Product Highlights | Bio-Radiations

Advancements in CMOS Sensors for Scientific Imaging

Bioradiations Staff — Tue, 13 May 2025 18:22:04 +0000

For years, CCD sensors, known for their high-quality imaging capabilities, have been the gold standard in scientific instrumentation. However, recent advancements in CMOS sensors have positioned them as a cost-effective and competitive alternative that is quickly gaining traction in the field. In this article, we delve into the strengths and applications of CCD and CMOS sensors, exploring how this shift in technology is reshaping the digital imaging landscape.

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As Easy as 1, 2, 3: Achieving Purification Success with a New Two-Mode Chromatography Resin

Bioradiations Staff — Tue, 13 May 2025 18:21:43 +0000

A common misconception is that stronger is always better. However, Nuvia wPrime 2A Media, a weak anion exchange hydrophobic interaction (AEX-HIC) mixed-mode chromatography resin, has won over purification scientists. Read about diverse use cases for Nuvia wPrime 2A Media and see the data for yourself.

The post As Easy as 1, 2, 3: Achieving Purification Success with a New Two-Mode Chromatography Resin first appeared on Bio-Radiations.

Advancing Oncology Research with Immune Response Studies: The Role of xMAP-Based Bio-Plex Multiplex Immunoassays

Bioradiations Staff — Tue, 12 Nov 2024 18:03:10 +0000

In the rapidly evolving field of cancer research, understanding the complex interplay between tumors and the immune system is essential for developing effective therapies. Bio-Plex Multiplex Immunoassays, for research use only and powered by Luminex xMAP technology, provide a cutting-edge tool for simultaneously measuring multiple immune biomarkers. Learn how these research tools are paving the way for development of personalized cancer treatments in the future.

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Introducing the ChemiDoc Go Imaging System: Modern Gel and Western Blot Imaging

Bioradiations Staff — Tue, 13 Aug 2024 22:05:03 +0000

A groundbreaking addition to imaging technology has arrived — the ChemiDoc Go Imaging System. The ChemiDoc Go Imaging System is tailored for both gel and western blot imaging, including chemiluminescence and StarBright Blue fluorescent detection. Its compatibility with various trays and LED configurations ensures optimal performance across different experimental setups, including gel excision, nucleic acid staining, and protein detection.

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Enhancing Biotherapeutic Purification Workflows with Mixed-Mode Chromatography

Bioradiations Staff — Tue, 13 Aug 2024 21:41:29 +0000

As biotherapeutic modalities have diversified and production processes become more advanced, an evolution in purification strategies is also needed. Modern biotherapeutic purification must be capable of removing multiple types of impurities without compromising yield or quality, in a cost-effective manner. To meet these needs, many are turning to mixed-mode chromatography.

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7 Ways Custom PCR Reagents and Plastics Fuel Product Development

Bioradiations Staff — Tue, 14 Nov 2023 20:03:09 +0000

One-size-fits-all solutions cannot address the full range of molecular biology needs in areas such as biotech, biopharma, or molecular diagnostics. When your requirements exceed the existing offerings of reagents and plastics on the market, Bio-Rad can partner with you and provide custom solutions. For a deeper look into these customization opportunities, we spoke with Anna Lai, manager of Bio-Rad's custom reagents program, and Jennifer Placek, who manages the company's custom plastics.

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Automated Multicolumn Monoclonal Antibody Purification

Bioradiations Staff — Tue, 14 Nov 2023 19:56:23 +0000

The current gold standard in monoclonal antibody purification for most researchers is affinity purification with Protein A or G followed by size exclusion chromatography (SEC). Although robust and highly effective, this workflow does have critical pain points and inefficiencies, leaving researchers to feel that they must oversee every step of their workflow, not leaving their chromatography system unattended for more than a few minutes.

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Measure Neutralizing Antibodies against Any SARS-CoV-2 Variant in 1 Day

Bioradiations Staff — Tue, 11 Oct 2022 19:05:50 +0000

Current vaccines against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have reduced the severity of the coronavirus disease 2019 (COVID-19). However, the drastic and quick evolution of the virus poses challenges to the development of durable and efficacious therapeutics for vaccine and antibody developers alike. See how the Bio-Plex Pro Human SARS-CoV-2 Neutralization Antibody Custom Assay Developer Kit speeds up the qualitative measurement of neutralizing antibodies (NAbs) against new SARS-CoV-2 variants, removing a roadblock in COVID-19 therapeutic development.

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Take the Expressway to RNA Library Prep

Bioradiations Staff — Wed, 13 Jul 2022 02:18:43 +0000

RNA-Seq library preparation is a manually intensive, time-consuming process prone to bias from the multiple enzymes required. So, how can you trust your sequencing results? Bio-Rad is revolutionizing RNA-Seq library prep with the SEQuoia Express Stranded RNA Library Prep Kit – a three-hour, three-tube solution eliminating the need for multiple enzymes and reducing both the number of pipetting steps and protocol time. The key is an engineered, proprietary retrotransposon called SEQzyme. With this serial template jumping, or continuous synthesis, reaction you can obtain an unbiased, stranded RNA-Seq library constructed to accurately represent both messenger and non-coding RNA from your sample.

The post Take the Expressway to RNA Library Prep first appeared on Bio-Radiations.

Powering Antibody Production and Purification with the NGC Chromatography System

Bioradiations Staff — Tue, 12 Apr 2022 16:22:05 +0000

For this article, we spoke with Vera Dreyfuss of evitria AG, an antibody expression services provider based in Switzerland, about the role that the NGC Chromatography System has played in powering the growth and success of the company.

