ambassadors at the 2013 Day of Innovation

Bioradiations Staff — Tue, 08 Oct 2013 19:00:43 +0000

Enthusiastic students describe the fun they had with the Science Ambassador DNA experiment.

The post The Aha! Moment – Bio Rad Science Ambassadors at the 2013 Day of Innovation first appeared on Bio-Radiations.

Learning Curve Blues

Bioradiations Staff — Tue, 08 Oct 2013 19:00:18 +0000

This researcher sings a tune many will recognize from their own frustrations with overly complex chromatography instruments. The NGC™ chromatography system offers a simple, user-friendly interface so even students with little experience will beat the “learning curve blues.”

The post Learning Curve Blues first appeared on Bio-Radiations.

Breaking Leukemia’s Limits of Detection with Droplet Digital™ PCR

Bioradiations Staff — Mon, 16 Sep 2013 21:13:12 +0000

Prof. Alec Morley, a pioneer in digital PCR, describes his use of Droplet Digital PCR (ddPCR™) technology to advance the diagnosis and treatment of leukemia. Morley and his colleagues at Flinders University and Medical Center in Adelaide, South Australia previously developed a digital PCR method for the early detection of residual acute lymphoblastic leukemia (ALL). Learn how Morley is now using Bio-Rad's ddPCR technology to develop a diagnostic test for monitoring chronic myeloid leukemia.

The post Breaking Leukemia’s Limits of Detection with Droplet Digital™ PCR first appeared on Bio-Radiations.

Bench Buzz – Protein Purification Product Testers

Bioradiations Staff — Tue, 10 Sep 2013 19:00:32 +0000

Meet Janna and Tomas. After hearing competing claims about the scalability of next-generation chromatography systems, this dynamic duo took it upon themselves to discover the truth. Now let's face it, when you think of protein purification you don't usually think of good times. But somehow Janna and Tomas manage to keep the mood light even as they put the systems to the test by simulating changing protein purification needs. Their conclusion? Vote Yes for Better Chromatography. Vote Yes for Bio-Rad.

The post Bench Buzz – Protein Purification Product Testers first appeared on Bio-Radiations.

Buying a New Preparative Protein Purification System – You Have a New Choice

Bioradiations Staff — Tue, 13 Aug 2013 19:00:44 +0000

A day in the life of Maria, a post-graduate scientist. Both Maria and her PI are annoyed with their unreliable, out-dated protein purification system, and her PI asks Maria to buy them a new one. She struggles to find a system that meets all their needs until she remembers that Bio-Rad has a new next-generation chromatography system that will work for everyone!

The post Buying a New Preparative Protein Purification System – You Have a New Choice first appeared on Bio-Radiations.

Vote Yes for Better Chromatography — The Results Are In!

Bioradiations Staff — Tue, 09 Jul 2013 19:00:16 +0000

Watch the protein purification election night special parody! Find out which chromatography system wins. Laugh Out Loud at the terrible protein purification "pundit" and Vote Yes for Better Chromatography "Fanatics." Learn what values and system features were appreciated most by voters.

The post Vote Yes for Better Chromatography — The Results Are In! first appeared on Bio-Radiations.

Revealing BRCA2 Pathways in Cancer with Bio-Rad’s V3 Western Workflow™

Bioradiations Staff — Thu, 13 Jun 2013 19:00:34 +0000

Research led by Prof. Ryan Jensen at Yale Medical School focuses on elucidating the links between BRCA gene mutations and breast cancer. Learn how researchers in his lab use Bio-Rad's V3 Western Workflow to study interactions between BRCA proteins and the DNA repair protein RAD51. Understanding how these proteins interact in carcinogenesis and tumor growth will provide a new understanding of breast cancer mechanisms that could lead to new therapies.

The post Revealing BRCA2 Pathways in Cancer with Bio-Rad’s V3 Western Workflow™ first appeared on Bio-Radiations.

T100™ Thermal Cycler – Endorsed by Customers around the World

Bioradiations Staff — Thu, 25 Apr 2013 19:00:20 +0000

Life science researchers all over the world use the T100 thermal cycler in their daily routine. In this video, users describe how it saves them time and helps them consistently obtain high-quality data.

The post T100™ Thermal Cycler – Endorsed by Customers around the World first appeared on Bio-Radiations.

Investigating Protein Translation with the NGC™ Chromatography System

Bioradiations Staff — Thu, 14 Feb 2013 20:00:55 +0000

The Fraser lab at University of California Davis tested Bio-Rad’s NGC system for the purification of ribosomal complex proteins in their studies of protein translation mechanisms. The NGC system enabled these researchers to significantly increase their protein purification throughput and save valuable time in the lab.

