ArticlesDroplet Digital PCR (ddPCR)

Maximizing the Impact of Wastewater-Based Epidemiology with ddPCR Technology

As SARS-CoV-2 becomes an endemic agent worldwide, communities and health agencies must figure out how to identify novel variants and track infection rates in ways that are sustainable, sensitive, and accurate. Fortunately, wastewater-based epidemiology (WBE) has proven its ability to play an important role in monitoring COVID-19 outbreaks, and Droplet Digital PCR (ddPCR) has become a cornerstone method for ongoing wastewater-based disease surveillance. In this article, we review the role of wastewater-based testing in community health before, during, and beyond the COVID-19 pandemic, and we explore why ddPCR technology is ideally suited for this application as it continues to expand and evolve.
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ArticlesDroplet Digital PCR (ddPCR)

Using ddPCR Technology to Improve Cancer Detection and Treatment Efficacy Monitoring

Cancer remains a leading cause of death worldwide. However, as cancer treatments continue to improve and diagnoses happen sooner, more and more patients are experiencing remission. To further increase survival rates and reduce unnecessary treatment, scientists and clinicians are turning to ultra-sensitive molecular analysis to inform treatment decisions and predict and detect relapse.
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ArticlesDroplet Digital PCR (ddPCR)Drug Discovery and Development

Precise Cell and Gene Therapy Potency Quantification

Inadequate quality control assays shouldn’t limit cell and gene therapy applications. Instead, quantifying the potency of cell and gene therapies is essential for successful therapeutics. In this article, we describe multiple leading potency assays developed using Droplet Digital PCR (ddPCR) technology, including an assay that quantifies transgene integration and expression in one step.
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ArticlesDroplet Digital PCR (ddPCR)

Modernizing Gene Editing Detection with Droplet Digital PCR

Gene editing is only useful if it’s successful. Read how scientists are leveraging the unparalleled accuracy and specificity of ddPCR technology to optimize quality control in gene editing projects, including HIV detection and CAR-T cell generation.
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ArticlesDroplet Digital PCR (ddPCR)General Interest

Rapid, Sensitive Cancer Biomarker Screening in cfDNA

Disease-associated mutations can be prognostic of outcome and inform treatment choices. However, traditional tissue biopsies limit the ability to implement personalized treatments. Read about how multiplex digital PCR can enable the tracking of treatment efficacy using liquid biopsies.
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ArticlesDroplet Digital PCR (ddPCR)Featured StoriesProtocols and Tips

Digital PCR: Helpful Tips When Using Droplet Partitioning Technology

Digital PCR offers a highly sensitive alternative to conventional qPCR, enabling absolute quantification of nucleic acids and rare allele detection. The tips in this article help you set up and optimize your digital PCR experiments when using droplet partitioning technology.
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Droplet Digital PCR (ddPCR)Droplet Digital PCR (ddPCR) VideoVideos

Research Review: Phasing Genomes using
Droplet Digital™ PCR

Find out how a new Droplet Digital PCR-based technique called Drop Phase lets you quickly and easily phase genomes to better understand diseases like cystic fibrosis.
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Past WebinarsWebinars

Introduction to Droplet Digital™ PCR: Workflow and Applications

This webinar introduces the concept, workflow, and performance of Droplet Digital PCR and highlights the diverse applications showcased in recent journal publications.  
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Past WebinarsWebinars

Applying Droplet Digital™ PCR to the Study of Environmental Samples

This webinar covers the use of ddPCR with environmental samples. The QX200™ Droplet Digital PCR (ddPCR™) System, Bio-Rad’s second-generation digital PCR…  
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Past WebinarsWebinars

Droplet Digital™ PCR Tips & Tricks: ddPCR™ Assay Design

The webinar discusses tips and tricks used in Droplet Digital PCR (ddPCR™) assay design. Topics covered include the availability of commercial PrimePCR™ ddPCR Assays…  
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