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Viral RNA Preparation for Molecular Pathogen Detection: A New Application for Chelex 100 Resin and InstaGene Matrix

Bioradiations Staff — Tue, 11 Jan 2022 08:56:31 +0000

Although vaccines have helped alleviate the negative impact of COVID-19, its persistence across many areas of the globe reveals a continuous need for rapid, accurate, and economical COVID-19 testing. But is it even possible to isolate and detect viral RNA rapidly and economically? Here we highlight a repurposed tool for improved COVID-19 detection: Chelex 100 Resin and the related InstaGene Matrix for rapid, cost-effective viral RNA preservation and detection.

The post Viral RNA Preparation for Molecular Pathogen Detection: A New Application for Chelex 100 Resin and InstaGene Matrix first appeared on Bio-Radiations.

Neutralizing Antibody Assays for SARS-CoV-2 Variant Studies

Bioradiations Staff — Tue, 11 Jan 2022 08:41:37 +0000

With COVID-19 vaccines now widely available, case numbers in many areas are falling. But the question remains: How long does vaccine-induced immunity last? Measuring isotype-specific antibodies against SARS-CoV-2 and the effectiveness of neutralizing antibodies against variants can help us better understand the duration and breadth of the humoral response. These data are critical to aid public health researchers and inform development decisions for vaccines and therapeutics. Read about the new Bio-Plex Pro Human SARS-CoV-2 Variant Neutralization Antibody 11-Plex Panel.

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Beyond the Spec Sheet: Evaluating New qPCR Instrumentation

Bioradiations Staff — Tue, 14 Sep 2021 16:36:05 +0000

Whether you are part of a small academic lab or a multinational corporation, upgrading to a new quantitative PCR (qPCR) system can be both exciting and daunting. How will the new system perform compared to your current platform? Will your existing workflows translate smoothly? Read on to learn about our recent bridging study for users considering upgrading to the new CFX Opus Real-Time PCR System.

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Introducing the GelDoc Go Imaging System

Bioradiations Staff — Tue, 14 Sep 2021 16:35:09 +0000

The next iteration of Bio-Rad Gel Documentation Systems has arrived. The GelDoc Go Imaging System gives you a benchtop imaging solution that enables gel documentation in three simple steps. Acquire high-resolution, publication-quality images of nucleic acid gels, protein gels, and colorimetric blots. Image up to four mini gels at once with the large imaging area, and easily set up and control the GelDoc Go Imaging System with Image Lab Touch Software. Read more about the compact, easy-to-use GelDoc Go System.

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Retain Rare Transcripts While Depleting Ribosomal RNA

Bioradiations Staff — Wed, 09 Jun 2021 00:40:20 +0000

Bio-Rad is excited to announce the launch of SEQuoia RiboDepletion Kit, the newest product in the SEQuoia portfolio of RNA-Seq sample preparation products. This is a stand-alone, post–library depletion kit that eliminates RNA-Seq library fragments that originated from ribosomal RNA sequences. The kit exhibits superior performance in retaining small RNAs while minimizing the loss of rare transcripts and RNA from limited samples, providing a better approach to whole transcriptome profiling. Furthermore, the cost of rRNA depletion can be significantly reduced by pooling and depleting multiple libraries in a single ribodepletion reaction.

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Introducing the Bio-Plex Pro Human IgG SARS-CoV-2 Serology Assays

Bioradiations Staff — Mon, 08 Mar 2021 22:00:03 +0000

Meet our newest product supporting the fight against SARS-CoV-2: the Bio-Plex Pro Human IgG SARS-CoV-2 N/RBD/S1/S2 4-Plex Panel. This qualitative multiplex immunoassay kit quickly and efficiently detects IgG antibodies against four SARS-CoV-2 antigens (nucleocapsid, receptor binding domain, spike 1, and spike 2).

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Countering COVID-19 with the Launch of Two New RT-PCR Kits

Bioradiations Staff — Mon, 08 Mar 2021 21:24:35 +0000

Bio-Rad is proud to introduce our new RT-PCR testing kits for COVID-19. These all-in-one kits are designed for sensitive, specific detection of SARS-CoV-2 alone, or simultaneous detection of SARS-CoV-2, influenza A, and influenza B. Read on to learn about each kit’s features.

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Introducing the Reliance Select cDNA Synthesis Kit

Bioradiations Staff — Tue, 08 Dec 2020 18:47:44 +0000

The Reliance Select cDNA Synthesis Kit is the newest reverse transcription product from Bio-Rad. This high-performance kit features Reliance Reverse Transcriptase, a novel chimeric enzyme that delivers superior results across a broad dynamic range, even with challenging samples. The Reliance Select cDNA Synthesis Kit delivers more accurate reverse transcription quantitative PCR (RT-qPCR) results, even from samples containing PCR inhibitors or degraded RNA.

The post Introducing the Reliance Select cDNA Synthesis Kit first appeared on Bio-Radiations.

Introducing the CFX Opus Real-Time PCR Systems — A Modern Take on Bio-Rad Consistency

Bioradiations Staff — Wed, 09 Sep 2020 21:55:33 +0000

Coming soon: The next iteration in Bio-Rad’s tradition of qPCR excellence. The compact CFX Opus Real-Time PCR System is more connected, consistent, and easier to use than ever before, and is available in 96- and 384-well formats. The CFX Opus Systems launch with our new BR.io cloud platform and the latest version of CFX Maestro Software, for complete instrument control and data analysis capabilities.

The post Introducing the CFX Opus Real-Time PCR Systems —
A Modern Take on Bio-Rad Consistency first appeared on Bio-Radiations.

Analyzing Carbohydrates

Bioradiations Staff — Wed, 10 Jun 2020 17:32:13 +0000

Carbohydrates are among the most important components of foods, providing energy as well as flavor, texture, and other physical properties. Identification and quantification of carbohydrates in food is commonly performed using high-performance liquid chromatography. Bio-Rad Aminex Ion Exchange Resins have become the industry standard for carbohydrate and organic acid analysis.

The post Analyzing Carbohydrates first appeared on Bio-Radiations.