The post Investigating Protein Translation with the NGC™ Chromatography System first appeared on Bio-Radiations.

ChemiDoc™ MP Imaging System Testimonial — KAIST, South Korea (full version)

Bioradiations Staff — Wed, 14 Nov 2012 20:00:03 +0000

Learn how scientists in the Gene Regulation Laboratory at the Korea Advanced Institute of Science and Technology (KAIST) use the ChemiDoc MP imaging system in their work investigating the molecular machinery involved in epigenetic gene regulation.

The post ChemiDoc™ MP Imaging System Testimonial — KAIST, South Korea (full version) first appeared on Bio-Radiations.

ChemiDoc™ MP Imaging System Testimonial — Erlangen, Germany (full version)

Bioradiations Staff — Fri, 14 Sep 2012 19:00:29 +0000

Learn how scientists in the Department of Animal Physiology at the University of Erlangen in Erlangen, Germany use the ChemiDoc MP imaging system in their work investigating sensory systems, in particular, the eye.

The post ChemiDoc™ MP Imaging System Testimonial — Erlangen, Germany (full version) first appeared on Bio-Radiations.

Bio-Plex® Multiplex System is Key in Novel Melanoma Therapeutics Study

Bioradiations Staff — Wed, 15 Aug 2012 19:00:33 +0000

Researchers at the Immaculate Dermopathic Institute (IDI-IRCCS, Rome) are using Bio-Plex technology in developing new anti-proliferation molecules and markers at the early stages of melanoma pathology. Dr Antonio Facchiano discusses how Bio-Plex has expedited the lab’s research.

The post Bio-Plex^® Multiplex System is Key in Novel Melanoma Therapeutics Study first appeared on Bio-Radiations.

PDQuest™ Software Tutorials

Bioradiations Staff — Wed, 18 Jul 2012 19:00:24 +0000

The nine PDQuest tutorials are chapterized so you can focus on what you want to learn. Each video runs from 3 to 9 minutes and features callout boxes that highlight important information to complement the audio explanations.

The post PDQuest™ Software Tutorials first appeared on Bio-Radiations.

QX100™ Droplet Digital™ ddPCR™ System at Sangamo BioSciences

Bioradiations Staff — Fri, 13 Jul 2012 22:36:02 +0000

Researchers at Sangamo BioSciences, Inc. explain the benefits of using third generation PCR as it applies to their research in the field of personalized medicine. Watch to see the latest generation of quantitative PCR in action.

The post QX100™ Droplet Digital™ ddPCR™ System at Sangamo BioSciences first appeared on Bio-Radiations.

V3 Western Workflow™

Bioradiations Staff — Fri, 11 May 2012 19:00:44 +0000

Bio-Rad’s five-step western blotting workflow incorporates traditional blotting techniques with innovative technology, allowing quick confirmation of gel runs and blot transfers, and simplifying protein normalization. See how it works.

The post V3 Western Workflow™ first appeared on Bio-Radiations.

The QX100™ Droplet Digital™ PCR System Workflow

Bioradiations Staff — Mon, 16 Apr 2012 19:00:10 +0000

Watch the step-by-step workflow for absolute quantification of DNA molecules using the third generation droplet digital PCR technology.

The post The QX100™ Droplet Digital™ PCR System Workflow first appeared on Bio-Radiations.

Bio-Plex® System in Korea

Bioradiations Staff — Wed, 14 Mar 2012 19:00:31 +0000

Dr Hunseok Lee of Seoul National University explains why it was advantageous for him to use the Bio-Plex system to measure cytokine levels in patients administered with the new cancer vaccine that his laboratory has developed.

The post Bio-Plex^® System in Korea first appeared on Bio-Radiations.

Mini-PROTEAN® TGX™ Gels — Customer Testimonials

Bioradiations Staff — Tue, 06 Mar 2012 20:00:15 +0000

Scientists from UCSD, UCD, The Salk Institute, and the University of Alabama talk about the speed, performance, and quality of electrophoresis runs using the Mini-PROTEAN TGX gels in their labs.

The post Mini-PROTEAN^® TGX™ Gels — Customer Testimonials first appeared on Bio-Radiations.

Bio-Rad Automated Supply Center in Action

Bioradiations Staff — Fri, 10 Feb 2012 20:00:09 +0000

Automated supply centers reduce paper and packaging waste, apart from providing convenience. As part of its sustainability efforts, Bio-Rad is increasing the number of its supply center sites. The video describes how the supply center works.

The post Bio-Rad Automated Supply Center in Action first appeared on Bio-Radiations.

PROTEAN® i12™ IEF System Introduction

Bioradiations Staff — Mon, 12 Dec 2011 20:00:30 +0000

Bio-Rad’s PROTEAN i12 IEF system is specially designed for running different sample types, different gradients, and multiple 2-D electrophoresis protocols at the same time. Watch the video to learn about all the new features of this IEF system.

