ArticlesDrug Discovery and DevelopmentFeatured StoriesGeneral Interest

Understanding Biomarkers for Better Drug Discovery and Development

Biomarker intelligence comes from understanding the biomarker landscape, that is, the characteristics and features of biomarkers, and disease pathways. This understanding, in turn, helps to recognize the utility of biomarkers. In this study, we partnered with Amplion Inc., to investigate biomarker usage in 24 immunotherapy companies. We found the most popular biomarkers and learnt how they are being used by each company.
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ArticlesDrug Discovery and DevelopmentFeatured StoriesGeneral Interest

Biosimilars. Are They Ready for Primetime?

Is the hype surrounding biosimilars real or simply a hopeful view on an exceedingly expensive drug market? Read this article to find out more about biosimilars and understand the challenges facing the biosimilars industry.
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ArticlesCell BiologyGeneral Interest

Understanding the Eukaryotic Cell Cycle

The eukaryotic cell cycle is an evolutionarily conserved process that results in the replication of cells. Read this mini review to better understand the eukaryotic cell cycle and get an overview of common molecular techniques used to evaluate proliferating cells.
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ArticlesChromatographyFeatured StoriesGeneral Interest

Modern Improvements to Classic Technologies: Innovating Electrophoresis and Chromatography Upstream of Protein Characterization to Speed Up Research

When testing new drug therapies, it is essential to know the identity of the protein being tested. Chromatography is a commonly used technique to separate complex biological mixtures and isolate proteins of interest prior to downstream characterization. Learn more about how automating chromatography and stain-free technology are helping to save time and effort in protein purification.
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ArticlesElectrophoresis/Western BlottingGeneral Interest

Identify Major Immune Cell Types by Their CD Marker Expression

Our new immune cell lineage and marker database provides an interactive way to help you easily examine detailed marker data, view immune cell marker expression, and find the antibody to your marker. Learn more and try out the interactive tool for yourself.
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ArticlesDrug Discovery and DevelopmentFeatured StoriesGeneral Interest

What Pharma Is Doing to Triple Clinical Trial Successes

The typical success rate of a clinical trial is less than ten percent. Pharmaceutical companies are using a variety of methods to save time and reduce costs to get drugs to market faster. Biomarker screening is proving to be an effective way to improve the drug discovery and development process. See one of the ways Pharma companies can identify the most relevant biomarkers.
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ArticlesElectrophoresis/Western BlottingGeneral Interest

Validating Antibodies — the Good, the Bad, and the Necessary

Despite the fact that antibodies are one of the most frequently used tools in life science and clinical research, there are no universally accepted guidelines to ensure that they have been properly validated. Learn about the issues facing researchers and what antibody suppliers and researchers can do to ensure that the research being carried out is trustworthy and is helping to improve overall data quality.
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ArticlesDroplet Digital PCR (ddPCR)General Interest

Rapid, Sensitive Cancer Biomarker Screening in cfDNA

Disease-associated mutations can be prognostic of outcome and inform treatment choices. However, traditional tissue biopsies limit the ability to implement personalized treatments. Read about how multiplex digital PCR can enable the tracking of treatment efficacy using liquid biopsies.
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ArticlesDrug Discovery and DevelopmentFeatured StoriesGeneral Interest

Erasing Disease: How Gene Editing is Changing Genetic Therapies

Gene augmentation and antisense therapies treat disease by providing a functional copy of faulty gene or repressing its expression. Find out how gene editing tools, like CRISPR, promise a more permanent cure.
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ArticlesCell BiologyGeneral Interest

Assessing Cell Health: Necroptosis

In this fourth and final part of the series on assessing the health of your cells, we review the different stages of necroptosis, see how it differs from apoptosis, and learn about the various methods of assessing cellular necroptosis.
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