A Powerful Solution for NGS RNA Library Preparation

Bioradiations Staff — Wed, 15 Jan 2020 22:13:41 +0000

The SEQuoia Complete Stranded RNA Library Prep Kit is the newest addition to Bio-Rad’s next-generation sequencing (NGS) space. Capturing long and short RNAs and validated with FFPE and low-quality samples, see why it should be your top choice for high-performance RNA-Seq library prep.

The post A Powerful Solution for NGS RNA Library Preparation first appeared on Bio-Radiations.

A Resin Built Specifically for Large Biomolecule Purifications

Bioradiations Staff — Tue, 10 Jul 2018 21:35:45 +0000

Nuvia HP-Q is a high-performance strong anion exchange resin designed for purification of large biomolecules. See how its optimized particle and pore size leads to high target recovery and high-throughput purifications.

The post A Resin Built Specifically for Large Biomolecule Purifications first appeared on Bio-Radiations.

Improve Your Protein Purification Process Economy with CHT Ceramic Hydroxyapatite XT Media

Bioradiations Staff — Tue, 12 Jun 2018 22:50:52 +0000

CHT Ceramic Hydroxyapatite XT Media is designed for repeated use and exceptional resolution. It combines exceptional functionality with a long column life to help achieve high productivity and improved process economics. See how CHT XT can improve your protein purification.

The post Improve Your Protein Purification Process Economy with CHT Ceramic Hydroxyapatite XT Media first appeared on Bio-Radiations.

Improve the Quality of Your Cell Analysis with the ZE5™ Cell Analyzer

Bioradiations Staff — Wed, 11 Apr 2018 19:57:40 +0000

Cell analysis is a crucial first step in many experiments so a reliable, flexible, and quick cell analyzer that produces high-resolution, reproducible results is what every lab needs. See how the ZE5™ Cell Analyzer can help improve the quality of your cell analysis experiments, instill confidence in your results, and shorten the time to publish.

The post Improve the Quality of Your Cell Analysis with the ZE5™ Cell Analyzer first appeared on Bio-Radiations.

High-Throughput Single-Cell RNA-Seq of Large Cells and Nuclei

Bioradiations Staff — Wed, 14 Mar 2018 16:41:55 +0000

mRNA-FISH, single-cell RT-qPCR, and single-cell RNA sequencing (RNA-Seq) have emerged as popular single-cell transcriptomics technologies. See how the Illumina® Bio-Rad® Single-Cell Sequencing Solution overcomes many of the challenges of currently available platforms by allowing high-throughput and scalable sequencing of even the most challenging sample types, including large cells and small species such as nuclei.

The post High-Throughput Single-Cell RNA-Seq of Large Cells and Nuclei first appeared on Bio-Radiations.

Introducing the NGC™ Fraction Collector for Discovery to Process-Scale Protein Purification

Bioradiations Staff — Tue, 13 Feb 2018 23:59:43 +0000

The newly launched NGC™ Fraction Collector, together with ChromLab™ 5.0 Software, have enhanced the functionality of the NGC Chromatography System to provide the flexibility and collection capacity needed for any application, from discovery to scale up. See how the NGC System can help you improve your protein purification process.

The post Introducing the NGC™ Fraction Collector for Discovery to Process-Scale Protein Purification first appeared on Bio-Radiations.

An IMAC Resin for a Highly Productive Histidine-Tagged Protein Purification Process

Bioradiations Staff — Wed, 09 Aug 2017 18:30:59 +0000

One of the advancements in protein purification has been to tag the protein of interest with a short sequence that can bind to an immobilized matrix and aid purification. Bio-Rad’s new IMAC resin offers a host of advantages for the purification of histidine-tagged proteins. Learn more about this resin and see how it can enhance the efficiency of your protein purification workflow.

The post An IMAC Resin for a Highly Productive Histidine-Tagged Protein Purification Process first appeared on Bio-Radiations.

Get More Answers from Your Mouse with the Bio-Plex Pro™ Mouse Chemokine Panel

Bioradiations Staff — Thu, 15 Jun 2017 20:59:30 +0000

Biomarker screening can sometimes be like working in a black box. While traditional research tools focus on one protein at a time, Bio-Rad’s new Bio-Plex Pro™ Mouse Chemokine Panel can simultaneously interrogate 33 chemokines and cytokines in a single well. See how you can get more answers with this panel.

The post Get More Answers from Your Mouse with the Bio-Plex Pro™ Mouse Chemokine Panel first appeared on Bio-Radiations.

Investigating Immune Response Profiles Using Bio-Plex Pro™ Multiplex Assays

Bioradiations Staff — Wed, 15 Mar 2017 23:01:21 +0000

See how one study used Bio-Rad’s Bio-Plex Pro Human Cytokine 27-Plex Assay to investigate immune responses to an anti-viral compound in an effort to better understand vaccine efficacy.

The post Investigating Immune Response Profiles Using Bio-Plex Pro™ Multiplex Assays first appeared on Bio-Radiations.

A Superior Method for Parallel Analysis of RNA and Protein Expression from Cell Culture Lysates

Bioradiations Staff — Thu, 16 Jun 2016 23:33:14 +0000

It is imperative to analyze both the transcriptional and translational profiles for a complete understanding of the functioning of genes. Here we describe a simple protocol that enables parallel analysis of both RNA and protein from single cell culture lysates. See how this workflow could save time and money and yield more reliable data than the traditional protocols used.

The post A Superior Method for Parallel Analysis of RNA and Protein Expression from Cell Culture Lysates first appeared on Bio-Radiations.

Purifying Difficult-to-Purify Proteins

Bioradiations Staff — Thu, 16 Jun 2016 23:12:00 +0000

Protein purification becomes a challenging step for applications requiring high protein concentrations (such as structural biology studies). This is also true for researchers purifying integral membranes proteins and untagged proteins from native sources. Here we provide some useful tips for selecting the proper resins, optimizing conditions and developing effective strategies to tackle the challenges associated with such difficult-to-purify proteins.