The post PROTEAN^® i12™ IEF System Introduction first appeared on Bio-Radiations.

Bio-Plex® System Bench to Bedside

Bioradiations Staff — Tue, 30 Aug 2011 19:00:21 +0000

Watch how the Bio-Plex® suspension array system has contributed to research findings in Dr Francis Spinale and Dr Steven Kornblau's laboratories that have the potential to impact screening and treatment of disease.

The post Bio-Plex^® System Bench to Bedside first appeared on Bio-Radiations.

Gel Doc™ EZ Imaging System Customer Testimonial

Bioradiations Staff — Mon, 29 Aug 2011 19:00:39 +0000

Harvard Medical School Postdoctoral student Sririam Kosuri explains how the Gel Doc EZ system has changed the way researchers image gels in the George Church lab at Harvard Medical School’s Wyss Institute.

The post Gel Doc™ EZ Imaging System Customer Testimonial first appeared on Bio-Radiations.

Gel Doc™ EZ Testimonial — UCSD

Bioradiations Staff — Sun, 28 Aug 2011 19:00:28 +0000

Assistant Project Scientist Dr. Dorota Krawczyk, PhD, at the Geoff Rosenfeld Laboratory at the University of California, San Diego, describes how easy it is to use the Gel Doc EZ system.

The post Gel Doc™ EZ Testimonial — UCSD first appeared on Bio-Radiations.

Innovating Electrophoresis with Precast Gels

Bioradiations Staff — Fri, 26 Aug 2011 19:00:59 +0000

Setting new standards for consistency and speed in the electrophoresis workflow.

The post Innovating Electrophoresis with Precast Gels first appeared on Bio-Radiations.

Trans-Blot Turbo Instructional Video

Bioradiations Staff — Wed, 24 Aug 2011 19:00:02 +0000

Instructional video to guide you through the features, benefits, and operation of the Trans-Blot Turbo system.

The post Trans-Blot Turbo Instructional Video first appeared on Bio-Radiations.

Trans-Blot® Turbo™ System vs. the iBlot System

Bioradiations Staff — Tue, 23 Aug 2011 19:00:44 +0000

Battle of the blotters: see how the Trans-Blot Turbo system performs compared to the iBlot dry blotting system.

The post Trans-Blot^® Turbo™ System vs. the iBlot System first appeared on Bio-Radiations.

Trans-Blot® Turbo™ System vs. Traditional Blotting Techniques

Bioradiations Staff — Mon, 22 Aug 2011 19:00:37 +0000

See how the Trans-Blot Turbo system measures up against traditional blotting techniques.

The post Trans-Blot^® Turbo™ System vs. Traditional Blotting Techniques first appeared on Bio-Radiations.

ProteOn™ XPR36 Protein Interaction Array System

Bioradiations Staff — Sat, 11 Jun 2011 19:00:59 +0000

An overview of how the ProteOn XPR36 protein interaction array system can benefit your surface-plasmon reasonance-based research.

The post ProteOn™ XPR36 Protein Interaction Array System first appeared on Bio-Radiations.

Using the TC10™ Automated Cell Counter

Bioradiations Staff — Thu, 09 Jun 2011 19:00:22 +0000

A better, more accurate, easier way to count cells than a traditional hemocytometer — learn how this automated system works.

The post Using the TC10™ Automated Cell Counter first appeared on Bio-Radiations.

The T100™ Thermal Cycler

Bioradiations Staff — Wed, 01 Jun 2011 19:00:52 +0000

Why the T100 thermal cycler is the smart choice for your PCR.

The post The T100™ Thermal Cycler first appeared on Bio-Radiations.

Trans-Blot® Turbo™ System

Bioradiations Staff — Wed, 01 Jun 2011 19:00:46 +0000

Step-by-step with the Trans-Blot Turbo system — from building the blot sandwich to programming the run.

The post Trans-Blot^® Turbo™ System first appeared on Bio-Radiations.

1000-Series Touch Thermal Cyclers

Bioradiations Staff — Wed, 01 Jun 2011 19:00:00 +0000

Touch the future of PCR; introducing the 1000-series Touch thermal cyclers.

The post 1000-Series Touch Thermal Cyclers first appeared on Bio-Radiations.

One of the Best Places to Work in 2011

Bioradiations Staff — Tue, 31 May 2011 19:00:38 +0000

The people behind the science – the reason Bio-Rad has been named one of the "2011 Best Places to Work in the Bay Area" by the San Francisco Business Times.

The post One of the Best Places to Work in 2011 first appeared on Bio-Radiations.