The post Purifying Difficult-to-Purify Proteins first appeared on Bio-Radiations.

The Importance of Quality PCR Plastics

Bioradiations Staff — Wed, 11 May 2016 20:44:19 +0000

Do we ever think seriously about PCR plates, seals, and tubes as contributing to the quality of our gene expression results? Chances are that these PCR plastics are viewed just as labware by most people. In this article we bring out how simple factors, such as PCR plate rigidity, color of the wells, and adhesiveness of plate seals, can affect your gene expression results and show why it is important to use quality PCR plastics.

The post The Importance of Quality PCR Plastics first appeared on Bio-Radiations.

How Do You Automate a Multicolumn Protein Purification?

Bioradiations Staff — Wed, 11 May 2016 20:37:44 +0000

Multicolumn purifications are tedious and the manual operations during this process introduce variabilities, affecting the success of purification and reproducibility of results. This whiteboard animation explains how an automated multi-dimensional chromatography method can make this an easier process with very high success rates.

The post How Do You Automate a Multicolumn Protein Purification? first appeared on Bio-Radiations.

Western Blot Detection without Interfering IgGs: A Mere Fantasy or a Real Possibility?

Bioradiations Staff — Tue, 12 Apr 2016 20:00:23 +0000

Interference from IgG heavy (~ 50 kD) or light (~25 kD) chains is very common when trying to visualize bands of immunoprecipitated proteins. If your band of interest has a molecular weight close to these, it becomes really hard to distinguish between the IgG and the band of interest. How could this be avoided? Bio-Rad’s new TidyBlot™ Western Blot Detection Reagent accomplishes this by binding exclusively to the native nondenatured antibodies rather than any IgG in the sample. Explore the performance characteristics of this new reagent.

The post Western Blot Detection without Interfering IgGs: A Mere Fantasy or a Real Possibility? first appeared on Bio-Radiations.

How Does an Antibody Qualify To Become a PrecisionAb™ Antibody?

Bioradiations Staff — Tue, 08 Mar 2016 18:34:37 +0000

Not all antibodies are created equal. Some have to work hard to qualify to become Bio-Rad’s PrecisionAb™ Antibody. Here is a diagrammatic representation of how the qualification criteria are determined.

The post How Does an Antibody Qualify To Become a PrecisionAb™ Antibody? first appeared on Bio-Radiations.

New Product Feature: gDNA-Free cDNA in Two Simple Steps

Bioradiations Staff — Tue, 09 Feb 2016 22:08:23 +0000

Removing genomic DNA contamination from cDNA preparations is a challenge. All currently available methods are time consuming, could lead to sample loss, and are not efficient. Bio-Rad’s iScript™gDNA Clear cDNA Synthesis Kit tackles these issues and makes this step effortless. This article presents the performance data of the kit and describes how simple and efficient it is to use the kit for gDNA removal.

The post New Product Feature: gDNA-Free cDNA in Two Simple Steps first appeared on Bio-Radiations.

PrecisionAb™ Antibodies: Defining New Standards for Western Blotting

Bioradiations Staff — Tue, 09 Feb 2016 22:00:24 +0000

Choosing the right primary antibody is an arduous task. A lot of standardization needs to happen before we can determine that the antibody is specific and sensitive enough for the purpose of our experiment. The new PrecisonAb™ Antibodies from Bio-Rad go through vigorous testing and validation before they are deemed suitable, thus eliminating the process of trial and error for researchers. The video describes how the PrecisionAb antibodies are developed.

The post PrecisionAb™ Antibodies: Defining New Standards for Western Blotting first appeared on Bio-Radiations.

Bio-Rad’s PrimePCR™ Assays and Panels Eliminate Multiple Steps from Your qPCR Workflow

Bioradiations Staff — Tue, 10 Nov 2015 22:33:18 +0000

A qPCR workflow involves multiple steps, each of which adds to the time and cost of the entire experiment. The PrimePCR™ Assays and Panels from Bio-Rad eliminate a number of these steps with their predesigned primers and probes and help with the assay design. See what steps they eliminate and how that would help expedite your qPCR experiment.

The post Bio-Rad’s PrimePCR™ Assays and Panels Eliminate Multiple Steps from Your qPCR Workflow first appeared on Bio-Radiations.

Bio-Rad’s Multi-D Method Addresses Unmet Chromatography Needs

Bioradiations Staff — Thu, 03 Sep 2015 00:14:06 +0000

Some of the frustrations in protein purification stem from unmet chromatography needs, such as automation, productivity, throughput, and reproducibility among others. Bio-Rad’s new Multi-D chromatography method addresses these and provides solutions to faster, efficient and more reliable protein purification.

The post Bio-Rad’s Multi-D Method Addresses Unmet Chromatography Needs first appeared on Bio-Radiations.

The Antibody Challenge: Bio-Rad’s Precise Solution

Bioradiations Staff — Tue, 11 Aug 2015 22:15:36 +0000

Why western blotting, a technique used in every day research, is still not as straightforward as it seems? Well, it’s mainly because of the antibodies. They may not work in all samples, a lot of standardization needs to be done and there are several other unknowns. Bio-Rad, the leader in western blotting, has addressed these concerns in its newest line of antibodies, the PrecisionAb™ Antibodies. See the challenges and the Bio-Rad solution.

The post The Antibody Challenge: Bio-Rad’s Precise Solution first appeared on Bio-Radiations.

Introducing the ZOE™ Fluorescent Cell Imager for Routine Cell Culture and Fluorescent Imaging Applications

Bioradiations Staff — Fri, 15 May 2015 22:06:25 +0000

Using traditional fluorescence microscopes for everyday cell imaging can be frustrating, with a lot of time spent in the darkroom mastering a highly specialized piece of equipment, all to accomplish relatively simple tasks. The ZOE Fluorescent Cell Imager eliminates the complexities of cell imaging by combining the ease of use of a personal tablet with the power of an inverted microscope. Check it out.

The post Introducing the ZOE™ Fluorescent Cell Imager for Routine Cell Culture and Fluorescent Imaging Applications first appeared on Bio-Radiations.

Brighter Precision Plus Protein™ Dual Color Standard — The Brightest Protein Marker Available

Bioradiations Staff — Tue, 10 Jun 2014 20:31:25 +0000

Take a quick look at Bio-Rad’s brighter Precision Plus Protein™ Dual Color Standard with this article comparing this standard to other available protein markers. Plus, find out why the ability to visualize a protein standard after reprobing matters to one researcher!

The post Brighter Precision Plus Protein™ Dual Color Standard — The Brightest Protein Marker Available first appeared on Bio-Radiations.

Bio-Rad’s Universal Real-Time PCR App – Everything You Need to Know about Real-Time PCR at Your Fingertips

Bioradiations Staff — Thu, 15 May 2014 23:10:06 +0000

Bio-Rad’s Universal Real-Time PCR Kits and Reagents work on all real-time PCR systems. Now you can easily compare performance data and get supporting documents for these kits and reagents using Bio-Rad’s new tablet and web app. Learn more and download the app here.

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Developing Bio-Rad’s S3™ Cell Sorter: The Great Cell Sorting Redesign

Bioradiations Staff — Thu, 15 May 2014 04:53:34 +0000

Cell sorting technology is not new. However, sometimes taking a new look at a mature technology brings unexpected results. See how we reimagined drop delay calculation, rethought software and automation, and more during the design and development of Bio-Rad’s S3 Cell Sorter.

The post Developing Bio-Rad’s S3™ Cell Sorter: The Great Cell Sorting Redesign first appeared on Bio-Radiations.

A New Breed of Cell Sorters: Bio-Rad’s S3™ Cell Sorter Appeals to the Growing Cell Biology Community

Bioradiations Staff — Tue, 11 Mar 2014 19:00:00 +0000

The S3 cell sorter is Bio-Rad’s new addition to the world of flow cytometry. Take a look at how this instrument breaks the mold for cell sorters, brings relief to investigators and core lab managers alike, and opens up exciting new research possibilities.

The post A New Breed of Cell Sorters: Bio-Rad’s S3™ Cell Sorter Appeals to the Growing Cell Biology Community first appeared on Bio-Radiations.

Bio-Rad’s FastCast™ Acrylamide Kits — It’s Time to Expect More from Your Handcast Gels

Bioradiations Staff — Tue, 12 Nov 2013 17:42:49 +0000

Hand casting polyacrylamide gels is not an easy task. It is laborious, needs lot of pre-planning and is cumbersome. Bio-Rad’s new TGX and TGX Stain-Free FastCast gel solutions not only address all these issues, but provide added benefits, such as increased speed, stain-free visualization, and quality control. Learn more about these new handcasting kits.

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Biologics Analysis Workflow™ – Delivering Increased Throughput, Sensitivity, Reproducibility, and Automation for cGMP Laboratories

Bioradiations Staff — Mon, 12 Aug 2013 17:04:33 +0000

Evaluating potential protein therapies for purity and/or identity represents a vital and highly regulated step in biological drug development. Bio-Rad’s new Biologics Analysis Workflow™ offers a high-throughput, sensitive, and reproducible solution that is cGMP-compliant.

The post Biologics Analysis Workflow™ – Delivering Increased Throughput, Sensitivity, Reproducibility, and Automation for cGMP Laboratories first appeared on Bio-Radiations.

New PrimePCR™ Probe Assays for Real-time PCR and Droplet Digital™ PCR Technologies

Bioradiations Staff — Tue, 09 Jul 2013 18:26:52 +0000

Bio-Rad’s PrimePCR probe assays gave researchers a powerful, reliable set of investigative tools utilizing SYBR® Green detection chemistry. Now Bio-Rad is adding a number of new assays to the PrimePCR portfolio, bringing the benefits of PrimePCR assays to many new applications for both real-time PCR and Droplet Digital™ PCR platforms.

The post New PrimePCR™ Probe Assays for Real-time PCR and Droplet Digital™ PCR Technologies first appeared on Bio-Radiations.

New and Improved Microplate Manager® Software for Microplate Data Acquisition and Analysis

Bioradiations Staff — Wed, 27 Mar 2013 17:16:23 +0000

Bio-Rad’s microplate readers function at their full potential when used with Microplate Manager Software. This updated version of the software features two new read modes, compatibility with the latest operating systems, and more.

The post New and Improved Microplate Manager^® Software for Microplate Data Acquisition and Analysis first appeared on Bio-Radiations.

Real-Time PCR Interactive Tutorials — From Reagent Selection to Real-Time PCR Data Analysis

Bioradiations Staff — Tue, 26 Mar 2013 22:42:42 +0000

Obtaining accurate quantitative PCR data depends on choosing and validating the proper reagents for a given experiment. These new tutorials present the knowledge base needed to understand the parameters involved in reagent selection in order to get the best results from real-time PCR procedures.

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Bio-Rad’s 2-D Electrophoresis Workflow How-To Guide, Fourth Edition, is Now Available for Download

Bioradiations Staff — Tue, 19 Mar 2013 17:57:28 +0000

Bio-Rad’s 2-D electrophoresis workflow offers better results in a shorter time. Take a detailed look at this workflow by downloading the updated edition of our How-To Guide.

The post Bio-Rad’s 2-D Electrophoresis Workflow How-To Guide, Fourth Edition, is Now Available for Download first appeared on Bio-Radiations.

Gel Doc™ EZ Imaging System — Push-Button Imaging in Just Ten Seconds

Bioradiations Staff — Tue, 08 Jan 2013 19:30:02 +0000

Bio-Rad’s innovative Gel Doc EZ imaging system features something unique that no other imaging system has – brains.

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New Premium Hard-Shell Microplate for Applied Biosystems 7500 Fast and ViiA 7 Fast Real-Time PCR systems

Bioradiations Staff — Mon, 07 Jan 2013 18:33:35 +0000

Bio-Rad introduces new Hard-Shell 96-well Semi-skirted low profile PCR plates for optimal performance with a variety of real-time PCR systems.

The post New Premium Hard-Shell Microplate for Applied Biosystems 7500 Fast and ViiA 7 Fast Real-Time PCR systems first appeared on Bio-Radiations.

New Roche LightCycler 480 Hard-Shell® Plate That Does Not Warp During Thermal Cycling

Bioradiations Staff — Fri, 14 Dec 2012 19:15:12 +0000

Stability during thermal cycling and uniformity of wells are important features in any PCR plate for obtaining reliable results. Bio-Rad’s new Hard-Shell® plates are stable, prevent warping and shrinkage, and are designed for optimal thermal transfer and recovery of samples.

The post New Roche LightCycler 480 Hard-Shell^® Plate That Does Not Warp During Thermal Cycling first appeared on Bio-Radiations.

Bio-Rad’s New S3™ Cell Sorter Automates and Simplifies Cell Sorting

Bioradiations Staff — Mon, 29 Oct 2012 19:11:32 +0000

Cell sorting is a complex and expensive process, with complicated steps requiring training. Bio-Rad’s new S3™ cell sorter is compact, easy to use, automated, affordable, and provides exceptional sort purity and yield results.

The post Bio-Rad’s New S3™ Cell Sorter Automates and Simplifies Cell Sorting first appeared on Bio-Radiations.

New CFX96 Touch™ Deep Well Real-Time PCR Instrument Enables Large-Volume qPCR Reactions

Bioradiations Staff — Sun, 28 Oct 2012 20:32:09 +0000

Large sample volumes may sometimes be needed to conduct gene expression studies. Bio-Rad’s new CFX96 Touch Deep Well™ real-time PCR detection system can run sample volumes up to 125 µl and can discriminate up to five targets simultaneously.

The post New CFX96 Touch™ Deep Well Real-Time PCR Instrument Enables Large-Volume qPCR Reactions first appeared on Bio-Radiations.

CFX Qualification Plate — A Reliable Performance Verification Tool for any CFX Real-Time PCR System

Bioradiations Staff — Fri, 26 Oct 2012 18:28:28 +0000

Verifying the performance of your real-time PCR system is crucial to obtaining reliable data from your experiments. Bio-Rad’s new CFX qualification plate comes with a quick and easy protocol that provides reliable performance verification of any real-time qPCR system.

The post CFX Qualification Plate — A Reliable Performance Verification Tool for any CFX Real-Time PCR System first appeared on Bio-Radiations.

New Semi-Automated Heat Sealer Delivers Consistent and Reliable PCR Plate Sealing

Bioradiations Staff — Mon, 08 Oct 2012 19:09:57 +0000

The PX1 PCR Plate Sealer efficiently seals microplates used in thermal cycling. This heat sealing method consistently delivers reliable data by helping eliminate sample evaporation during PCR.

The post New Semi-Automated Heat Sealer Delivers Consistent and Reliable PCR Plate Sealing first appeared on Bio-Radiations.

New TC20™ Automated Cell Counter Facilitates Quick Counting with Precision

Bioradiations Staff — Wed, 05 Sep 2012 20:10:10 +0000

Bio-Rad’s new TC20 automated cell counter is compatible with broad range of cell sizes and types such as cell lines, primary cells (from tissue or blood), and stem cells.

The post New TC20™ Automated Cell Counter Facilitates Quick Counting with Precision first appeared on Bio-Radiations.

Expect More From Your Chemiluminescent Substrate: Introducing Clarity™ Western ECL Substrate

Bioradiations Staff — Tue, 04 Sep 2012 17:08:06 +0000

Bio-Rad’s new Clarity Western ECL substrate provides high sensitivity, long signal duration, and low background even at long exposures.

The post Expect More From Your Chemiluminescent Substrate: Introducing Clarity™ Western ECL Substrate first appeared on Bio-Radiations.

Trans-Blot® Turbo™ Ready-to-Assemble (RTA) Kit Enables Economical, Rapid, and Efficient Western Blot Transfers

Bioradiations Staff — Mon, 03 Sep 2012 17:33:49 +0000

Bio-Rad’s latest semi-dry transfer system, the Trans-Blot® Turbo™, has changed the way researchers think about western blot transfers.

The post Trans-Blot^® Turbo™ Ready-to-Assemble (RTA) Kit Enables Economical, Rapid, and Efficient Western Blot Transfers first appeared on Bio-Radiations.

New and Improved CFX Manager™ Software for Real-Time PCR Data Acquisition and Analysis

Bioradiations Staff — Mon, 06 Aug 2012 17:49:28 +0000

The latest version of the CFX Manager software provides a variety of usability enhancements and powerful new data analyses so users can get the most out of each run.

The post New and Improved CFX Manager™ Software for Real-Time PCR Data Acquisition and Analysis first appeared on Bio-Radiations.

New Gradient Format Mini-PROTEAN® TGX Stain-Free™ Precast Gels for SDS-PAGE — Streamlining Electrophoresis and Blotting Workflows

Bioradiations Staff — Fri, 13 Jul 2012 18:21:28 +0000

Mini-PROTEAN® TGX Stain-Free™ precast gels are now available in gradient format. This unique gel formation allows for fast gel electrophoresis and blotting, and does not require staining and destaining for imaging.

The post New Gradient Format Mini-PROTEAN^® TGX Stain-Free™ Precast Gels for SDS-PAGE — Streamlining Electrophoresis and Blotting Workflows first appeared on Bio-Radiations.

Experimentally Validated PrimePCR™ Assays and Panels for Real-Time PCR

Bioradiations Staff — Fri, 29 Jun 2012 19:04:35 +0000

PrimePCR™ assays set a new standard for real-time PCR. Bio-Rad® collaborated with the leaders in real-time PCR to design, optimize, and experimentally validate every primer pair.

The post Experimentally Validated PrimePCR™ Assays and Panels for Real-Time PCR first appeared on Bio-Radiations.

Image Lab™ 4.1, the Latest Software Version, Addresses the Challenges of Multiplex Analysis and Protein Normalization

Bioradiations Staff — Wed, 13 Jun 2012 20:19:20 +0000

The updated Image Lab image acquisition and analysis software provides improved tools for total protein normalization using the stain-free technology.

The post Image Lab™ 4.1, the Latest Software Version, Addresses the Challenges of Multiplex Analysis and Protein Normalization first appeared on Bio-Radiations.

Bio-Rad’s New 4x Laemmli Sample Buffer for SDS-PAGE

Bioradiations Staff — Tue, 12 Jun 2012 16:57:31 +0000

Detecting dilute protein samples using standard protein gel stains can be problematic. One method of enabling increased sample capacity on gels is to increase the well size. The newly introduced 4x Laemmli sample buffer improves sample loading capacity, improving the detection of low-abundance proteins.

The post Bio-Rad’s New 4x Laemmli Sample Buffer for SDS-PAGE first appeared on Bio-Radiations.

Novel V3 Western Workflow™ Revolutionizes Protein Research

Bioradiations Staff — Thu, 10 May 2012 19:00:24 +0000

Although the Western blot is a core lab procedure, surprisingly little has changed in traditional bench work practice since its inception in 1979. The V3 Western Workflow delivers a streamlined solution to the conventional western blotting workflow as explored here by one protein researcher specializing in chronic obstructive pulmonary disease (COPD).

The post Novel V3 Western Workflow™ Revolutionizes Protein Research first appeared on Bio-Radiations.

Focus on the Biology: Bio-Rad’s New Bio-Plex Data Pro™ Software Simplifies Multiplex Data Analysis

Bioradiations Staff — Fri, 27 Apr 2012 17:28:57 +0000

Many instruments offer multiplexing capability for biomarker measurements. But to handle and make sense of the huge amount of multiplex data requires sophisticated software like Bio-Plex Data Pro, which simplifies organization, import, sorting and visualization of data, and performing calculations and statistical analyses.

The post Focus on the Biology: Bio-Rad’s New Bio-Plex Data Pro™ Software Simplifies Multiplex Data Analysis first appeared on Bio-Radiations.

A Simple Method for Obtaining Absolute Quantification of DNA Molecules Using the Innovative Droplet Digital™ PCR Technology

Bioradiations Staff — Thu, 29 Mar 2012 19:18:12 +0000

Droplet digital PCR is considered the third generation of PCR technology. This technology enables the quantification of absolute measure of target DNA molecules, rather than the relative measure obtained from real-time PCR. Absolute quantification is advantageous in several applications, such as measuring copy number variation, detecting rare sequences and mutations, and analyzing gene expression.

The post A Simple Method for Obtaining Absolute Quantification of DNA Molecules Using the Innovative Droplet Digital™ PCR Technology first appeared on Bio-Radiations.

New Multiplex Assays for Th17 Cytokine Research

Bioradiations Staff — Tue, 06 Mar 2012 20:21:16 +0000

The Bio-Plex Pro human Th17 cytokine panel is a unique blend of magnetic bead-based multiplex immunoassays for the robust and reproducible measurement of 15+1 soluble proteins involved in the T-helper cell type 17 immune response pathway.

The post New Multiplex Assays for Th17 Cytokine Research first appeared on Bio-Radiations.

A New Paradigm for Precise Quantitation of RNA

Bioradiations Staff — Mon, 27 Feb 2012 20:31:17 +0000

The one-step RT-ddPCR kit for probes creates a new paradigm for the precise quantitation of RNA by combining reverse transcription with Droplet Digital™ PCR (ddPCR™), providing an absolute measure of target RNA molecules with unrivaled precision and sensitivity

The post A New Paradigm for Precise Quantitation of RNA first appeared on Bio-Radiations.

Introducing iTaq Universal Supermixes for Highest Quality qPCR Results on Any Instrument

Bioradiations Staff — Fri, 24 Feb 2012 18:21:47 +0000

The iTaq™ universal SYBR® Green supermix and iTaq™ universal probes supermix are ready-to-use 2x supermixes formulated for sensitive, efficient, and reproducible qPCR data on any instrument.

The post Introducing iTaq Universal Supermixes for Highest Quality qPCR Results on Any Instrument first appeared on Bio-Radiations.

QX100™ Droplet Digital™ PCR system

Bioradiations Staff — Wed, 23 Nov 2011 20:42:43 +0000

Bio-Rad’s QX100™ Droplet Digital™ PCR system provides an absolute measure of target DNA molecules with unrivaled precision and accuracy.

The post QX100™ Droplet Digital™ PCR system first appeared on Bio-Radiations.

Bio-Rad Introduces New Bio-Plex® Human Cancer Assays

Bioradiations Staff — Mon, 21 Nov 2011 21:13:37 +0000

Bio-Plex Pro™ Human Cancer Biomarker Panel 1 is a unique blend of magnetic bead-based assays designed to meet the needs of the most discerning preclinical and clinical researchers.

The post Bio-Rad Introduces New Bio-Plex^® Human Cancer Assays first appeared on Bio-Radiations.

Using the new PROTEAN® i12™ IEF System to Achieve Highly Reproducible Data and Extended Separation Over Multiple pH Ranges in a Single Run

Bioradiations Staff — Mon, 21 Nov 2011 20:29:35 +0000

2-D electrophoresis is a multistep technique that separates proteins first by a protein’s isoelectric point and then by its molecular weight. This powerful technique can separate thousands of proteins in a complex proteome and is useful for applications such as protein profiling and biomarker discovery. The drawback of the technique is that it requires multiple steps, each of which can be time-consuming and can contribute to problems with reproducibility.

The post Using the new PROTEAN^® i12™ IEF System to Achieve Highly Reproducible Data and Extended Separation Over Multiple pH Ranges in a Single Run first appeared on Bio-Radiations.

TGX Stain-Free™ Precast Gels

Bioradiations Staff — Wed, 16 Nov 2011 16:52:26 +0000

Mini-PROTEAN® TGX Stain-Free™ and Criterion™ TGX Stain-Free™ precast gels, when combined with Bio-Rad's ChemiDoc™ MP or Gel Doc™ EZ imagers, provide researchers with the fastest protein separation and visualization available using the standard Laemmli system.

The post TGX Stain-Free™ Precast Gels first appeared on Bio-Radiations.

ProteOn™ HTE Sensor Chip

Bioradiations Staff — Mon, 14 Nov 2011 17:54:12 +0000

The HTE sensor chip is designed for label-free biomolecular interaction analysis with polyhistidine-tagged proteins. It features a novel tris-NTA (3-NTA) surface for excellent performance of polyhistidine-tagged protein capture, providing high binding stability and regeneracy. It is an ideal choice for the applications of protein-small molecule and other protein interactions requiring high sensitivity.

The post ProteOn™ HTE Sensor Chip first appeared on Bio-Radiations.

ChemiDoc™ MP Imaging System

Bioradiations Staff — Wed, 05 Oct 2011 21:23:44 +0000

The ChemiDoc MP imaging system enables stain-free operation and lets you visualize proteins at every stage of your experiment. Its flexibility and sensitivity are complemented by a simple, intuitive operation that integrates seamlessly into your workflow.

The post ChemiDoc™ MP Imaging System first appeared on Bio-Radiations.

PROTEAN® i12™ IEF System

Bioradiations Staff — Tue, 04 Oct 2011 17:09:51 +0000

Introducing Bio-Rad's PROTEAN i12 IEF system. Each channel in the i12™ focusing tray is powered by its own power supply, enabling precise control over each IPG strip. This makes it possible to run different sample types, different gradients, and multiple protocols all at the same time.

The post PROTEAN^® i12™ IEF System first appeared on Bio-Radiations.

Immun-Blot® LF (Low Fluorescence) PVDF Membranes

Bioradiations Staff — Mon, 03 Oct 2011 17:27:05 +0000

Immun-Blot LF (low fluorescence) PVDF membranes are protein blotting membranes optimized for fluorescent and multiplex fluorescent applications. They offer high signal-to-background ratio, low autofluorescence, and superior protein retention to maximize blot detection sensitivity and enable downstream quantitation.

The post Immun-Blot^® LF (Low Fluorescence) PVDF Membranes first appeared on Bio-Radiations.

C-96 Autosampler for Reliable Protein Purification Sample Application

Bioradiations Staff — Wed, 15 Jun 2011 19:00:34 +0000

The C-96 autosampler improves the efficiency of protein purification workflows by enabling automated sample application. The straightforward tray designs are easy to use; the standard tray accommodates 84 sample vials (5 ml each) plus three additional vials (10 ml each) for mixing and dilution protocols.

The post C-96 Autosampler for Reliable Protein Purification Sample Application first appeared on Bio-Radiations.

Hard-Shell® 384-Well 480 PCR Plates

Bioradiations Staff — Tue, 14 Jun 2011 19:00:35 +0000

The proprietary warp-free Hard-Shell plates have a reputation as premium plates and were widely used on Bio-Rad, MJ, and Applied Biosystems instruments for the Human Genome Project. Now, researchers can use the same high-quality Hard-Shell plates on Roche LightCycler 480 instruments.

The post Hard-Shell^® 384-Well 480 PCR Plates first appeared on Bio-Radiations.

Using Precision Plus Protein™ WesternC™ Standards to Validate Major Steps in the Western Blotting Workflow

Bioradiations Staff — Mon, 13 Jun 2011 19:00:59 +0000

Western blotting, although a commonly used technique, involves a time-consuming multi step process. The whole western blotting workflow could take up to three days to complete. Thus, having a tool to monitor each of the major steps in the western blotting workflow reduces chances of finding out at the very end of the workflow that an experiment was not successful.

The post Using Precision Plus Protein™ WesternC™ Standards to Validate Major Steps in the Western Blotting Workflow first appeared on Bio-Radiations.

Nuvia™ S Media — A High-Capacity Cation Exchanger for Biomolecule Purification and Downstream Processing

Bioradiations Staff — Thu, 09 Jun 2011 19:00:58 +0000

Nuvia S media is a high-capacity strong cation exchanger (CEX) developed to operate over a range of experimental conditions, allowing scientists to scale up from laboratory- to process-scale more quickly and easily. Our data demonstrate that the high capacity and superb purification of Nuvia S media can significantly improve productivity by offering the robustness, capacity, and speed for processing large load volumes with smaller columns and less buffer consumption.

The post Nuvia™ S Media — A High-Capacity Cation Exchanger for Biomolecule Purification and Downstream Processing first appeared on Bio-Radiations.

Bio-Plex Pro™ Mouse Th17 Cytokines

Bioradiations Staff — Thu, 09 Jun 2011 19:00:02 +0000

Bio-Plex Pro™ mouse Th17 assays are magnetic bead–based multiplex assays that offer accurate and reproducible measurements of 20 target molecules in serum, plasma, and tissue culture sample types for mouse models. These assays have been developed to provide reliable performance with the flexibility required to meet all of your research needs.

The post Bio-Plex Pro™ Mouse Th17 Cytokines first appeared on Bio-Radiations.